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Institution

Brown University

EducationProvidence, Rhode Island, United States
About: Brown University is a education organization based out in Providence, Rhode Island, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35778 authors who have published 90896 publications receiving 4471489 citations. The organization is also known as: brown.edu & Brown.


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01 Jan 1974
TL;DR: In this paper, the authors proposed a method to detect cracks in a crack-penetrization model, based on the Griffith criterion, which is used to detect the presence of a crack at a crack tip.
Abstract: I Principles.- 1 Summary of basic problems and concepts.- 1.1 Introduction.- 1.2 A crack in a structure.- 1.3 The stress at a crack tip.- 1.4 The Griffith criterion.- 1.5 The crack opening displacement criterion.- 1.6 Crack propagation.- 1.7 Closure.- 2 Mechanisms of fracture and crack growth.- 2.1 Introduction.- 2.2 Cleavage fracture.- 2.3 Ductile fracture.- 2.4 Fatigue cracking.- 2.5 Environment assisted cracking.- 2.6 Service failure analysis.- 3 The elastic crack-tip stress field.- 3.1 The Airy stress function.- 3.2 Complex stress functions.- 3.3 Solution to crack problems.- 3.4 The effect of finite size.- 3.5 Special cases.- 3.6 Elliptical cracks.- 3.7 Some useful expressions.- 4 The crack tip plastic zone.- 4.1 The Irwin plastic zone correction.- 4.2 The Dugdale approach.- 4.3 The shape of the plastic zone.- 4.4 Plane stress versus plane strain.- 4.5 Plastic constraint factor.- 4.6 The thickness effect.- 5 The energy principle.- 5.1 The energy release rate.- 5.2 The criterion for crack growth.- 5.3 The crack resistance (R curve).- 5.4 Compliance.- 5.5 The J integral.- 5.6 Tearing modulus.- 5.7 Stability.- 6 Dynamics and crack arrest.- 6.1 Crack speed and kinetic energy.- 6.2 The dynamic stress intensity and elastic energy release rate.- 6.3 Crack branching.- 6.4 The principles of crack arrest.- 6.5 Crack arrest in practice.- 6.6 Dynamic fracture toughness.- 7 Plane strain fracture toughness.- 7.1 The standard test.- 7.2 Size requirements.- 7.3 Non-linearity.- 7.4 Applicability.- 8 Plane stress and transitional behaviour.- 8.1 Introduction.- 8.2 An engineering concept of plane stress.- 8.3 The R curve concept.- 8.4 The thickness effect.- 8.5 Plane stress testing.- 8.6 Closure.- 9 Elastic-plastic fracture.- 9.1 Fracture beyond general yield.- 9.2 The crack tip opening displacement.- 9.3 The possible use of the CTOD criterion.- 9.4 Experimental determination of CTOd.- 9.5 Parameters affecting the critical CTOD.- 9.6 Limitations, fracture at general yield.- 9.7 Use of the J integral.- 9.8 Limitations of the J integral.- 9.9 Measurement of JIc and JR.- 9.10 Closure.- 10 Fatigue crack propagation.- 10.1 Introduction.- 10.2 Crack growth and the stress intensity factor.- 10.3 Factors affecting crack propagation.- 10.4 Variable amplitude service loading.- 10.5 Retardation models.- 10.6 Similitude.- 10.7 Small cracks.- 10.8 Closure.- 11 Fracture resistance of materials.- 11.1 Fracture criteria.- 11.2 Fatigue cracking criteria.- 11.3 The effect of alloying and second phase particles.- 11.4 Effect of processing, anisotropy.- 11.5 Effect of temperature.- 11.6 Closure.- II Applications.- 12 Fail-safety and damage tolerance.- 12.1 Introduction.- 12.2 Means to provide fail-safety.- 12.3 Required information for fracture mechanics approach.- 12.4 Closure.- 13 Determination of stress intensity factors.- 13.1 Introduction.- 13.2 Analytical and numerical methods.- 13.3 Finite element methods.- 13.4 Experimental methods.- 14 Practical problems.- 14.1 Introduction.- 14.2 Through cracks emanating from holes.- 14.3 Corner cracks at holes.- 14.4 Cracks approaching holes.- 14.5 Combined loading.- 14.6 Fatigue crack growth under mixed mode loading.- 14.7 Biaxial loading.- 14.8 Fracture toughness of weldments.- 14.9 Service failure analysis.- 15 Fracture of structures.- 15.1 Introduction.- 15.2 Pressure vessels and pipelines.- 15.3 "Leak-bcfore-break" criterion.- 15.4 Material selection.- 15.5 The use of the J integral for structural analysis.- 15.6 Collapse analysis.- 15.7 Accuracy of fracture calculations.- 16 Stiffened sheet structures.- 16.1 Introduction.- 16.2 Analysis.- 16.3 Fatigue crack propagation.- 16.4 Residual strength.- 16.5 The R curve and the residual strength of stiffened panels.- 16.6 Other analysis methods.- 16.7 Crack arrest.- 16.8 Closure.- 17 Prediction of fatigue crack growth.- 17.1 Introduction.- 17.2 The load spectrum.- 17.3 Approximation of the stress spectrum.- 17.4 Generation of a stress history.- 17.5 Crack growth integration.- 17.6 Accuracy of predictions.- 17.7 Safety factors.- Author index.

2,539 citations

Journal ArticleDOI
TL;DR: This paper proposes a new set of benchmarks and evaluation methods for the next generation of optical flow algorithms and analyzes the results obtained to date to draw a large number of conclusions.
Abstract: The quantitative evaluation of optical flow algorithms by Barron et al. (1994) led to significant advances in performance. The challenges for optical flow algorithms today go beyond the datasets and evaluation methods proposed in that paper. Instead, they center on problems associated with complex natural scenes, including nonrigid motion, real sensor noise, and motion discontinuities. We propose a new set of benchmarks and evaluation methods for the next generation of optical flow algorithms. To that end, we contribute four types of data to test different aspects of optical flow algorithms: (1) sequences with nonrigid motion where the ground-truth flow is determined by tracking hidden fluorescent texture, (2) realistic synthetic sequences, (3) high frame-rate video used to study interpolation error, and (4) modified stereo sequences of static scenes. In addition to the average angular error used by Barron et al., we compute the absolute flow endpoint error, measures for frame interpolation error, improved statistics, and results at motion discontinuities and in textureless regions. In October 2007, we published the performance of several well-known methods on a preliminary version of our data to establish the current state of the art. We also made the data freely available on the web at http://vision.middlebury.edu/flow/ . Subsequently a number of researchers have uploaded their results to our website and published papers using the data. A significant improvement in performance has already been achieved. In this paper we analyze the results obtained to date and draw a large number of conclusions from them.

2,534 citations

Journal ArticleDOI
TL;DR: The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden, finding that CVDs remain a major cause of health loss for all regions of the world.

2,525 citations

Journal ArticleDOI
TL;DR: A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore, a unique analytical capability that makes inexpensive, rapid DNA sequencing a possibility.
Abstract: A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. The nanopore provides a highly confined space within which single nucleic acid polymers can be analyzed at high throughput by one of a variety of means, and the perfect processivity that can be enforced in a narrow pore ensures that the native order of the nucleobases in a polynucleotide is reflected in the sequence of signals that is detected. Kilobase length polymers (single-stranded genomic DNA or RNA) or small molecules (e.g., nucleosides) can be identified and characterized without amplification or labeling, a unique analytical capability that makes inexpensive, rapid DNA sequencing a possibility. Further research and development to overcome current challenges to nanopore identification of each successive nucleotide in a DNA strand offers the prospect of 'third generation' instruments that will sequence a diploid mammalian genome for ∼$1,000 in ∼24 h.

2,512 citations


Authors

Showing all 36143 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Robert Langer2812324326306
Robert M. Califf1961561167961
Eric J. Topol1931373151025
Joan Massagué189408149951
Joseph Biederman1791012117440
Gonçalo R. Abecasis179595230323
James F. Sallis169825144836
Steven N. Blair165879132929
Charles M. Lieber165521132811
J. S. Lange1602083145919
Christopher J. O'Donnell159869126278
Charles M. Perou156573202951
David J. Mooney15669594172
Richard J. Davidson15660291414
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023126
2022591
20215,549
20205,321
20194,806
20184,462