California Institute of Technology

About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.

Marketing actions can modulate neural representations of experienced pleasantness

Abstract: Despite the importance and pervasiveness of marketing, almost nothing is known about the neural mechanisms through which it affects decisions made by individuals. We propose that marketing actions, such as changes in the price of a product, can affect neural representations of experienced pleasantness. We tested this hypothesis by scanning human subjects using functional MRI while they tasted wines that, contrary to reality, they believed to be different and sold at different prices. Our results show that increasing the price of a wine increases subjective reports of flavor pleasantness as well as blood-oxygen-level-dependent activity in medial orbitofrontal cortex, an area that is widely thought to encode for experienced pleasantness during experiential tasks. The paper provides evidence for the ability of marketing actions to modulate neural correlates of experienced pleasantness and for the mechanisms through which the effect operates.

Decline in Arctic sea ice thickness from submarine and ICESat records: 1958–2008

Abstract: [1] The decline of sea ice thickness in the Arctic Ocean from ICESat (2003–2008) is placed in the context of estimates from 42 years of submarine records (1958–2000) described by Rothrock et al. (1999, 2008). While the earlier 1999 work provides a longer historical record of the regional changes, the latter offers a more refined analysis, over a sizable portion of the Arctic Ocean supported by a much stronger and richer data set. Within the data release area (DRA) of declassified submarine sonar measurements (covering ∼38% of the Arctic Ocean), the overall mean winter thickness of 3.64 m in 1980 can be compared to a 1.89 m mean during the last winter of the ICESat record—an astonishing decrease of 1.75 m in thickness. Between 1975 and 2000, the steepest rate of decrease is −0.08 m/yr in 1990 compared to a slightly higher winter/summer rate of −0.10/−0.20 m/yr in the five-year ICESat record (2003–2008). Prior to 1997, ice extent in the DRA was >90% during the summer minimum. This can be contrasted to the gradual decrease in the early 2000s followed by an abrupt drop to <55% during the record setting minimum in 2007. This combined analysis shows a long-term trend of sea ice thinning over submarine and ICESat records that span five decades.

Formation of Urban Fine Particulate Matter

Abstract: Urban air pollution represents one of the greatest environmental challenges facing mankind in the 21st century. Noticeably, many developing countries, such as China and India, have experienced severe air pollution because of their fast-developing economy and urbanization. Globally, the urbanization trend is projected to continue: 70% of the world population will reside in urban centers by 2050, and there will exist 41 megacities (with more than 10 million inhabitants) by 2030. Air pollutants consist of a complex combination of gases and particulate matter (PM). In particular, fine PM (particles with the aerodynamic diameter smaller than 2.5 μm or PM_(2.5)) profoundly impacts human health, visibility, the ecosystem, the weather, and the climate, and these PM effects are largely dependent on the aerosol properties, including the number concentration, size, and chemical composition. PM is emitted directly into the atmosphere (primary) or formed in the atmosphere through gas-to-particle conversion (secondary) (Figure 1). Also, primary and secondary PM undergoes chemical and physical transformations and is subjected to transport, cloud processing, and removal from the atmosphere.

Guidelines and definitions for research on epithelial–mesenchymal transition

Abstract: Epithelial-mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range of physiological and pathological conditions and is driven by a conserved set of inducing signals, transcriptional regulators and downstream effectors. With over 5,700 publications indexed by Web of Science in 2019 alone, research on EMT is expanding rapidly. This growing interest warrants the need for a consensus among researchers when referring to and undertaking research on EMT. This Consensus Statement, mediated by 'the EMT International Association' (TEMTIA), is the outcome of a 2-year-long discussion among EMT researchers and aims to both clarify the nomenclature and provide definitions and guidelines for EMT research in future publications. We trust that these guidelines will help to reduce misunderstanding and misinterpretation of research data generated in various experimental models and to promote cross-disciplinary collaboration to identify and address key open questions in this research field. While recognizing the importance of maintaining diversity in experimental approaches and conceptual frameworks, we emphasize that lasting contributions of EMT research to increasing our understanding of developmental processes and combatting cancer and other diseases depend on the adoption of a unified terminology to describe EMT.

Migrations and dynamics of the intertropical convergence zone

Abstract: Rainfall on Earth is most intense in the intertropical convergence zone (ITCZ), a narrow belt of clouds centred on average around six degrees north of the Equator. The mean position of the ITCZ north of the Equator arises primarily because the Atlantic Ocean transports energy northward across the Equator, rendering the Northern Hemisphere warmer than the Southern Hemisphere. On seasonal and longer timescales, the ITCZ migrates, typically towards a warming hemisphere but with exceptions, such as during El Nino events. An emerging framework links the ITCZ to the atmospheric energy balance and may account for ITCZ variations on timescales from years to geological epochs.