Showing papers by "Celal Bayar University published in 2000"

Anxiety, depression, and nature of acne vulgaris in adolescents.

Abstract: Background The reported prevalence of acne in adolescence is variable; improved treatment may have modified its prevalence and severity; acne has been related to psychiatric morbidity for many years. Methods Two thousand six hundred and fifty-seven high school students were examined, and adolescents with acne were interviewed about the subject of acne vulgaris. The severity of acne was graded using the Global Acne Grading System (GAGS). The Hospital Anxiety and Depression (HAD) scale was evaluated for one of every two subjects with acne (n = 308) and for the same number of sex-matched control subjects (n = 308) to determine the prevalence of depression and anxiety. Results Six hundred and fifteen of the subjects (23.1%) were determined to have acne. Acne prevalence in girls and boys was 16.1% and 29.2%, respectively (P < 0.001). Two hundred and twenty-five (15.8%) of 1424 boys and only 109 (8.8%) of 1233 girls had moderate or severe/very severe acne (P < 0.001), but the GAGS scores in the groups of boys and girls with acne were not significantly different. The acne and control groups showed no significant differences in the HAD anxiety and depression subscale scores. The HAD anxiety subscale scores of girls were significantly higher than those of boys in the acne group. The severity of acne was not correlated with the HAD anxiety or depression subscale scores. Conclusions Acne results in higher anxiety in adolescent girls. Although acne and moderate/severe acne are more common in adolescent boys, the severity of acne was found to be similar in boys and girls with acne. Adolescent girls are more vulnerable than boys to the negative psychological effects of acne.

A Geotraverse Across Northwestern Turkey: Tectonic Units of the Central Sakarya Region and their Tectonic Evolution

Abstract: Abstract In the Central Sakarya area of Turkey there are two main Alpine continental units, separated by a south verging ophiolitic complex which represents the root zone of the İzmir-Ankara Suture Belt. The Central Sakarya Terrane in the north includes two ‘Variscan’ tectonic units in its basement. The Söğüt Metamorphic rocks represent a Variscan ensimatic arc complex and the Tepeköy Metamorphic rocks are characteristically a forearc-trench complex. The unconformably overlying Triassic Soğukkuyu Metamorphic rocks correspond to a part of the Karakaya Formation and are interpreted as a Triassic rift basin assemblage. These units are unconformably overlain by a transgressive sequence of Liassic-Late Cretaceous age that represents the northeastward deepening carbonate platform of the Sakarya Composite Terrane. The middle tectonic unit (the Central Sakarya Ophiolitic Complex) comprises blocks and slices of dismembered ophiolites, blueschists and basic volcanic rocks with uppermost Jurassic-Lower Cretaceous radiolarite-limestone interlayers. Geochemical data from basalt blocks suggest mid-ocean ridge basalt (MORB)- and suprasubduction-type tectonic settings within the Neotethyan İzmir-Ankara Ocean. The southern tectonic unit includes basal polyphase metamorphosed clastic rocks (Sömdiken Metamorphics), intruded by felsic and basic dykes and overlain by thick-bedded marbles. This assemblage is unconformably overlain by continental clastic rocks gradually giving way to thick-bedded recrystallized limestones, cherty limestones and pelagic limestones intercalated with radiolarites, and finally by a thick high pressure-low temperature (HP-LT) metamorphic synorogenic flysch sequence. This succession is identical to the passive continental margin sequences of the Tauride Platform. It is suggested that this passive margin was subducted during the Late Cretaceous in an intraoceanic subduction zone and affected by HP-LT metamorphism. The emplacement of the allochthonous oceanic assemblages and the collision with the Central Sakarya Terrane was complete by the end of the Cretaceous.

Geochemical character and tectonic environment of Neotethyan ophiolitic fragments and metabasites in the Central Anatolian Crystalline Complex, Turkey

Abstract: Abstract The Central Anatolian Crystalline Complex (CACC) or Kırşehir Block is part of the metamorphosed leading edge of the Tauride-Anatolide Carbonate Platform. It contains oceanic remnants derived from the Neotethys Ocean (İzmir-Ankara-Erzincan branch) which separate it from the Sakarya microcontinent. Two tectonic units are distinguished: an amphibolite facies Mesozoic ‘basement’, dominated by platform marbles, over which is thrust a younger fragmented Upper Cretaceous ophiolite sequence. Three metabasite horizons were sampled to reconstruct the development of the oceanic components: (1) fragmented Upper Cretaceous (90-85 Ma) stratiform ophiolitic members comprising gabbros, sheeted dykes, basalt lavas and pelagic sediments thrust over all other units; (2) a tectonised admixture of basite, ultramafic and felsic blocks in an ophiolitic mélange (Upper Cretaceous matrix) thrust over the basement metamorphic rocks; and (3) amphibolites concordant with ‘basement’ marbles and minor pelagics of the largely (?)Triassic Kaleboynu Formation in the lower part of the carbonate platform. Metabasalts and metagabbros from isolated fragments of the stratiform ophiolites form geochemically coherent groups and indicate the influence of a subduction component during their development. It is considered that the suprasubduction zone ophiolites record the association of a tholeiitic arc and an adjacent back-arc basin with more mid-ocean ridge basalt (MORB)-like compositions. Metabasite blocks within the tectonised ophiolitic mélange slice are MORB like, together with minor ocean island basalt (OIB) and island arc basalts, and may be tectonically related to ophiolitic units within the accretionary wedge of the Ankara Mélange. Concordant amphibolites of the Kaleboynu Formation are largely OIB types and reflect an early ensialic rifting stage of the Tauride-Anatolide Carbonate Platform. Small ocean basins also developed at this time, as recorded by the presence of MORB and associated pelagics. The CACC block, together with parts of the Ankara Mélange, are considered to represent oceanic lithosphere (comprising both early spreading centre and latter subduction-influenced crust) and continental carbonate platform that were subsequently ejected from an accretionary-subduction complex on collision with the Sakarya microcontinent.

Patients with urinary incontinence often benefit from surgical detethering of tight filum terminale

Abstract: We retrospectively reviewed 77 patients with a tethered spinal cord syndrome to evaluate the results of neurosurgical treatment. The patients were divided into two groups: in group 1 there were 17 patients with primary tethered cord who had normal level conus medullaris (NLCM) and normal thickness filum terminale (NTFT) with urinary incontinence, and group 2 was made up of 60 patients with secondary spinal cord tethering after a previous closure of a midline fusion defect who had a low-lying conus medullaris. Neurological examination, radiography, urodynamic tests and electrophysiological findings confirmed the diagnosis. Conventionally, tethered cord syndrome has been defined as a state in which the conus medullaris is located below the L1-2 disc space. However, in a patient with urinary incontinence and a hyperreflexive type of neurogenic bladder, in whom the conus medullaris is found to be at the normal level, there may still be cord tethering that is causing the incontinence. In this study the comparison was based on evaluation of the response to treatment and general characteristics of the syndrome in both groups of patients to draw attention to the general approach to this incapacitating mal-development.

Formation and emplacement ages of the SSZ‐type Neotethyan ophiolites in Central Anatolia, Turkey: palaeotectonic implications

Abstract: Isolated outcrops of ophiolitic rocks, termed the Central Anatolian Ophiolites, are found as allochthonous bodies in the Central Anatolian Crystalline Complex, that represent the metamorphosed passive northern edge of the Tauride–Anatolide Platform, central Turkey. In terms of pseudostratigraphic relationships of the magmatic units and their chemical designation, the Central Anatolian Ophiolites exhibit a supra-subduction zone (fore-arc) setting within the Vardar–Izmir–Ankara–Erzincan segment of the Neotethys. The epi-ophiolitic sedimentary cover of the Central Anatolian Ophiolites is generally characterized by epiclastic volcanogenic deep-sea sediments and debris flows intercalated with pelagic units. The richest and most significant planktonic foraminiferal association recorded from the lowest pelagic members infer a formation age of early–middle Turonian to early Santonian. K/Ar ages of post-collisional granitoids (81–65 Ma) intruding the basement rocks as well as the Central Anatolian Ophiolites suggest a post-early Santonian to pre-middle Campanian emplacement age. The marked high volume of epiclastic volcanogenic sediments intercalated with the pelagics of the Central Anatolian Ophiolite is suggestive of rifting in a marginal sea adjacent to a volcanic arc. Penecontemporaneous tectonism is reflected in repetitions in the stratigraphy and in debris flows, which result from major slides and mass-gravity reworking of pre-existing units and of arc-derived volcanics and sediments. Correlating the rock units and formation/obduction ages of the Central Anatolian Ophiolites with further supra-subduction zone type ophiolites in the eastern (Turkey) and western (Greece) parts of the Vardar–Izmir–Ankara–Erzincan segment of Neotethys we conclude that the intraoceanic subduction in the east is definitely younger and the closure history of this segment is more complex than previously suggested. Copyright © 2000 John Wiley & Sons, Ltd.

The effect of propolis extract in experimental chemical corneal injury.

Abstract: Purpose: To investigate the effect of propolis, a natural resin produced by honeybees, in the treatment of alkali-injured rabbit eyes. Method: A corneal alkali burn was induced by applying filter paper immersed in 1 N NaOH on the central axis of the right corneas of 24 rabbits for 30 s. The animals were divided into three treatment groups: group 1 (control) was given 0.3% tobramycin and phosphate-buffered solution; group 2 was treated with antibiotic coverage and topical 1% ethanolic extract of propolis; group 3 received antibiotic coverage and topical 1% dexamethasone. The dexamethasone-treated group was maintained as the positive control. Drugs were instilled 4 times a day for 7 days. The corneal inflammation was evaluated by calculating the average inflammatory index obtained from clinical observation of the ciliary hyperemia, central and peripheral corneal edema at 24 h, 48 h, on day 5 and day 7, before sacrificing the animals. Then, the corneas underwent routine histological examination. Results: The effects of dexamethasone and propolis on healing of injured corneas were similar (p > 0.05) and significantly better than controls at 24 h (p 0.05). Conclusions: Our study shows that propolis has an anti-inflammatory effect comparable to dexamethasone in chemical corneal injury.

Relation of optic disc topography and age to thickness of retinal nerve fibre layer as measured using scanning laser polarimetry, in normal subjects.

Abstract: Aims—To evaluate the relation of the optic nerve head topographic measurements and age with the thickness of the retinal nerve fibre layer (RNFL) in normal Caucasoid subjects by means of scanning laser polarimetry and tomography. Methods—Topographic optic disc measurements and RNFL thickness values of 38 normal Caucasoid subjects of both sexes aged 20 to 78 were measured using a confocal scanning laser ophthalmoscope and a confocal scanning laser polarimeter. One eye was randomly selected for statistical analysis.The eVects of optic disc size, age, and optic disc head topographic measurements of total and regional RNFL thickness were evaluated. Results—Age showed a significant correlation with the integral of the total RNFL thickness (R=˛0.341, p 0.05). Conclusion—The thickness of total as well as superior and inferior quadrant peripapillary RNFL as measured by scanning laser polarimetry increased significantly with an increase in optic disc size. The cross sectional area occupied by superior and inferior polar RNFL increased significantly with an increase in NRA. The total cross sectional area occupied by RNFL decreased significantly with an increase in age. The eVects of optic disc size, age, and NRA should be considered when the peripapillary RNFL thickness is evaluated. (Br J Ophthalmol 2000;84:473‐478)

Radioluminescence and thermoluminescence of rare earth element and phosphorus-doped zircon

Abstract: The radioluminescence and thermoluminescence spectra of synthetic zircon crystals doped with individual trivalent rare earth element (REE) ions (Pr, Sm, Eu, Gd, Dy, Ho Er, and Yb) and P are reported in the temperature range 25 to 673 K. Although there is some intrinsic UV/blue emission from the host lattice, the dominant signals are from the rare-earth sites, with signals characteristic of the REE3+ states. The shapes of the glow curves are different for each dopant, and there are distinct differences between glow peak temperatures for different rare-earth lines of the same element. Within the overall set of signals there are indications of linear trends in which some glow peak temperatures vary as a function of the ionic size of the rare earth ions. The temperature shifts of the peaks are considerable, up to 200°, and much larger than those cited in other rare-earth-doped crystals of LaF3 and Bi4Ge3O12. The data clearly suggest that the rare-earth ions are active both in the trapping and luminescence steps, and hence the TL occurs within localized defect complexes that include REE3+ ions.

Immediate hair transplantation into a newly closed wound to conceal the final scar on the hair-bearing skin.

Abstract: A surgical incision after suturing usually leaves a visible scar on the hair-bearing skin, even after optimal wound conditions. The conspicuousness of such a scar results from its linear continuity and hairlessness. To prevent this effect, a row of micrografts or minigrafts was inserted between the wound edges immediately after wound closure. The hair grafts that were transplanted were dissected from the discharged skin in the same surgical procedure, if feasible. Otherwise, a mini donor strip was harvested from the mastoid scalp to dissect the hair grafts. The final linear scar was interrupted and concealed sufficiently with the growth of the transplanted hairs. Tension-free closure is required to obtain a satisfactory result with this technique.

Religious fasting and intraocular pressure.

Abstract: PURPOSE: To determine the effects of Islamic religious fasting on intraocular pressure. METHODS: The authors measured diurnal intraocular pressure values during religious fasting and 1 month later in 38 healthy male volunteers with a mean age of 22.4 +/- 2.7 years. Body weight and urine specific gravity were determined to assess the extent of dehydration caused by fasting. RESULTS: Although each patient had weight loss (0.1-1.4 kg) representing a slight dehydration caused by fasting, intraocular pressure values were not statistically different between fasting and nonfasting periods (P > 0.05). CONCLUSION: Fasting did not alter diurnal intraocular pressure values in healthy people.

Reanimation of early facial paralysis with hypoglossal/facial end-to-side neurorrhaphy: a new approach.

Abstract: The classic hypoglossal transfer to the facial nerve invariably results in profound functional deficits in speech, mastication, and swallowing, and causes synkinesis and involuntary movements in the facial muscles despite good reanimation. Techniques such as a hypoglossal/facial nerve interpositional jump graft and splitting the hypoglossal nerve cause poor functional results in facial reanimation and mild-to-moderate hemiglossal atrophy, respectively. Direct hypoglossal/facial nerve cross-over through end-to-side coaptation without tension was done in three fresh cadavers and four patients. The patients had facial paralysis for less than 7 months. Complete mobilization of the facial nerve trunk and its main branches beyond the pes anserinus from the stylomastoid foramen, division of the frontal branch, if necessary, and superior elevation of the hypoglossal nerve after dividing the descendens hypoglossi, thyrohyoidal branches, occipital artery, and retromandibular veins were performed. The end of the facial nerve was hooked up through both a quarter of a partial oblique neurotomy and a perineurial window at the side of the hypoglossal nerve. Temporalis muscle transfer to the eyelids and the first stage of cross-facial nerve transfer were performed simultaneously. None of the patients experienced hemiglossal atrophy, synkinesis, and involuntary movements of the facial muscles. Regarding facial reanimation, one patient had excellent, one patient good, and the others fair and poor results after a follow-up of at least 1 year.

Changes in the plasma activities of protein C and protein S during pregnancy.

Abstract: The objective of the study was to determine the changes in the plasma activities of protein C and protein S that occur during normal pregnancy In this prospective cross-sectional study, plasma activities of protein C and protein S were measured in 32 normal pregnant women in the first, second and third trimester and 6 weeks after delivery There was a significant fall in protein C and protein S activities during normal pregnancy compared with the post-puerperal period. The activities of protein C and protein S also gradually decreased throughout pregnancy (p < 0.01). Increasing plasma volume during normal pregnancy and its dilutional effect might play some role in the low activities of protein S observed. The normal falls in protein S and protein C activities make it difficult to diagnose protein S and C deficiency during pregnancy. Based on our findings, if a woman has a thromboembolic event during pregnancy, testing for a definitive diagnosis of protein C or protein S deficiency or functional failure should be delayed until at least 6 weeks postpartum.

Ocular findings in a measles epidemic among young adults.

Abstract: PURPOSE: To present ocular findings in a measles epidemic outbreak among young adults. METHODS: Ophthalmic lesions in an unselected group of 61 young military personnel with measles were followed. Eighteen of the patients had symmetric keratitis in both eyes. They were treated with diclofenac sodium eyedrops qid in the right eye, while the left eye was observed untreated. The disappearance of the corneal lesions in both eyes was compared. RESULTS: Forty patients (65.6%) had measles conjunctivitis with bulbar and tarsal conjunctival hyperemia. Five (8.2%) had increased mucous secretion. Thirty-five (57.4%) had superficial punctate corneal epithelial and subepithelial lesions which stained with fluorescein. Ten patients had corneal lesions without evident conjunctival pathology. Fourteen patients had subconjunctival hemorrhages, 12 of whom had bilateral lesions mostly in the superonasal quadrant. The time to disappearance of corneal lesions was 4.5±3.2 days in the diclophenac-treated right eyes, and 4.1±3.8...

Total tongue reconstruction with free functional gracilis muscle transplantation: a technical note and review of the literature.

Abstract: The tongue is one of the most difficult structures of the body to reconstruct if more than 85% to 90% of it has been resected. A functional neotongue requires both soft-tissue bulk and restoration of muscle function. The innervated gracilis muscle flap folded on itself was used to reconstruct a total glossectomy defect. The genioglossus muscle, which makes the greatest contribution to swallowing, and the mylohyoid muscle, which elevates the larynx to prevent aspiration, were simulated with the design and placement of the gracilis muscle. The muscle was placed and secured longitudinally from the remnant of the tongue base and pharynx to the mandible, and then folded on itself and attached to the hyoid bone. The obturator nerve to the gracilis was coapted with the hypoglossal nerve. The patient was able to resume oral feeding without aspiration. Electromyographic results demonstrated reinnervation of the flap with active elevation of the mouth base. The patient died 1 year postoperatively because of recurrence of her disease. This type of design and placement of gracilis muscle transplantation is recommended.

Sonographic measurement of the thymus in newborns: close association between thymus size and birth weight

Abstract: Sir: In infants, the thymus gland varies greatly in both size and shape; therefore X-ray diagnosis of absence or enlargement of the thymus is uncertain and unreliable [4]. In this study, the volume of thymus was measured in 65 full-term newborns by ultrasound. Newborns with a sign, symptom and/or laboratory ®nding of congenital abnormality, birth trauma, neonatal infection or metabolic disorders were excluded. The ultrasound examination was performed with a TOSBEE Sonolayer a Ultrasound Diagnostic Scanner (Toshiba Corporation Medical System Division, Tokyo, Japan) type SSA 240 A 7.5 MHz linear probe. Thymic measurements were made according to the ultrasound method described by Hesselbach et al. [3]. Pearson correlation coecients and Student's t-test were used for statistical analysis, using the thymic index i.e. the largest transverse diameter (cm) ́ largest sagittal area (cm). Table 1 shows minimum, maximum and mean values and the percentage distribution of birth weight, birth length and thymic measurements in 65 newborns (37 males and 28 females). The thymic index was normally distributed. The largest transverse diameter of the thymus in males was signi®cantly higher than that of females (3.32 ‹ 0.63 versus 2.95 ‹ 0.7, P ˆ 0.027). There was no signi®cant di€erence between male and female newborns in terms of the largest sagittal area and the thymic index (4.25 ‹ 1.34 versus 3.91 ‹ 1.41, P ˆ 0.321, and 14.7 ‹ 6.3 versus 12.1 ‹ 6, P ˆ 0.104, respectively). Four out of six newborns with a thymic index greater than 22.4 (90th percentile of the thymic index value) were male, whereas only two out of six newborns with a thymic index of less than 4.6 (10th percentile of the thymic index value) were male. A statistically signi®cant correlation was found between largest transverse diameter and birth weight; largest sagittal area and birth weight; thymic index and birth weight (r ˆ 0.276, P ˆ 0.026; r ˆ 0.373, P ˆ 0.002; and r ˆ 0.375, P ˆ 0.002, respectively). In addition, a signi®cant correlation between the largest transverse diameter and birth length and between thymic index and birth length were also found (r ˆ 0.345, P ˆ 0.005 and r ˆ 0.262, P ˆ 0.035, respectively). Sonographic measurement of the volume of the thymus is an alternative to radiographic determination, the latter using an uncertain and unreliable method for assessing the thymus size in infants. In post-mortem examinations after perinatal deaths, thymus weight has been found to be signi®cantly correlated with birth weight [1]. Con®rming this ®nding, we found that the ultrasound-estimated volume of the organ (``thymic index'') in newborns is signi®cantly correlated with birth weight. Furthermore, it is known that the thymus is larger in males than in females during the ®rst 2 years of life [4]. But no statistically signi®cant di€erence in terms of thymus size was found between male and female newborns except in the largest transverse diameter of the organ in this study. However, most of the cases with a large thymus were male, whereas most of the cases with a small thymus were female. In conclusion, we suggest that ultrasound examination of the thymus in newborns may be used for assessment of thymus size in various congenital diseases a€ecting the thymus, such as Di George syndrome, distal trisomy 14q syndrome, pediatric human immunode®ciency virus infection, ectodermal dysplasia and severe combined immunode®ciency [2, 5].