California Institute of Technology

About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.

The Star Formation Rate and Dense Molecular Gas in Galaxies

Abstract: HCN luminosity is a tracer of dense molecular gas, n(H(2)) greater than or similar to3 x 10(4) cm(-3), associated with star-forming giant molecular cloud (GMC) cores. We present the results and analysis of our survey of HCN emission from 65 infrared galaxies, including nine ultraluminous infrared galaxies (ULIGs, L(IR) greater than or similar to 10(12) L(circle dot)), 22 luminous infrared galaxies (LIGs, 10(11) L(circle dot) < L(IR) less than or similar to 10(12) L(circle dot)), and 34 normal spiral galaxies with lower IR luminosity (most are large spiral galaxies). We have measured the global HCN line luminosity, and the observations are reported in Paper I. This paper analyzes the relationships between the total far-IR luminosity (a tracer of the star formation rate), the global HCN line luminosity (a measure of the total dense molecular gas content), and the CO luminosity (a measure of the total molecular content). We find a tight linear correlation between the IR and HCN luminosities L(IR) and L(HCN) (in the log-log plot) with a correlation coefficient R = 0.94, and an almost constant average ratio L(IR)/L(HCN) = 900 L(circle dot) (K km s(-1) pc(2))(-1). The IR-HCN linear correlation is valid over 3 orders of magnitude including ULIGs, the most luminous objects in the local universe. The direct consequence of the linear IR-HCN correlation is that the star formation law in terms of dense molecular gas content has a power-law index of 1.0. The global star formation rate is linearly proportional to the mass of dense molecular gas in normal spiral galaxies, LIGs, and ULIGs. This is strong evidence in favor of star formation as the power source in ultraluminous galaxies since the star formation in these galaxies appears to be normal and expected given their high mass of dense star-forming molecular gas.

MicroRNAs: new regulators of immune cell development and function.

Abstract: Decades of research went into understanding immune cell development and function without awareness that consideration of a key element, microRNA (miRNA), was lacking. The discovery of miRNAs as regulators of developmental events in model organisms suggested to many investigators that miRNA might be involved in the immune system. In the past few years, widespread examination of this possibility has produced notable results. Results have shown that miRNAs affect mammalian immune cell differentiation, the outcome of immune responses to infection and the development of diseases of immunological origin. Some miRNAs repress expression of target proteins with well established functions in hematopoiesis. Here we bring together much of this work, which has so far only scratched the surface of this very fertile field of investigation, and show how the results illuminate many historic questions about hematopoiesis and immune function.

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes.

Abstract: The neuron-restrictive silencer factor (NRSF) binds a DNA sequence element, called the neuron-restrictive silencer element (NRSE), that represses neuronal gene transcription in nonneuronal cells. Consensus NRSEs have been identified in 18 neuron-specific genes. Complementary DNA clones encoding a functional fragment of NRSF were isolated and found to encode a novel protein containing eight noncanonical zinc fingers. Expression of NRSF mRNA was detected in most nonneuronal tissues at several developmental stages. In the nervous system, NRSF mRNA was detected in undifferentiated neuronal progenitors, but not in differentiated neurons. NRSF represents the first example of a vertebrate silencer protein that potentially regulates a large battery of cell type-specific genes, and therefore may function as a master negative regulator of neurogenesis.

The Kinematics of the Ultra-faint Milky Way Satellites: Solving the Missing Satellite Problem

Abstract: We present Keck DEIMOS spectroscopy of stars in eight of the newly discovered ultra-faint dwarf galaxies around the Milky Way. We measure the velocity dispersions of Canes Venatici I, Canes Venatici II, Coma Berenices, Hercules, Leo IV, Leo T, Ursa Major I, and Ursa Major II from the velocities of 18-214 stars in each galaxy and find dispersions ranging from 3.3 to 7.6 km s^(-1). The six galaxies with absolute magnitudes M_V < -4 are highly dark matter dominated, with mass-to-light ratios approaching 1000 M_☉/L_(☉,V). For the fainter galaxies we find tentative evidence for tidal disruption. The measured velocity dispersions of the ultra-faint dwarfs are correlated with their luminosities, indicating that a minimum mass for luminous galactic systems may not yet have been reached. We also measure the metallicities of the observed stars and find that the new dwarfs have mean metallicities of [Fe/H] = -2.0 to -2.3; these galaxies represent some of the most metal-poor stellar systems known. The six brightest of the ultra-faint dwarfs extend the luminosity-metallicity relationship followed by more luminous dwarfs by a factor of ~30 in luminosity. We detect metallicity spreads of up to 0.5 dex in several objects, suggesting multiple star formation epochs. UMa II and Com, despite their exceptionally low luminosities, have higher metallicities that suggest they may once have been much more massive. Having established the masses of the ultra-faint dwarfs, we re-examine the missing satellite problem. After correcting for the sky coverage of the Sloan Digital Sky Survey, we find that the ultra-faint dwarfs substantially alleviate the discrepancy between the predicted and observed numbers of satellites around the Milky Way, but there are still a factor of ~4 too few dwarf galaxies over a significant range of masses. We show that if galaxy formation in low-mass dark matter halos is strongly suppressed after reionization, the simulated circular velocity function of CDM subhalos can be brought into approximate agreement with the observed circular velocity function of Milky Way satellite galaxies.

Techniques for analyzing frequency selective surfaces-a review

Abstract: A number of representative techniques for analyzing frequency-selective surfaces (FSSs), which comprise periodic arrays of patches or apertures in a conducting screen and find important applications as filters in microwaves and optics, are discussed. The basic properties of the FSSs are reviewed and several different approaches to predicting their frequency-response characteristics are described. Some recent developments in the treatment of truncated, curved, and doubly periodic screens are mentioned and representative experimental results are included. >