Institution
Carleton University
Education•Ottawa, Ontario, Canada•
About: Carleton University is a education organization based out in Ottawa, Ontario, Canada. It is known for research contribution in the topics: Population & Context (language use). The organization has 15852 authors who have published 39650 publications receiving 1106610 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Some recent advances in understanding the biochemical mechanisms of metabolic arrest are reviewed, with a focus on ideas such as the strategies used to reorganize metabolic priorities for ATP expenditure, molecular controls that suppress cell functions, and changes in gene expression that support hypometabolism.
Abstract: Entry into a hypometabolic state is an important survival strategy for many organisms when challenged by environmental stress, including low oxygen, cold temperatures and lack of food or water. The molecular mechanisms that regulate transitions to and from hypometabolic states, and stabilize long-term viability during dormancy, are proving to be highly conserved across phylogenic lines. A number of these mechanisms were identified and explored using anoxia-tolerant turtles as the model system, particularly from the research contributions made by Dr Peter L. Lutz in his explorations of the mechanisms of neuronal suppression in anoxic brain. Here we review some recent advances in understanding the biochemical mechanisms of metabolic arrest with a focus on ideas such as the strategies used to reorganize metabolic priorities for ATP expenditure, molecular controls that suppress cell functions (e.g. ion pumping, transcription, translation, cell cycle arrest), changes in gene expression that support hypometabolism, and enhancement of defense mechanisms (e.g. antioxidants, chaperone proteins, protease inhibitors) that stabilize macromolecules and promote long-term viability in the hypometabolic state.
245 citations
••
TL;DR: A simple four-compartment equilibrium distribution model suggested that the majority of BFRs being released into the environment would reside in soil and sediment and have localized distributions, and suggested that lower brominated congeners tend to be somewhat more mobile.
Abstract: The subcooled liquid vapor pressures (P0(L),25S) and aqueous solubilities (Sw,25s) were determined and Henry's law constants (H25s) were estimated for a number of brominated flame retardants (BFRs) at 25 degrees C. The established methods of the gas chromatography-retention time and generator column techniques were used to experimentally determine P0(L),25 and Sw,25 for hexabromobenzene and a series of brominated diphenyl ether (BDE) congeners. The H25 was estimated as the ratio of P0(L)25 to the subcooled liquid aqueous solubility. Values of PL0(L),25 obtained ranged from 0.000000282 Pa (BDE-190) to 0.259 Pa (BDE-3); Sw,25 ranged from 0.00000087 g/L (BDE-153 and BDE-154) to 0.00013 g/L (BDE-15); and H25 ranged from 0.0074 Pa m3/mol (BDE-183) to 21 Pa m3/mol (BDE-15). An increase in the bromine content of polybrominated diphenyl ether congeners resulted in significant decreases Of P0(L),25, Sw25, and H25. A simple four-compartment equilibrium distribution model suggested that the majority of BFRs being released into the environment would reside in soil and sediment and have localized distributions. The model also suggested that lower brominated congeners tend to be somewhat more mobile. Degradative debromination reactions that yield these congeners would mobilize them environmentally, and ultimately affect the fate and distribution of BFRs.
245 citations
••
TL;DR: This paper examined differences in the antecedents and consequences of work-family conflict, a form of interrole conflict that occurs when the demands of work and family are mutually incompatible in some respect.
Abstract: This research examines differences in the antecedents and consequences of work—family conflict — a form of interrole conflict that occurs when the demands of work and family are mutually incompatible in some respect — for two groups of career‐oriented men: those with a homemaker wife (called traditional‐career men) and those with a spouse in a career‐oriented job (labelled dual‐career men). Using a model built on the work of Kopelman, Greenhaus and Connolly (1983), the responses from 136 dual‐career men and 137 traditional‐career men were compared. The primary conclusion of this research is that maternal career employment has a significant effect on the antecedents of work — family conflict. Dual‐career men appear to experience a significant negative spillover from their work domain. We suggest that this spillover is due to a lack of structural flexibility in the workplace, outdated organizational policies that operate on the myth of separate worlds' and a lack of social support for the male dual‐career role which contradicts societal norms. Copyright
245 citations
••
TL;DR: Several important aspects of green ICN are identified, i.e., overview, energy efficiency metrics, network planning, enabling technologies, and challenges, including shutdown, slowdown, mobility, and cloud computing.
Abstract: Recently, a series of innovative information-centric networking (ICN) architectures have been designed to better address the shift from host-centric end-to-end communication to requester-driven content retrieval. With the explosive increase of mobile data traffic, the mobility issue in ICN is a growing concern and a number of approaches have been proposed to deal with the mobility problem in ICN. Despite the potential advantages of ICN in mobile wireless environments, several significant research challenges remain to be addressed before its widespread deployment, including consistent routing, local cached content discovery, energy efficiency, privacy, security and trust, and practical deployment. In this paper, we present a brief survey on some of the works that have already been done to achieve mobile ICN, and discuss some research issues and challenges. We identify several important aspects of mobile ICN: overview, mobility enabling technologies, information-centric wireless mobile networks, and research challenges.
245 citations
••
TL;DR: A number of frequency and time slot allocation techniques for enhancing the capacity and flexibility of TDMA-based systems are summarized, including slow random FH and slow frequency hopping.
Abstract: Time division multiple access (TDMA) is a classic approach to multiple access in digital cellular wireless communications systems. The authors summarize a number of frequency and time slot allocation techniques for enhancing the capacity and flexibility of TDMA-based systems. They also describe how the problems of fading, delay spread, time variability and interference affect TDMA systems, and how they may he countered and even exploited by appropriate techniques of detection, diversity, coding, adaptive equalization and slow frequency hopping (FH). It is worth emphasizing that the use of one of these techniques, slow random FH, results in a system that is in effect a hybrid of TDMA and code division multiple access (CDMA). >
245 citations
Authors
Showing all 16102 results
Name | H-index | Papers | Citations |
---|---|---|---|
George F. Koob | 171 | 935 | 112521 |
Zhenwei Yang | 150 | 956 | 109344 |
Andrew White | 149 | 1494 | 113874 |
J. S. Keller | 144 | 981 | 98249 |
R. Kowalewski | 143 | 1815 | 135517 |
Manuella Vincter | 131 | 944 | 122603 |
Gabriella Pasztor | 129 | 1401 | 86271 |
Beate Heinemann | 129 | 1085 | 81947 |
Claire Shepherd-Themistocleous | 129 | 1211 | 86741 |
Monica Dunford | 129 | 906 | 77571 |
Dave Charlton | 128 | 1065 | 81042 |
Ryszard Stroynowski | 128 | 1320 | 86236 |
Peter Krieger | 128 | 1171 | 81368 |
Thomas Koffas | 128 | 942 | 76832 |
Aranzazu Ruiz-Martinez | 126 | 783 | 71913 |