Celal Bayar University

About: Celal Bayar University is a education organization based out in Magnesia ad Sipylum, Turkey. It is known for research contribution in the topics: Population & Heat transfer. The organization has 2960 authors who have published 6024 publications receiving 100646 citations.

The prevalence of hyperprolactinaemia in overt and subclinical hypothyroidism.

Abstract: The aims of this study were to: 1) determine the prevalence of hyperprolactinaemia in patients with newly diagnosed subclinical and overt hypothyroidism, and 2) investigate the change in PRL levels with treatment. In this observational study, patients with a new diagnosis of hypothyroidism in our endocrinology clinic were approached for participation, as were healthy controls. Patients with medical reasons for having elevated PRL levels, lactating and pregnant women were excluded from the study. No patient had kidney or liver disease. After examination to determine if clinical causes of PRL elevation were present, serum levels of thyrotropin (TSH), free thyroxine, free triiodothyronine and PRL were measured and correlation of PRL levels with the severity of hypothyroidism (overt or subclinical) was performed. Fifty-three patients (45 women, 8 men, mean age 45.3±12.2 years) had overt hypothyroidism. One hundred forty-seven patients (131 women, 16 men, mean age 42.9±12.6 years) had subclinical hypothyroidism. One hundred healthy persons (85 women, 15 men, mean age 43.9±11.4 years) participated as controls. The same blood tests were repeated in patients after normalization of TSH levels with L-thyroxine treatment. PRL elevation was found in 36% of patients with overt hypothyroidism, and in 22% of patients with subclinical hypothyroidism. PRL levels decreased to normal in all patients after thyroid functions normalized with L-thyroxine treatment. In the hypothyroid patients (overt and subclinical) a positive correlation was found between TSH and PRL levels (r=0.208, p=0.003). PRL regulation is altered in overt and subclinical hypothyroidism, and PRL levels normalize with appropriate L-thyroxine treatment.

First Observation of a Baryonic B-c(+) Decay

Abstract: A baryonic decay of the B-c(+) meson, B-c(+) -> J/psi p (p) over bar pi(+) is observed for the first time, with a significance of 7.3 standard deviations, in pp collision data collected with the LHCb detector and corresponding to an integrated luminosity of 3.0 fb(-1) taken at center-of-mass energies of 7 and 8 TeV. With the B-c(+) -> J/psi pi(+) decay as the normalization channel, the ratio of branching fractions is measured to be B(B-c(+) -> J/psi p (p) over bar pi(+)) /B(B-c(+) -> J/psi pi(+)) = 0.143(-0.034)(+0.039) (stat) +/- 0.013 (syst). The mass of the B-c(+) messon is determined as M(B-c(+)) = 6274.0 +/- 0.4 (sysst) MeV/c(2), using the B-c(+) -> J/psi p (p) over bar pi(+) channel.

Characterization and immobilization of Trametes versicolor laccase on magnetic chitosan-clay composite beads for phenol removal.

Abstract: Laccase from Trametes versicolor was immobilized on magnetic chitosan–clay composite beads by glutaraldehyde crosslinking. The physical, chemical, and biochemical properties of the immobilized laccase and its application in phenol removal were comprehensively investigated. The structure and morphology of the composite beads were characterized by SEM, TGA, and FTIR analyses. The immobilized laccase showed better storage stability and higher tolerance to the changes in pH and temperature compared with free laccase. Moreover, the immobilized laccase retained more than 75% of its original activity after 10 cycles. The efficiency of phenol removal by immobilized laccase was about 80% under the optimum conditions after 4 h.