Institution
Central Drug Research Institute
Facility•Lucknow, Uttar Pradesh, India•
About: Central Drug Research Institute is a facility organization based out in Lucknow, Uttar Pradesh, India. It is known for research contribution in the topics: Catalysis & Leishmania donovani. The organization has 4357 authors who have published 7257 publications receiving 143871 citations. The organization is also known as: Central Drug Research Institute, Lucknow & CDRI.
Topics: Catalysis, Leishmania donovani, Ring (chemistry), Aryl, Apoptosis
Papers published on a yearly basis
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TL;DR: The results suggest that AT1 receptors play a facilitatory role in STZ induced memory deficit and corroborate number of human studies that At1 receptor blockers can be used therapeutically against cognitive decline in hypertensive patients.
86 citations
TL;DR: The results propose anticancer efficacy of PLA-Qt nanoparticles in terms of its sustained release kinetics revealing novel vehicle for the treatment of cancer.
85 citations
TL;DR: It is concluded from the results obtained that amentoflavone produces its antidepressant effect through interaction with 5-HT2 receptor and α1-, and α2-adrenoceptors while the anxiolytic effect involved the ionotropic GABA receptor.
Abstract: The root decoction of Cnestis ferruginea (CF) Vahl DC (Connaraceae) is used in traditional African medicine in the management of psychiatric disorders. This study presents the antidepressant and anxiolytic effects of amentoflavone (CF-2) isolated from the root extract of C. ferruginea . The antidepressant effect was studied using the forced swimming (FST) and tail suspension tests (TST) while the hole-board, elevated plus maze (EPM) and light/dark tests were used to evaluate the anxiolytic effect. Acute treatment with CF extract and amentoflavone significantly (p The pretreatment of mice with metergoline (4 mg/kg, i.p., a 5-HT2 receptor antagonist), prazosin (62.5 μg/kg, i.p., an α1-adrenoceptor antagonist), and yohimbine (1 mg/kg, i.p., an α2-adrenoceptor antagonist), but not sulpiride (50 mg/kg, i.p., a dopamine D2 receptor antagonist), cyproheptadine (3 mg/kg, i.p., a 5-HT2 receptor antagonist), atropine (1 mg/kg, i.p., a muscarinic receptor antagonist) 15 mins before the administration of amentoflavone (50 mg/kg; p.o.) significantly prevented its antiimmobility effect in the FST. CF extract and CF-2 significantly (p
85 citations
TL;DR: An efficient and green method has been developed for the synthesis of tryptanthrin employing β-cyclodextrin as a catalyst in aqueous media at room temperature from isatoic anhydride and isatin.
85 citations
TL;DR: The identification of a protein (Tma12) from an edible fern, Tectaria macrodonta (Fee) C. Chr.
Abstract: Cotton plants are protected from the sap-sucking whitefly and a viral disease it transmits by transgenic expression of an insecticidal fern protein.
85 citations
Authors
Showing all 4385 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Sanjay Kumar | 120 | 2052 | 82620 |
| John A. Katzenellenbogen | 95 | 691 | 36132 |
| Brajesh K. Singh | 83 | 401 | 24101 |
| Gaurav Sharma | 82 | 1244 | 31482 |
| Sudhir Kumar | 82 | 524 | 216349 |
| Pramod K. Srivastava | 79 | 390 | 27330 |
| Mohan K. Raizada | 75 | 473 | 21452 |
| Syed F. Ali | 71 | 446 | 18669 |
| Ravi Shankar | 66 | 672 | 19326 |
| Ramesh Chandra | 66 | 620 | 16293 |
| Manoj Kumar | 65 | 408 | 16838 |
| Manish Kumar | 61 | 1425 | 21762 |
| Anil Kumar Saxena | 58 | 310 | 10107 |
| Sanjay Krishna | 56 | 624 | 13731 |
| Naibedya Chattopadhyay | 56 | 242 | 9795 |