Bulgarian Academy of Sciences

About: Bulgarian Academy of Sciences is a government organization based out in Sofia, Bulgaria. It is known for research contribution in the topics: Catalysis & Coupling constant. The organization has 17989 authors who have published 36276 publications receiving 642820 citations. The organization is also known as: Bulgarian Academy of Sciences，簡稱：BAS & Balgarska Akademiya na Naukite.

Hairy root type plant in vitro systems as sources of bioactive substances

Abstract: "Hairy root" systems, obtained by transforming plant tissues with the "natural genetic engineer" Agrobacterium rhizogenes, have been known for more than three decades. To date, hairy root cultures have been obtained from more than 100 plant species, including several endangered medicinal plants, affording opportunities to produce important phytochemicals and proteins in eco-friendly conditions. Diverse strategies can be applied to improve the yields of desired metabolites and to produce recombinant proteins. Furthermore, recent advances in bioreactor design and construction allow hairy root-based technologies to be scaled up while maintaining their biosynthetic potential. This review highlights recent progress in the field and outlines future prospects for exploiting the potential utility of hairy root cultures as "chemical factories" for producing bioactive substances.

Gram-scale synthesis of monodisperse gold colloids by the solvated metal atom dispersion method and digestive ripening and their organization into two- and three-dimensional structures.

Abstract: We describe a synthetic procedure for preparation of large quantities of monodisperse thiol-stabilized gold colloids in toluene solution. The method is based on the solvated metal atom dispersion technique (SMAD), which is very suitable for preparation of large amounts of metal colloidal solutions, as well as of metal sulfide, metal oxide, and other types of dispersed compounds in different solvents. A combination of two different solvents like acetone and toluene is used for the preparation of the gold colloids. The necessity of initially carrying out the SMAD reaction in acetone comes from its high degree of solvation of gold particles. Acetone acts as a preliminary stabilizing agent. After its removal from the system, the particles are stabilized by dodecanethiol molecules, which enable their very good dispersion in toluene solution. A digestive ripening procedure is carried out with the gold−toluene colloid, and for this purpose pure toluene as solvent is necessary. This has a dramatic effect on the n...

Antioxidant activity and phenolic content of betalain extracts from intact plants and hairy root cultures of the red beetroot Beta vulgaris cv. Detroit dark red.

Abstract: Betalains are water-soluble plant pigments that are widely used as food colorants, and have a wide range of desirable biological activities, including antioxidant, anti-inflammatory, hepatoprotective, anti-cancer properties. They can be produced from various plants, notably beetroot, but betalain products obtained in this way also have some undesirable properties and are difficult to standardize. A potentially attractive alternative is to use hairy root cultures. In the study reported here, we found that betalain extracts obtained from hairy root cultures of the red beetroot B. vulgaris cv. Detroit Dark Red also had higher antioxidant activity than extracts obtained from mature beetroots: six-fold higher 2,2-dyphenyl-1-picrylhydrazyl radical scavenging ability (90.7% inhibition, EC(50) = 0.11 mg, vs 14.2% inhibition, EC(50) = 0.70 mg) and 3.28-fold higher oxygen radical absorbance capacity (4,100 microM TE/g dry extract, vs 1,250 microM TE/g dry extract). The high antioxidant activity of the hairy root extracts was associated with increased concentrations (more than 20-fold) of total phenolic concomitant compounds, which may have synergistic effects with betalains. The presence of 4-hydroxybenzoic acid, caffeic acid, catechin hydrate, and epicatechin were detected in both types of extract, but at different concentrations. Rutin was only present at high concentration (1.096 mg.g(-1) dry extract) in betalain extracts from the hairy root cultures, whereas chlorogenic acid was only detected at measurable concentrations in extracts from intact plants.

Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s=8 Tev

Abstract: A search for new physics is performed in multijet events with large missing transverse momentum produced in proton-proton collisions at sqrt(s)=8 TeV using a data sample corresponding to an integrated luminosity of 19.5 inverse femtobarns collected with the CMS detector at the LHC. The data sample is divided into three jet multiplicity categories (3-5, 6-7, and 8 or more jets), and studied further in bins of two variables: the scalar sum of jet transverse momenta and the missing transverse momentum. The observed numbers of events in various categories are consistent with backgrounds expected from standard model processes. Exclusion limits are presented for several simplified supersymmetric models of squark or gluino pair production.

Fast and ultrafast Kelvin wave modulations of the equatorial evening F region vertical drift and spread F development

Abstract: In this paper, we investigate the role of eastward and upward propagating fast (FK) and ultrafast Kelvin (UFK) waves in the day-to-day variability of equatorial evening prereversal vertical drift and post sunset generation of spread F/plasma bubble irregularities. Meteor wind data from Cariri and Cachoeira Paulista (Brazil) and medium frequency (MF) radar wind data from Tirunelveli (India) are analyzed together with Thermosphere-Ionosphere-Mesosphere Energetics and Dynamics/Sounding of the Atmosphere using Broadband Emission Radiometry (TIMED/SABER) temperature in the 40- to 100-km region to characterize the zonal and vertical propagations of these waves. Also analyzed are the F region evening vertical drift and spread F (ESF) development features as diagnosed by Digisonde (Lowell Digisonde International, LLC, Lowell, MA, USA) operated at Fortaleza and Sao Luis in Brazil. The SABER temperature data permitted determination of the upward propagation characteristics of the FK (E1) waves with propagation speed in the range of 4 km/day. The radar mesosphere and lower thermosphere (MLT) winds in the widely separated longitude sectors have yielded the eastward phase velocity of both the FK and UFK waves. The vertical propagation of these waves cause strong oscillation in the F region evening prereversal vertical drift, observed for the first time at both FK and UFK periodicities. A delay of a few (approximately 10) days is observed in the F region vertical drift perturbation with respect to the corresponding FK/UFK zonal wind oscillations, or temperature oscillations in the MLT region, which has permitted a direct identification of the sunset electrodynamic coupling process as being responsible for the generation of the FK/UFK-induced vertical drift oscillation. The vertical drift oscillations are found to cause significant modulation in the spread F/plasma bubble irregularity development. The overall results highlight the role of FK/UFK waves in the day-to-day variability of the ESF in its occurrence season.