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Institution

California Institute of Technology

EducationPasadena, California, United States
About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the final results of the Hubble Space Telescope (HST) Key Project to measure the Hubble constant are presented, and the results are based on a Cepheid calibration of several secondary distance methods applied over the range of about 60-400 Mpc.
Abstract: We present here the final results of the Hubble Space Telescope (HST) Key Project to measure the Hubble constant. We summarize our method, the results, and the uncertainties, tabulate our revised distances, and give the implications of these results for cosmology. Our results are based on a Cepheid calibration of several secondary distance methods applied over the range of about 60-400 Mpc. The analysis presented here benefits from a number of recent improvements and refinements, including (1) a larger LMC Cepheid sample to define the fiducial period-luminosity (PL) relations, (2) a more recent HST Wide Field and Planetary Camera 2 (WFPC2) photometric calibration, (3) a correction for Cepheid metallicity, and (4) a correction for incompleteness bias in the observed Cepheid PL samples. We adopt a distance modulus to the LMC (relative to which the more distant galaxies are measured) of μ0 = 18.50 ± 0.10 mag, or 50 kpc. New, revised distances are given for the 18 spiral galaxies for which Cepheids have been discovered as part of the Key Project, as well as for 13 additional galaxies with published Cepheid data. The new calibration results in a Cepheid distance to NGC 4258 in better agreement with the maser distance to this galaxy. Based on these revised Cepheid distances, we find values (in km s-1 Mpc-1) of H0 = 71 ± 2 ± 6 (systematic) (Type Ia supernovae), H0 = 71 ± 3 ± 7 (Tully-Fisher relation), H0 = 70 ± 5 ± 6 (surface brightness fluctuations), H0 = 72 ± 9 ± 7 (Type II supernovae), and H0 = 82 ± 6 ± 9 (fundamental plane). We combine these results for the different methods with three different weighting schemes, and find good agreement and consistency with H0 = 72 ± 8 km s-1 Mpc-1. Finally, we compare these results with other, global methods for measuring H0.

3,397 citations

Journal ArticleDOI
TL;DR: In this article, a statistical comparison of earthquake frequency in California with that of the world as a whole was made by comparing the historical record of the earthquake frequency of California with the global average.
Abstract: Estimates of the frequency of destructive shocks in California have usually been based on the very imperfect historical record. The present note attempts to revise these estimates by statistical comparison of earthquake frequency in California with that of the world as a whole.

3,396 citations

Journal ArticleDOI
TL;DR: Pure virus lines were established by isolating the virus population produced in single plaques, which had the same morphological, serological, and pathogenic properties as the parent strain.
Abstract: Plaques have been produced with the three types of poliomyelitis viruses on monolayer tissue cultures of monkey kidney and monkey testis. The number of plaques was proportional to the concentration of the virus. Each plaque originates, therefore, from a single virus particle, defined as the virus unit that is unseparable by dilution. The plaques are due to the specific action of the virus since they are suppressed by type-specific antiserum. Pure virus lines were established by isolating the virus population produced in single plaques. These derived virus lines had the same morphological, serological, and pathogenic properties as the parent strain. High titer virus stocks, with titers up to 7 x 10(8) plaque-forming particles per ml., were obtained.

3,394 citations

Journal ArticleDOI
TL;DR: In this article, the authors describe a new and highly effective optical frequency discriminator and laser stabilization system based on signals reflected from a stable Fabry-Perot reference interferometer.
Abstract: We describe a new and highly effective optical frequency discriminator and laser stabilization system based on signals reflected from a stable Fabry-Perot reference interferometer. High sensitivity for detection of resonance information is achieved by optical heterodyne detection with sidebands produced by rf phase modulation. Physical, optical, and electronic aspects of this discriminator/laser frequency stabilization system are considered in detail. We show that a high-speed domain exists in which the system responds to the phase (rather than frequency) change of the laser; thus with suitable design the servo loop bandwidth is not limited by the cavity response time. We report diagnostic experiments in which a dye laser and gas laser were independently locked to one stable cavity. Because of the precautions employed, the observed sub-100 Hz beat line width shows that the lasers were this stable. Applications of this system of laser stabilization include precision laser spectroscopy and interferometric gravity-wave detectors.

3,393 citations

Journal ArticleDOI
TL;DR: High-density recordings of field activity in animals and subdural grid recordings in humans can provide insight into the cooperative behaviour of neurons, their average synaptic input and their spiking output, and can increase the understanding of how these processes contribute to the extracellular signal.
Abstract: Neuronal activity in the brain gives rise to transmembrane currents that can be measured in the extracellular medium. Although the major contributor of the extracellular signal is the synaptic transmembrane current, other sources — including Na+ and Ca2+ spikes, ionic fluxes through voltage- and ligand-gated channels, and intrinsic membrane oscillations — can substantially shape the extracellular field. High-density recordings of field activity in animals and subdural grid recordings in humans, combined with recently developed data processing tools and computational modelling, can provide insight into the cooperative behaviour of neurons, their average synaptic input and their spiking output, and can increase our understanding of how these processes contribute to the extracellular signal.

3,366 citations


Authors

Showing all 58155 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Donald P. Schneider2421622263641
George M. Whitesides2401739269833
Yi Chen2174342293080
David Baltimore203876162955
Edward Witten202602204199
George Efstathiou187637156228
Michael A. Strauss1851688208506
Jing Wang1844046202769
Ruedi Aebersold182879141881
Douglas Scott1781111185229
Hyun-Chul Kim1764076183227
Phillip A. Sharp172614117126
Timothy M. Heckman170754141237
Zhenan Bao169865106571
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023176
2022737
20214,682
20205,519
20195,321
20185,133