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Institution

Centers for Disease Control and Prevention

GovernmentAtlanta, Georgia, United States
About: Centers for Disease Control and Prevention is a government organization based out in Atlanta, Georgia, United States. It is known for research contribution in the topics: Population & Public health. The organization has 58238 authors who have published 82592 publications receiving 4405701 citations. The organization is also known as: CDC & Centers for Disease Control and Prevention (CDC).


Papers
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Journal ArticleDOI
09 Oct 2008-Nature
TL;DR: The synteny and isochore structure of P. vivax chromosomes are described, and it is shown that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously.
Abstract: The human malaria parasite Plasmodium vivax is responsible for 25-40% of the approximately 515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms and often causes relapses months after a primary infection has cleared. Despite its importance as a major human pathogen, P. vivax is little studied because it cannot be propagated continuously in the laboratory except in non-human primates. We sequenced the genome of P. vivax to shed light on its distinctive biological features, and as a means to drive development of new drugs and vaccines. Here we describe the synteny and isochore structure of P. vivax chromosomes, and show that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously. Completion of the P. vivax genome provides the scientific community with a valuable resource that can be used to advance investigation into this neglected species.

787 citations

Journal ArticleDOI
TL;DR: A consensus recommendation for the amount of sleep needed to promote optimal health in adults, using a modified RAND Appropriateness Method process, is summarized here.
Abstract: Sleep is essential for optimal health. The American Academy of Sleep Medicine (AASM) and Sleep Research Society (SRS) developed a consensus recommendation for the amount of sleep needed to promote optimal health in adults, using a modified RAND Appropriateness Method process. The recommendation is summarized here. A manuscript detailing the conference proceedings and evidence supporting the final recommendation statement will be published in SLEEP and the Journal of Clinical Sleep Medicine.

786 citations

Journal ArticleDOI
TL;DR: A prospective, laboratory-based surveillance project obtained accurate data on meningitis in a population of 34 million people during 1986, suggesting that improvements in early detection and antibiotic treatment may have occurred since that time.
Abstract: A prospective, laboratory-based surveillance project obtained accurate data on meningitis in a population of 34 million people during 1986. Haemophilus influenzae was the most common cause of bacterial meningitis (45%), followed by Streptococcus pneumoniae (18%), and Neisseria meningitidis (14%). Rates of H. influenzae meningitis varied significantly by region, from 1.9/100,000 in New Jersey to 4.0/100,000 in Washington state. The overall case fatality rates for meningitis were lower than those reported in several studies from the early 1970s, suggesting that improvements in early detection and antibiotic treatment may have occurred since that time. Concurrent surveillance was also performed for all invasive disease due to the five most common causes of bacterial meningitis. Serotypes of group B streptococcus other than type III caused more than half of neonatal group B streptococcal disease and mortality, suggesting that an optimal vaccine preparation must be multivalent. Of the organisms evaluated, group B streptococcus was the second most common cause of invasive disease in persons greater than 5 years old.

785 citations

Journal ArticleDOI
TL;DR: Cross species poultry-to-person transmission of this new reassortant H7N9 virus is associated with severe pneumonia and multiorgan dysfunction in human beings and monitoring of the viral evolution and further study of disease pathogenesis will improve disease management, epidemic control, and pandemic preparedness.

784 citations

Journal ArticleDOI
TL;DR: Findings were similar to those from previous years in which rates of TBI were highest for young children (aged 0–4) and men, and the leading causes were falls and motor vehicle traffic.
Abstract: Traumatic brain injury (TBI) is an important public health problem in the United States. In 2003, there were an estimated 1,565,000 TBIs in the United States: 1,224,000 emergency department visits, 290,000 hospitalizations, and 51,000 deaths. Findings were similar to those from previous years in which rates of TBI were highest for young children (aged 0-4) and men, and the leading causes of TBI were falls and motor vehicle traffic.

783 citations


Authors

Showing all 58382 results

NameH-indexPapersCitations
Graham A. Colditz2611542256034
David J. Hunter2131836207050
Bernard Rosner1901162147661
Richard Peto183683231434
Aaron R. Folsom1811118134044
Didier Raoult1733267153016
James F. Sallis169825144836
David R. Jacobs1651262113892
Steven N. Blair165879132929
Gordon J. Freeman164579105193
Dennis R. Burton16468390959
Rory Collins162489193407
Ali H. Mokdad156634160599
Caroline S. Fox155599138951
Paul Elliott153773103839
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202327
2022254
20215,505
20205,426
20194,527
20184,344