Institution
Central Drug Research Institute
Facility•Lucknow, Uttar Pradesh, India•
About: Central Drug Research Institute is a facility organization based out in Lucknow, Uttar Pradesh, India. It is known for research contribution in the topics: Leishmania donovani & Brugia malayi. The organization has 4357 authors who have published 7257 publications receiving 143871 citations. The organization is also known as: Central Drug Research Institute, Lucknow & CDRI.
Papers published on a yearly basis
Papers
More filters
TL;DR: The in vitro susceptibility profile to amikacin, linezolid, clarithromycin, imipenem, cefoxitin, clofazimine and tigecycline was established for 67 strains belonging to the Mycobacterium abscessus complex.
50 citations
TL;DR: A series of 3,5-disubstituted thiadiazine thiones synthesized by reaction of primary amines with carbon disulphide followed by cyclocondensation of the resulting intermediate with formaldehyde and primary amine or amino acids showed antimycobacterial activity in vitro and exhibited activity in vivo.
50 citations
United Nations Economic Commission for Africa1, World Health Organization2, University of Antwerp3, University of London4, Theodor Bilharz Research Institute5, University of Buea6, Central Drug Research Institute7, Chimie ParisTech8, The Hertz Corporation9, University of Washington10, McGill University11
TL;DR: This work suggests that the efficiency of early drug discovery for neglected diseases can be enhanced through a collaborative, multi-pathogen approach.
Abstract: New chemical entities are desperately needed that overcome the limitations of existing drugs for neglected diseases. Screening a diverse library of 10,000 drug-like compounds against 7 neglected disease pathogens resulted in an integrated dataset of 744 hits. We discuss the prioritization of these hits for each pathogen and the strong correlation observed between compounds active against more than two pathogens and mammalian cell toxicity. Our work suggests that the efficiency of early drug discovery for neglected diseases can be enhanced through a collaborative, multi-pathogen approach.
50 citations
TL;DR: The studies provide evidence that 4-SO(4)GalNAc possesses a promising feature for targeting resident macrophages and its application in the conditions of leishmaniasis is in the offing.
50 citations
TL;DR: Various secondary and tertiary alcohols including benzylic systems were found to be equally reactive with moderate to excellent yields obtained in all cases.
50 citations
Authors
Showing all 4385 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Sanjay Kumar | 120 | 2052 | 82620 |
| John A. Katzenellenbogen | 95 | 691 | 36132 |
| Brajesh K. Singh | 83 | 401 | 24101 |
| Gaurav Sharma | 82 | 1244 | 31482 |
| Sudhir Kumar | 82 | 524 | 216349 |
| Pramod K. Srivastava | 79 | 390 | 27330 |
| Mohan K. Raizada | 75 | 473 | 21452 |
| Syed F. Ali | 71 | 446 | 18669 |
| Ravi Shankar | 66 | 672 | 19326 |
| Ramesh Chandra | 66 | 620 | 16293 |
| Manoj Kumar | 65 | 408 | 16838 |
| Manish Kumar | 61 | 1425 | 21762 |
| Anil Kumar Saxena | 58 | 310 | 10107 |
| Sanjay Krishna | 56 | 624 | 13731 |
| Naibedya Chattopadhyay | 56 | 242 | 9795 |