Brown University

About: Brown University is a education organization based out in Providence, Rhode Island, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35778 authors who have published 90896 publications receiving 4471489 citations. The organization is also known as: brown.edu & Brown.

The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution

Abstract: An understanding of ctenophore biology is critical for reconstructing events that occurred early in animal evolution. Toward this goal, we have sequenced, assembled, and annotated the genome of the ctenophore Mnemiopsis leidyi. Our phylogenomic analyses of both amino acid positions and gene content suggest that ctenophores rather than sponges are the sister lineage to all other animals. Mnemiopsis lacks many of the genes found in bilaterian mesodermal cell types, suggesting that these cell types evolved independently. The set of neural genes in Mnemiopsis is similar to that of sponges, indicating that sponges may have lost a nervous system. These results present a newly supported view of early animal evolution that accounts for major losses and/or gains of sophisticated cell types, including nerve and muscle cells.

Statistics of natural images and models

Abstract: Large calibrated datasets of 'random' natural images have recently become available. These make possible precise and intensive statistical studies of the local nature of images. We report results ranging from the simplest single pixel intensity to joint distribution of 3 Haar wavelet responses. Some of these statistics shed light on old issues such as the near scale-invariance of image statistics and some are entirely new. We fit mathematical models to some of the statistics and explain others in terms of local image features.

Character and Spatial Distribution of OH/H2O on the Surface of the Moon Seen by M3 on Chandrayaan-1

Abstract: The search for water on the surface of the anhydrous Moon had remained an unfulfilled quest for 40 years. However, the Moon Mineralogy Mapper (M 3 ) on Chandrayaan-1 has recently detected absorption features near 2.8 to 3.0 micrometers on the surface of the Moon. For silicate bodies, such features are typically attributed to hydroxyl- and/or water-bearing materials. On the Moon, the feature is seen as a widely distributed absorption that appears strongest at cooler high latitudes and at several fresh feldspathic craters. The general lack of correlation of this feature in sunlit M 3 data with neutron spectrometer hydrogen abundance data suggests that the formation and retention of hydroxyl and water are ongoing surficial processes. Hydroxyl/water production processes may feed polar cold traps and make the lunar regolith a candidate source of volatiles for human exploration.

A unified model of NMDA receptor-dependent bidirectional synaptic plasticity

Abstract: Synapses in the brain are bidirectionally modifiable, but the routes of induction are diverse. In various experimental paradigms, N-methyl-d-aspartate receptor-dependent long-term depression and long-term potentiation have been induced selectively by varying the membrane potential of the postsynaptic neurons during presynaptic stimulation of a constant frequency, the rate of presynaptic stimulation, and the timing of pre- and postsynaptic action potentials. In this paper, we present a mathematical embodiment of bidirectional synaptic plasticity that is able to explain diverse induction protocols with a fixed set of parameters. The key assumptions and consequences of the model can be tested experimentally; further, the model provides the foundation for a unified theory of N-methyl-d-aspartate receptor-dependent synaptic plasticity.

From Malthusian stagnation to modern growth.

Abstract: This paper investigates the historical evolution of the relationship among population growth technological change and standard of living. The analysis focuses on two most important differences among the Malthusian Regime Post-Malthusian Regime and Modern Growth Regime. These were the behavior of income per capita and the relationship between the level of income per capita and the population growth rate. The Modern Growth Regime is characterized by steady growth in both income per capita and the level of technology. In the Malthusian regime technological progress and population growth was glacial by modern standards and income per capita was fairly constant. In contrast to the Modern Growth Regime the relationship between per capita income and population growth in the Malthusian Regime was positive. Post-Malthusian Regime shared one characteristic with each of the two regimes. In addition this paper developed and described an endogenous-growth model consistent with the above mentioned transition process.