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Institution

Brown University

EducationProvidence, Rhode Island, United States
About: Brown University is a education organization based out in Providence, Rhode Island, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35778 authors who have published 90896 publications receiving 4471489 citations. The organization is also known as: brown.edu & Brown.


Papers
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Journal ArticleDOI
01 Nov 1998-Chest
TL;DR: The key recommendations in this chapter are the following: for patients with acute ischemic stroke, administration of IV tissue plasminogen activator (tPA) if treatment is initiated within 3 h of clearly defined symptom onset (Grade 1A).

630 citations

Posted Content
TL;DR: There is substantial room for improvement in NLI systems, and the HANS dataset can motivate and measure progress in this area, which contains many examples where the heuristics fail.
Abstract: A machine learning system can score well on a given test set by relying on heuristics that are effective for frequent example types but break down in more challenging cases. We study this issue within natural language inference (NLI), the task of determining whether one sentence entails another. We hypothesize that statistical NLI models may adopt three fallible syntactic heuristics: the lexical overlap heuristic, the subsequence heuristic, and the constituent heuristic. To determine whether models have adopted these heuristics, we introduce a controlled evaluation set called HANS (Heuristic Analysis for NLI Systems), which contains many examples where the heuristics fail. We find that models trained on MNLI, including BERT, a state-of-the-art model, perform very poorly on HANS, suggesting that they have indeed adopted these heuristics. We conclude that there is substantial room for improvement in NLI systems, and that the HANS dataset can motivate and measure progress in this area

630 citations

Journal ArticleDOI
TL;DR: An updated list of 30 essential items that should be included in every report of a diagnostic accuracy study is presented, which incorporates recent evidence about sources of bias and variability in diagnostic accuracy and is intended to facilitate the use of STARD.
Abstract: Incomplete reporting has been identified as a major source of avoidable waste in biomedical research. Essential information is often not provided in study reports, impeding the identification, critical appraisal, and replication of studies. To improve the quality of reporting of diagnostic accuracy studies, the Standards for Reporting of Diagnostic Accuracy Studies (STARD) statement was developed. Here we present STARD 2015, an updated list of 30 essential items that should be included in every report of a diagnostic accuracy study. This update incorporates recent evidence about sources of bias and variability in diagnostic accuracy and is intended to facilitate the use of STARD. As such, STARD 2015 may help to improve completeness and transparency in reporting of diagnostic accuracy studies.

630 citations

Patent
25 Jun 1992
TL;DR: Refillable immunoisolatory neurological therapy devices for local and controlled delivery of a biologically active factor to the brain of a patient are described in this paper, where the authors include a cell chamber adapted for infusion with nsecretory cells and having at least one semipermeable or permselective surface across which biologically active factors secreted by the cells can be delivered.
Abstract: Refillable immunoisolatory neurological therapy devices for local and controlled delivery of a biologically active factor to the brain of a patient. The devices include a cell chamber adapted for infusion with nsecretory cells and having at least one semipermeable or permselective surface across which biologically active factors secreted by the cells can be delivered to the brain. The devices also include means for introducing secretory cells into the cell chamber, and means for renewing the cells or cell medium.

630 citations

Journal ArticleDOI
TL;DR: In this article, an analysis of accuracy and stability of algorithms for the integration of elastoplastic constitutive relations is carried out in the presence of the plastic consistency condition, and the criteria derived are used to identify two second-order accurate members of the proposed algorithms.
Abstract: An analysis of accuracy and stability of algorithms for the integration of elastoplastic constitutive relations is carried out in this paper. Reference is made to a very general internal variable formulation of plasticity and to two families of algorithms that generalize the well-known trapezoidal and midpoint rules to fit the present context. Other integration schemes such as the radial return, mean normal and closest point procedures are particular cases of this general formulation. The meaning of first and second-order accuracy in the presence of the plastic consistency condition is examined in detail, and the criteria derived are used to identify two second-order accurate members of the proposed algorithms. A general methodology is also derived whereby the numerical stability properties of integration schemes can be systematically assessed. With the aid of this methodology, the generalized midpoint rule is seen to have far better stability properties than the generalized trapezoidal rule. Finally, numerical examples are presented that illustrate the performance of the algorithms.

629 citations


Authors

Showing all 36143 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Robert Langer2812324326306
Robert M. Califf1961561167961
Eric J. Topol1931373151025
Joan Massagué189408149951
Joseph Biederman1791012117440
Gonçalo R. Abecasis179595230323
James F. Sallis169825144836
Steven N. Blair165879132929
Charles M. Lieber165521132811
J. S. Lange1602083145919
Christopher J. O'Donnell159869126278
Charles M. Perou156573202951
David J. Mooney15669594172
Richard J. Davidson15660291414
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023126
2022591
20215,550
20205,321
20194,806
20184,462