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Institution

California Institute of Technology

EducationPasadena, California, United States
About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.


Papers
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Journal ArticleDOI
TL;DR: By enabling content mixing between mitochondria, fusion and fission serve to maintain a homogeneous and healthy mitochondrial population and lead to improvements in human health.
Abstract: Mitochondria are dynamic organelles that continually undergo fusion and fission. These opposing processes work in concert to maintain the shape, size, and number of mitochondria and their physiological function. Some of the major molecules mediating mitochondrial fusion and fission in mammals have been discovered, but the underlying molecular mechanisms are only partially unraveled. In particular, the cast of characters involved in mitochondrial fission needs to be clarified. By enabling content mixing between mitochondria, fusion and fission serve to maintain a homogeneous and healthy mitochondrial population. Mitochondrial dynamics has been linked to multiple mitochondrial functions, including mitochondrial DNA stability, respiratory capacity, apoptosis, response to cellular stress, and mitophagy. Because of these important functions, mitochondrial fusion and fission are essential in mammals, and even mild defects in mitochondrial dynamics are associated with disease. A better understanding of these processes likely will ultimately lead to improvements in human health.

958 citations

Journal ArticleDOI
TL;DR: In this paper, it was shown that there is a finite gap between the mutual information obtainable by a joint measurement on these states and a measurement in which only local actions are permitted.
Abstract: We exhibit an orthogonal set of product states of two three-state particles that nevertheless cannot be reliably distinguished by a pair of separated observers ignorant of which of the states has been presented to them, even if the observers are allowed any sequence of local operations and classical communication between the separate observers. It is proved that there is a finite gap between the mutual information obtainable by a joint measurement on these states and a measurement in which only local actions are permitted. This result implies the existence of separable superoperators that cannot be implemented locally. A set of states are found involving three two-state particles that also appear to be nonmeasurable locally. These and other multipartite states are classified according to the entropy and entanglement costs of preparing and measuring them by local operations.

957 citations

Journal ArticleDOI
TL;DR: In this article, the authors show that a large fraction of the weak afterglow observations are also due to the common occurrence of beaming in GRBs, and that their jets have already transitioned to the spreading phase before the first afterglove observations were made.
Abstract: In several GRBs afterglows, rapid temporal decay is observed which is inconsistent with spherical (isotropic) blast-wave models. In particular, GRB 980519 had the most rapidly fading of the well-documented GRB afterglows, with t^{-2.05\pm 0.04} in optical as well as in X-rays. We show that such temporal decay is more consistent with the evolution of a jet after it slows down and spreads laterally, for which t^{-p} decay is expected (where p is the index of the electron energy distribution). Such a beaming model would relax the energy requirements on some of the more extreme GRBs by a factor of several hundreds. It is likely that a large fraction of the weak (or no) afterglow observations are also due to the common occurrence of beaming in GRBs, and that their jets have already transitioned to the spreading phase before the first afterglow observations were made. With this interpretation, a universal value of p~2.5 is consistent with all data.

957 citations

Journal ArticleDOI
23 Jun 2011-Neuron
TL;DR: This work attempts to identify common themes in experiments with human participants and with animal models which suggest roles that the areas play in learning about reward associations, selecting reward goals, choosing actions to obtain reward, and monitoring the potential value of switching to alternative courses of action.

957 citations

Journal ArticleDOI
TL;DR: In this article, the radio counterparts to the IRAS Redshift Survey galaxies are identified in the NRAO VLA Sky Survey (NVSS) catalog, and their radio and far-IR properties of galaxies in the local volume are used directly to infer the extinction-free star formation rate.
Abstract: The radio counterparts to the IRAS Redshift Survey galaxies are identified in the NRAO VLA Sky Survey (NVSS) catalog. Our new catalog of the IR flux-limited (S60 μm ≥ 2 Jy) complete sample of 1809 galaxies lists accurate radio positions, redshifts, and 1.4 GHz radio and IRAS fluxes. This sample is 6 times larger in size and 5 times deeper in redshift coverage (to z ≈ 0.15) than those used in earlier studies of the radio and far-IR (FIR) properties of galaxies in the local volume. The well-known radio-FIR correlation is obeyed by the overwhelming majority (≥98%) of the IR-selected galaxies, and the radio AGNs identified by their excess radio emission constitute only about 1% of the sample, independent of the IR luminosity. These FIR-selected galaxies can account for the entire population of late-type field galaxies in the local volume, and their radio continuum may be used directly to infer the extinction-free star formation rate in most cases. Both the 1.4 GHz radio and 60 μm IR luminosity functions are reasonably well described by linear sums of two Schechter functions, one representing normal, late-type field galaxies and the other representing starbursts and other luminous IR galaxies. The integrated FIR luminosity density for the local volume is (4.8 ± 0.5) × 107 L☉ Mpc-3, less than 10% of which is contributed by the luminous IR galaxies with LFIR ≥ 1011 L☉. The inferred extinction-free star formation density for the local volume is 0.015 ± 0.005 M☉ yr-1 Mpc-3.

955 citations


Authors

Showing all 58155 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Donald P. Schneider2421622263641
George M. Whitesides2401739269833
Yi Chen2174342293080
David Baltimore203876162955
Edward Witten202602204199
George Efstathiou187637156228
Michael A. Strauss1851688208506
Jing Wang1844046202769
Ruedi Aebersold182879141881
Douglas Scott1781111185229
Hyun-Chul Kim1764076183227
Phillip A. Sharp172614117126
Timothy M. Heckman170754141237
Zhenan Bao169865106571
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023176
2022737
20214,682
20205,519
20195,321
20185,133