Institution
Brno University of Technology
Education•Brno, Czechia•
About: Brno University of Technology is a education organization based out in Brno, Czechia. It is known for research contribution in the topics: Fracture mechanics & Filter (video). The organization has 6339 authors who have published 15226 publications receiving 194088 citations. The organization is also known as: Vysoké učení technické v Brně & BUT.
Papers published on a yearly basis
Papers
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TL;DR: Antioxidant capacity and antimutagenicity of green tea extracts was higher than activity of tea catechins and flavonoids and total radical-trapping antioxidant parameter (TRAP) method.
Abstract: In this work biological effects of two common kinds of green tea (Chinese Gunpowder and Japanese Sencha) were analyzed using three independent tests of antimutagenicity: 1) the Ames test with Salmonella typhimurium TA98, 2) cytogenetic analysis of peripheral blood lymphocytes (CAPL), and 3) test with Saccharomyces cerevisiae D7. Tea extracts were allowed to be antimutagenic based on their ability to inhibit the mutagenic effect of standard mutagens. Amounts of (-)catechin and (-)catechin gallate in tea extracts were determined by high performance liquid chromatography on reversed phase (RP-HPLC). Antioxidant capacity was found using total radical-trapping antioxidant parameter (TRAP) method. Extracts from Gunpowder and Sencha exhibited high antimutagenic activity in the Ames test (24.7+/-3.7% and 34.1+/-2, 1% of inhibition without metabolic activation; 74.9+/-1.7% and 62.7+/-4.3% of inhibition with metabolic activation, respectively) as well as in S. cerevisiae D7 test (Gunpowder: 62.7+/-5.7% of Trp convertants inhibition and 52.6+/-5.3% of Ilv revertants inhibition; Sencha: 45.6+/-4.2% of Trp convertants inhibition, 50.0+/-4.8% of Ilv revertants inhibition). In the CAPL method reduced number of abberant cells as well as decreased number of chromosome breaks was observed using both green tea extracts. Antioxidant capacity and antimutagenicity of green tea extracts was higher than activity of tea catechins and flavonoids.
54 citations
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TL;DR: Four different derivatives of diphenyl-diketo-pyrrolopyrrole with alkyl side groups were synthesized to increase their solubility and revealed that the substitution influenced molecular geometry and subsequently modified absorption and photoluminescence spectra.
Abstract: Four different derivatives of diphenyl-diketo-pyrrolopyrrole (DPP) with alkyl side groups were synthesized to increase their solubility Quantum chemical calculations revealed that the substitution influenced molecular geometry and subsequently modified absorption and photoluminescence spectra The theoretical results were confirmed by experimental characterization With increasing phenyl torsion the vibrational structure was less pronounced and larger Stokes shift was observed Simultaneously, the molar absorption coefficient decreased as the deformation increased On the other hand, the measured fluorescence quantum yields were modified only slightly This indicates the possibility to prepare soluble derivatives without loss of quantum yields and to use these materials for construction of efficient and stable electroluminescent devices Furthermore, the electroluminescence of the thin layer devices based on the soluble low molecular DPPs were characterized and discussed
54 citations
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TL;DR: Evaluated genomes of all coronaviruses sequenced to date found much evidence of putative G-quadruplex sites and even much more of inverted repeats (IRs) loci, which indicate a possible mechanism for genomic RNA packaging.
Abstract: Non-canonical nucleic acid structures play important roles in the regulation of molecular processes. Considering the importance of the ongoing coronavirus crisis, we decided to evaluate genomes of all coronaviruses sequenced to date (stated more broadly, the order Nidovirales) to determine if they contain non-canonical nucleic acid structures. We discovered much evidence of putative G-quadruplex sites and even much more of inverted repeats (IRs) loci, which in fact are ubiquitous along the whole genomic sequence and indicate a possible mechanism for genomic RNA packaging. The most notable enrichment of IRs was found inside 5'UTR for IRs of size 12+ nucleotides, and the most notable enrichment of putative quadruplex sites (PQSs) was located before 3'UTR, inside 5'UTR, and before mRNA. This indicates crucial regulatory roles for both IRs and PQSs. Moreover, we found multiple G-quadruplex binding motifs in human proteins having potential for binding of SARS-CoV-2 RNA. Non-canonical nucleic acids structures in Nidovirales and in novel SARS-CoV-2 are therefore promising druggable structures that can be targeted and utilized in the future.
54 citations
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TL;DR: In this article, the authors provided high resolution mapping of uranium in sandstone-hosted uranium ores using laser-induced breakdown spectroscopy (LIBS) technique.
53 citations
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TL;DR: The possibility of using the smartphone as a fast alternative to conventional and specialized devices for SpO2, HR, and BP estimation was statistically proven and the smartphone quantum efficiency did not have to be known.
53 citations
Authors
Showing all 6383 results
Name | H-index | Papers | Citations |
---|---|---|---|
Georg Kresse | 111 | 430 | 244729 |
Patrik Schmuki | 109 | 763 | 52669 |
Michael Schmid | 88 | 715 | 30874 |
Robert M. Malina | 88 | 691 | 38277 |
Jiří Jaromír Klemeš | 64 | 565 | 14892 |
Alessandro Piccolo | 62 | 284 | 14332 |
René Kizek | 61 | 672 | 16554 |
George Danezis | 59 | 209 | 11516 |
Stevo Stević | 58 | 374 | 9832 |
Edvin Lundgren | 57 | 286 | 10158 |
Franz Halberg | 55 | 750 | 15400 |
Vojtech Adam | 55 | 611 | 14442 |
Lukas Burget | 53 | 252 | 21375 |
Jan Cermak | 53 | 238 | 9563 |
Hynek Hermansky | 51 | 317 | 14372 |