Carleton University

About: Carleton University is a education organization based out in Ottawa, Ontario, Canada. It is known for research contribution in the topics: Population & Context (language use). The organization has 15852 authors who have published 39650 publications receiving 1106610 citations.

Predicting global killer whale population collapse from PCB pollution

Abstract: Killer whales (Orcinus orca) are among the most highly polychlorinated biphenyl (PCB)-contaminated mammals in the world, raising concern about the health consequences of current PCB exposures. Using an individual-based model framework and globally available data on PCB concentrations in killer whale tissues, we show that PCB-mediated effects on reproduction and immune function threaten the long-term viability of >50% of the world's killer whale populations. PCB-mediated effects over the coming 100 years predicted that killer whale populations near industrialized regions, and those feeding at high trophic levels regardless of location, are at high risk of population collapse. Despite a near-global ban of PCBs more than 30 years ago, the world's killer whales illustrate the troubling persistence of this chemical class.

Performance by unified model analysis (PUMA)

Abstract: Evaluation of non-functional properties of a design (such as performance, dependability, security, etc.) can be enabled by design annotations specific to the property to be evaluated. Performance properties, for instance, can be annotated on UML designs by using the "UML Profile for Schedulability, Performance and Time (SPT)". However the communication between the design description in UML and the tools used for non-functional properties evaluation requires support, particularly for performance where there are many alternative performance analysis tools that might be applied. This paper describes a tool architecture called PUMA, which provides a unified interface between different kinds of design information and different kinds of performance models, for example Markov models, stochastic Petri nets and process algebras, queues and layered queues.The paper concentrates on the creation of performance models. The unified interface of PUMA is centered on an intermediate model called Core Scenario Model (CSM), which is extracted from the annotated design model. Experience shows that CSM is also necessary for cleaning and auditing the design information, and providing default interpretations in case it is incomplete, before creating a performance model.

The Carleton University responsiveness to suggestion scale: normative data and psychometric properties.

Abstract: A normative sample of 400 subjects was administered the Carleton University Responsiveness to Suggestion Scale (CURSS) in small groups. The Carleton scale yields three suggestibility scores for each subject; objective (CURSS:O) scores reflect overt response to suggestion, subjective (CURSS:S) scores reflect experiential response to suggestion, and objective-involuntariness (CURSS:OI) scores reflect the extent to which objectively “passed” responses were experienced as occurring involuntarily. Guttman scale analyses and factor analyses indicate that each dimension is primarily unidimensional and cumulative. CURSS:O scores had a bell-shaped distribution while CURSS:OI scores were much more strongly skewed toward the low suggestibility end of the distribution. Subjects who “passed” suggestions by objective criteria frequently rated their responses as primarily voluntary rather than involuntary. Implications of these findings for the measurement of hypnotic susceptibility are discussed.

Life in the slow lane: molecular mechanisms of estivation.

Abstract: Estivation is a state of aerobic hypometabolism used by organisms to endure seasonally arid conditions, often in desert environments. Estivating species are often active for only a few weeks each year to feed and breed and then retreat to estivate in sheltered sites, often underground. In general, estivation includes a strong reduction in metabolic rate, a primary reliance on lipid oxidation to fuel metabolism, and methods of water retention, both physical (e.g. cocoons) and metabolic (e.g. urea accumulation). The present review focuses on several aspects of metabolic adaptation during estivation including changes in the activities of enzymes of intermediary metabolism and antioxidant defenses, the effects of urea on estivator enzymes, enzyme regulation by reversible protein phosphorylation, protein kinases and phosphatases involved in signal transduction mechanisms, and the role of gene expression in estivation. The focus is on two species: the spadefoot toad, Scaphiopus couchii, from the Arizona desert; and the land snail, Otala lactea, a native of the Mediterranean region. The mechanisms of metabolic depression in estivators are similar to those seen in hibernation and anaerobiosis, and contribute to the development of a unified set of biochemical principles for the control of metabolic arrest in nature.