Showing papers by "British Hospital published in 1999"
TL;DR: The findings strongly support the negative effect of AEDs upon colour vision discrimination, most likely due to changes at the retinal processing level.
Abstract: Diplopia, blurred vision and colour disturbances are well-known side effects associated with anti-epileptic drugs (AEDs). Farnsworth-Munsell 100-hue colour test (F-100) is an accepted and sensitive to
33 citations
TL;DR: VATS débridement for loculated fibrinopurulent postpneumonic empyema offers better results than thoracotomy in terms of resolution of the disease and length of stay in hospital and seems to be more advantageous, resulting in fewer surgical sequelae, lower cost, less labor impediment, and better cosmesis.
Abstract: Postpneumonic empyema complicates 5% of all pneumonia cases. The loculated fibrinopurulent stage cannot be resolved by drainage tube insertion alone; it requires a debriding limited thoracotomy. Recent reports of series seem to indicate that video-assisted thoracic surgery (VATS) can replace thoracotomy advantageously. Eighty-six cases of postpneumonic empyema were operated on in our institution during the last 12 years: 33 cases (group I) using limited thoracotomy (1985–1991) and 53 by VATS (1992–1996). Data were collected prospectively for group II and retrospectively for the first group. The two populations were comparable in age, gender, stage of disease, and co-morbid status. There were no significant differences between the groups. VATS debridement for loculated fibrinopurulent postpneumonic empyema offers better results than thoracotomy in terms of resolution of the disease and length of stay in hospital. It also seems to be more advantageous, resulting in fewer surgical sequelae, lower cost, less labor impediment, and better cosmesis.
15 citations
TL;DR: The incidence of pain in the post anasthesia care unit (PACU) and postoperative pain was very low and not related to the administration of fentanyl, or whether the surgical procedure performed was a meniscectomy or chondroplasty.
4 citations
Journal Article•
TL;DR: The pharmacological therapy of HF is proving to be more an art than a science, as numerous agents have to be tuned against each other to produce an overall effect that is beneficial.
Abstract: The incidence of heart failure (HF) is increasing while numerous pharmacological breakthroughs have been accomplished in the last two decades. Mortality remains high and is comparable to mortality due to oncologic disease. Coronary artery disease and hypertension are the primary causes of heart failure in Western societies while valvular heart disease is a significant cause in economically underdeveloped societies. While there are many pharmacological therapies for systolic disfunction, little is known about the optimal way to treat diastolic dysfunction. Although William Withering described the properties of digitalis in 1785, two hundred years passed before a scientific trial documented its benefit in HF. Skilled dissection and probing of the molecular basis of cardiac muscle contraction led to the development of numerous compounds postulated to be more effective than digitalis, only to disappoint repeatedly in numerous trials. In contrast, ACE inhibitors (ACEI) revolutionized the management of HF and it is unlikely that another class of agents will show dramatic improvements like the ACEI. Therefore, the pharmacological therapy of HF is proving to be more an art than a science, as numerous agents have to be tuned against each other to produce an overall effect that is beneficial.
2 citations