California State University, Long Beach

About: California State University, Long Beach is a education organization based out in Long Beach, California, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 10036 authors who have published 13933 publications receiving 377394 citations. The organization is also known as: Cal State Long Beach & Long Beach State.

Mathematical analysis of the quasilinear effects in a hyperbolic model blood flow through compliant axi-symmetric vessels

Abstract: In this paper, we present a mathematical analysis of the quasilinear effects arising in a hyperbolic system of partial differential equations modelling blood flow through large compliant vessels. The equations are derived using asymptotic reduction of the incompressible Navier–Stokes equations in narrow, long channels. To guarantee strict hyperbolicity we first derive the estimates on the initial and boundary data which imply strict hyperbolicity in the region of smooth flow. We then prove a general theorem which provides conditions under which an initial–boundary value problem for a quasilinear hyperbolic system admits a smooth solution. Using this result we show that pulsatile flow boundary data always give rise to shock formation (high gradients in the velocity and inner vessel radius). We estimate the time and the location of the first shock formation and show that in a healthy individual, shocks form well outside the physiologically interesting region (2.8m downstream from the inlet boundary). In the end we present a study of the influence of vessel tapering on shock formation. We obtain a surprising result: vessel tapering postpones shock formation. We provide an explanation for why this is the case. Copyright © 2003 John Wiley & Sons, Ltd.

Megestrol acetate in cancer anorexia and weight loss.

Abstract: High-dose megestrol acetate has been associated with increased appetite and weight. To examine the effects of high-dose megestrol acetate in the treatment of anorexia and weight loss in patients with advanced hormone-insensitive malignant lesions, a randomized double-blind placebo-controlled trial was conducted. Patients receiving megestrol acetate for 1 month reported a significant improvement in appetite and adequacy of food intake compared with those receiving placebo. A three-item scale measuring appetite, adequacy of food intake, and concern about weight revealed a higher improvement with megestrol acetate than with placebo. Patients who worsened while receiving placebo had similar favorable changes after the cross over to megestrol acetate. These data indicate that megestrol acetate may improve appetite and food intake in patients with advanced cancer.

Tsunamis generated by subaerial mass flows

Abstract: [1] Tsunamis generated in lakes and reservoirs by subaerial mass flows pose distinctive problems for hazards assessment because the domain of interest is commonly the “near field,” beyond the zone of complex splashing but close enough to the source that wave propagation effects are not predominant. Scaling analysis of the equations governing water wave propagation shows that near-field wave amplitude and wavelength should depend on certain measures of mass flow dynamics and volume. The scaling analysis motivates a successful collapse (in dimensionless space) of data from two distinct sets of experiments with solid block “wave makers.” To first order, wave amplitude/water depth is a simple function of the ratio of dimensionless wave maker travel time to dimensionless wave maker volume per unit width. Wave amplitude data from previous laboratory investigations with both rigid and deformable wave makers follow the same trend in dimensionless parameter space as our own data. The characteristic wavelength/water depth for all our experiments is simply proportional to dimensionless wave maker travel time, which is itself given approximately by a simple function of wave maker length/water depth. Wave maker shape and rigidity do not otherwise influence wave features. Application of the amplitude scaling relation to several historical events yields “predicted” near-field wave amplitudes in reasonable agreement with measurements and observations. Together, the scaling relations for near-field amplitude, wavelength, and submerged travel time provide key inputs necessary for computational wave propagation and hazards assessment.

Crystalline Inorganic Frameworks with 56-Ring, 64-Ring, and 72-Ring Channels

Abstract: The development of zeolite-like structures with extra-large pores (>12-membered rings, 12R) has been sporadic and is currently at 30R. In general, templating via molecules leads to crystalline frameworks, whereas the use of organized assemblies that permit much larger pores produces noncrystalline frameworks. Synthetic methods that generate crystallinity from both discrete templates and organized assemblies represent a viable design strategy for developing crystalline porous inorganic frameworks spanning the micro and meso regimes. We show that by integrating templating mechanisms for both zeolites and mesoporous silica in a single system, the channel size for gallium zincophosphites can be systematically tuned from 24R and 28R to 40R, 48R, 56R, 64R, and 72R. Although the materials have low thermal stability and retain their templating agents, single-activator doping of Mn2+ can create white-light photoluminescence.