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Institution

California Institute of Technology

EducationPasadena, California, United States
About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.


Papers
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Journal ArticleDOI
TL;DR: The use of Python has become the de facto standard for exploratory, interactive, and computation-driven scientific research as mentioned in this paper, and several of the core Python libraries and tools used in scientific research have been discussed.
Abstract: Python has arguably become the de facto standard for exploratory, interactive, and computation-driven scientific research. This issue discusses Python's advantages for scientific research and presents several of the core Python libraries and tools used in scientific research.

1,240 citations

Journal ArticleDOI
TL;DR: This framework offers a coherent scheme for explaining the neural correlates of (visual) consciousness in terms of competing cellular assemblies and outlines some general experimental approaches to the problem.
Abstract: Here we summarize our present approach to the problem of consciousness. After an introduction outlining our general strategy, we describe what is meant by the term 'framework' and set it out under ten headings. This framework offers a coherent scheme for explaining the neural correlates of (visual) consciousness in terms of competing cellular assemblies. Most of the ideas we favor have been suggested before, but their combination is original. We also outline some general experimental approaches to the problem and, finally, acknowledge some relevant aspects of the brain that have been left out of the proposed framework.

1,238 citations

Journal ArticleDOI
TL;DR: In this article, an analysis is made of the rocking motion of structures of inverted pendulum type during the Chilean earthquakes of May, 1960, and it is shown that there is a scale effect which makes tall slender structures more stable against overturning than might have been expected.
Abstract: During the Chilean earthquakes of May, 1960, a number of tall, slender structures survived the ground shaking whereas more stable appearing structures were severely damaged. An analysis is made of the rocking motion of structures of inverted pendulum type. It is shown that there is a scale effect which makes tall slender structures more stable against overturning than might have been expected, and, therefore, the survival of such structures during earthquakes is not surprising.

1,237 citations

Journal ArticleDOI
TL;DR: In this paper, the authors examined the infrared (IR) 3-500μm spectral energy distributions (SEDs) of galaxies at 0 < z < 2.5, supplemented by a local reference sample from IRAS, ISO, Spitzer, and AKARI data.
Abstract: We present the deepest 100 to 500 μm far-infrared observations obtained with the Herschel Space Observatory as part of the GOODS-Herschel key program, and examine the infrared (IR) 3–500 μm spectral energy distributions (SEDs) of galaxies at 0 < z < 2.5, supplemented by a local reference sample from IRAS, ISO, Spitzer, and AKARI data. We determine the projected star formation densities of local galaxies from their radio and mid-IR continuum sizes. We find that the ratio of total IR luminosity to rest-frame 8 μm luminosity, IR8 (≡ L_(IR)^(tot)/L_8), follows a Gaussian distribution centered on IR8 = 4 (σ = 1.6) and defines an IR main sequence for star-forming galaxies independent of redshift and luminosity. Outliers from this main sequence produce a tail skewed toward higher values of IR8. This minority population ( 3 × 10^(10) L_⊙ kpc^(-2)) and a high specific star formation rate (i.e., starbursts). The rest-frame, UV-2700 A size of these distant starbursts is typically half that of main sequence galaxies, supporting the correlation between star formation density and starburst activity that is measured for the local sample. Locally, luminous and ultraluminous IR galaxies, (U)LIRGs (L_(IR)^(tot)≥ 10^(11) L_☉), are systematically in the starburst mode, whereas most distant (U)LIRGs form stars in the “normal” main sequence mode. This confusion between two modes of star formation is the cause of the so-called “mid-IR excess” population of galaxies found at z > 1.5 by previous studies. Main sequence galaxies have strong polycyclic aromatic hydrocarbon (PAH) emission line features, a broad far-IR bump resulting from a combination of dust temperatures (T_(dust) ~ 15–50 K), and an effective T_(dust) ~ 31 K, as derived from the peak wavelength of their infrared SED. Galaxies in the starburst regime instead exhibit weak PAH equivalent widths and a sharper far-IR bump with an effective T_(dust)~ 40 K. Finally, we present evidence that the mid-to-far IR emission of X-ray active galactic nuclei (AGN) is predominantly produced by star formation and that candidate dusty AGNs with a power-law emission in the mid-IR systematically occur in compact, dusty starbursts. After correcting for the effect of starbursts on IR8, we identify new candidates for extremely obscured AGNs.

1,235 citations

Journal ArticleDOI
TL;DR: The molecular mechanisms that control mitochondrial dynamics, and why are they important for mitochondrial function are reviewed and how defects in mitochondrial dynamics might cause neuronal disease is explored.
Abstract: Recent findings have sparked renewed appreciation for the remarkably dynamic nature of mitochondria. These organelles constantly fuse and divide, and are actively transported to specific subcellular locations. These dynamic processes are essential for mammalian development, and defects lead to neurodegenerative disease. But what are the molecular mechanisms that control mitochondrial dynamics, and why are they important for mitochondrial function? We review these issues and explore how defects in mitochondrial dynamics might cause neuronal disease.

1,234 citations


Authors

Showing all 58155 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Donald P. Schneider2421622263641
George M. Whitesides2401739269833
Yi Chen2174342293080
David Baltimore203876162955
Edward Witten202602204199
George Efstathiou187637156228
Michael A. Strauss1851688208506
Jing Wang1844046202769
Ruedi Aebersold182879141881
Douglas Scott1781111185229
Hyun-Chul Kim1764076183227
Phillip A. Sharp172614117126
Timothy M. Heckman170754141237
Zhenan Bao169865106571
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023176
2022737
20214,682
20205,519
20195,321
20185,133