Institution
British Thoracic Society
Nonprofit•London, United Kingdom•
About: British Thoracic Society is a nonprofit organization based out in London, United Kingdom. It is known for research contribution in the topics: Guideline & Population. The organization has 84 authors who have published 62 publications receiving 3604 citations.
Topics: Guideline, Population, Community-acquired pneumonia, Pneumonia, Audit
Papers published on a yearly basis
Papers
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Aberdeen Royal Infirmary1, Freeman Hospital2, Queen Mary University of London3, University of Strathclyde4, St George's, University of London5, Southampton General Hospital6, Boston Children's Hospital7, Imperial College London8, British Thoracic Society9, Queen's University10, St Thomas' Hospital11, Royal Hospital for Sick Children12
TL;DR: These guidelines have been replaced by British Guideline on the Management of Asthma.
Abstract: These guidelines have been replaced by British Guideline on the Management of Asthma. A national clinical guideline. Superseded By 2012 Revision Of 2008 Guideline: British Guideline on the Management of Asthma. Thorax 2008 May; 63(Suppl 4): 1–121.
1,475 citations
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Papworth Hospital1, Abertawe Bro Morgannwg University Health Board2, St James's University Hospital3, Newcastle University4, Manchester Royal Infirmary5, Western General Hospital6, National Institutes of Health7, Guy's and St Thomas' NHS Foundation Trust8, British Thoracic Society9, University of Manchester10, Great Ormond Street Hospital for Children NHS Foundation Trust11, Southmead Hospital12, Queen Alexandra Hospital13, University of Cambridge14
TL;DR: Recommendations and recommendations on what samples should be used to detect pulmonary non-tuberculous mycobacterial infection and how to define lung disease attributable to NTM infection are presented.
Abstract: Section 4: What is the evidence for transmission of NTM between individuals?
Recommendation
Section 5: How should the lung disease attributable to NTM infection be defined?
Recommendation
Good practice point
Section 6: What samples should be used to detect pulmonary non-tuberculous mycobacterial infection?
Recommendations
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Section …
446 citations
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TL;DR: After excluding those individuals who required steroids for control of symptoms, approximately half of the remaining patients with sarcoidosis and pulmonary shadowing showed spontaneous radiographic improvement during six months of observation.
Abstract: BACKGROUND: Corticosteroids suppress disease activity in pulmonary sarcoidosis and their use produces symptomatic, radiographic, and functional improvement. There is, however, uncertainty regarding their effects on the overall natural history of the condition and long term benefit is unproven. METHODS: Patients with pulmonary radiographic shadowing due to sarcoidosis were recruited in a multicentre study. Those who, in the first six months after entry to the study, neither required prednisolone for symptoms nor showed radiographic improvement were allocated at six months to receive either long term steroid treatment (group L) or selective treatment (group S), with regular assessment over the subsequent five years. Patients in group L were scheduled to receive steroid treatment for at least 18 months with the policy of achieving and maintaining maximal radiographic clearing, while in group S treatment was reserved for use only if warranted by later development of symptoms or deteriorating lung function. Symptoms, radiographic appearances, and respiratory function were assessed periodically during the study. RESULTS: One hundred and forty nine patients were followed: 33 required prednisolone for troublesome symptoms within six months of entry and 58 showed radiographic improvement over this period. The remaining 58 patients were allocated to groups L (n = 27) and S (n = 31). Patients in group L showed greater improvements in symptoms, respiratory function, and radiographic appearances than those in group S, although the differences were not large. After adjusting for differences at the time of allocation, the average difference in vital capacity between groups L and S at final assessment was 9% of the predicted value. Side effects of treatment were frequent but usually mild, necessitating withdrawal in only two individuals. CONCLUSIONS: After excluding those individuals who required steroids for control of symptoms, approximately half of the remaining patients with sarcoidosis and pulmonary shadowing showed spontaneous radiographic improvement during six months of observation. In those in whom the radiograph failed to improve, prolonged steroid treatment with the aim of optimising radiographic appearances resulted in a significantly better long term functional outcome.
269 citations
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TL;DR: Overall 21 patients died (12 with empyema as the major cause); two had been surgically treated and six months after discharge, all but six survivors had regained their previous health.
Abstract: We report a prospective multi-centre study of the clinical course and hospital management of thoracic empyema in 119 patients (mean age 54.8). The commonest presenting symptom was malaise (75%), 55% were febrile; 31% were previously well with no predisposing condition. Initial treatments were antibiotics alone (5), needle aspirations (46), intercostal tube drainage (61), rib resection (3) and decortication (4). Overall, intercostal drainage was used in 77 patients (16 failed aspirations), surgical rib resection in 24 (1 failed aspirations, 20 failed drainage), and surgical decortication in 28 (6 failed aspirations, 17 failed drainage). Only 4 patients received intrapleural fibrinolytic agents. Aspiration and drainage were likely to fail if the empyema was > 40% of the hemithorax. Median time from treatment start to discharge was: aspirations, 26 days; drainage, 23 days; resection 11 days; decortication, 12 days. Overall 21 patients died (12 with empyema as the major cause); two had been surgically treated. Mortality correlated with age, diabetes, heart failure, and low serum albumin at admission. Infecting organisms, identified in 109 patients (92%) included anaerobes (37), Str. melleri (36), and Str. pneumoniae (28). Six months after discharge, all but six survivors had regained their previous health.
254 citations
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British Thoracic Society1, St James's University Hospital2, Barts Health NHS Trust3, Coventry Health Care4, Royal Surrey County Hospital5, North Bristol NHS Trust6, University of Bristol7, University Hospital of South Manchester NHS Foundation Trust8, Central Manchester University Hospitals NHS Foundation Trust9, University of Plymouth10, Guy's and St Thomas' NHS Foundation Trust11, Imperial College London12, Queen's University13, Royal College of Physicians14
TL;DR: Oxygen enrichment should be adjusted to achieve SaO2 88–92% in all causes of acute hypercapnic respiratory failure (AHRF) treated by NIV, and oxygen should be entrained as close to the patient as possible.
Abstract: ### Principles of mechanical ventilation
#### Modes of mechanical ventilation
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1. Pressure-targeted ventilators are the devices of choice for acute NIV (Grade B).
Good practice points
#### Choice of interface for NIV
Recommendation
2. A full face mask (FFM) should usually be the first type of interface used (Grade D).
Good practice points
#### Indications for and contra-indications to NIV in AHRF
Recommendation
3. The presence of adverse features increase the risk of NIV failure and should prompt consideration of placement in high dependency unit (HDU)/intensive care unit (ICU) (Grade C).
Good practice points
#### Monitoring during NIV
Good practice points
#### Supplemental oxygen therapy with NIV
Recommendations
4. Oxygen enrichment should be adjusted to achieve SaO2 88–92% in all causes of acute hypercapnic respiratory failure (AHRF) treated by NIV (Grade A).
5. Oxygen should be entrained as close to the patient as possible (Grade C).
Good practice points
244 citations
Authors
Showing all 84 results
Name | H-index | Papers | Citations |
---|---|---|---|
Alvar Agusti | 110 | 590 | 69397 |
Andrew Bush | 99 | 935 | 40450 |
Toby M. Maher | 61 | 404 | 13382 |
Sally J Singh | 53 | 233 | 16824 |
Nicholas S Hopkinson | 52 | 346 | 11765 |
John R. Hurst | 51 | 281 | 12644 |
Charlotte E. Bolton | 30 | 134 | 3790 |
Sarah Dennis | 26 | 118 | 2545 |
Jonathan Bennett | 22 | 47 | 2617 |
Paul Walker | 16 | 58 | 1770 |
Brian D W Harrison | 14 | 22 | 839 |
Sally Welham | 13 | 21 | 389 |
R K Coker | 13 | 29 | 1581 |
Michael A Gibbons | 11 | 34 | 1104 |
Sian Williams | 11 | 39 | 535 |