Institution
Central European Institute of Technology
Nonprofit•Brno, Czechia•
About: Central European Institute of Technology is a nonprofit organization based out in Brno, Czechia. It is known for research contribution in the topics: Gene & Chronic lymphocytic leukemia. The organization has 2137 authors who have published 4225 publications receiving 77973 citations. The organization is also known as: CEITEC.
Topics: Gene, Chronic lymphocytic leukemia, Population, Genome, Arabidopsis
Papers published on a yearly basis
Papers
More filters
TL;DR: This document describes the development and use of MiXCR, a software for comprehensive adaptive immunity profiling, and some of the techniques used in its development.
Abstract: MiXCR: software for comprehensive adaptive immunity profiling. MiXCR: software for comprehensive adaptive immunity profiling. MiXCR: software for comprehensive adaptive immunity profiling. MiXCR: software for comprehensive adaptive immunity profiling.MiXCR: software for comprehensive adaptive immunity profiling.
1,137 citations
Paris 12 Val de Marne University1, University Medical Center Groningen2, Eindhoven University of Technology3, University Hospital of Lausanne4, French Institute of Health and Medical Research5, Università Campus Bio-Medico6, University of Belgrade7, University of Cologne8, Ludwig Maximilian University of Munich9, École Polytechnique Fédérale de Lausanne10, Turku University Hospital11, University of Regensburg12, Università telematica San Raffaele13, Paris Descartes University14, Paracelsus Private Medical University of Salzburg15, University of Bern16, Universidade Nova de Lisboa17, Medical Park18, University of Göttingen19, University of Messina20, Central European Institute of Technology21, University of Siena22, University of Turku23, University of Tübingen24
TL;DR: These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018, and are based on the differences reached in therapeutic efficacy of real vs. sham rT MS protocols.
822 citations
TL;DR: PDBsum is a web server providing structural information on the entries in the Protein Data Bank, primarily image‐based and include protein secondary structure, protein‐ligand and protein‐DNA interactions, PROCHECK analyses of structural quality, and many others.
Abstract: PDBsum is a web server providing structural information on the entries in the Protein Data Bank (PDB). The analyses are primarily image-based and include protein secondary structure, protein-ligand and protein-DNA interactions, PROCHECK analyses of structural quality, and many others. The 3D structures can be viewed interactively in RasMol, PyMOL, and a JavaScript viewer called 3Dmol.js. Users can upload their own PDB files and obtain a set of password-protected PDBsum analyses for each. The server is freely accessible to all at: http://www.ebi.ac.uk/pdbsum.
740 citations
University of Cologne1, Hacettepe University2, Boston Children's Hospital3, Katholieke Universiteit Leuven4, Post Graduate Institute of Medical Education and Research5, Pasteur Institute6, Necker-Enfants Malades Hospital7, Catholic University of the Sacred Heart8, National and Kapodistrian University of Athens9, Statens Serum Institut10, University Medical Center Utrecht11, Second Military Medical University12, University of Delhi13, Carlos III Health Institute14, Central European Institute of Technology15, Hospital General Universitario Gregorio Marañón16, University of Liverpool17, Innsbruck Medical University18, Radboud University Nijmegen Medical Centre19, Manchester Academic Health Science Centre20, University of Milan21, University of Würzburg22
TL;DR: These European Society for Clinical Microbiology and Infectious Diseases and European Confederation of Medical Mycology Joint Clinical Guidelines focus on the diagnosis and management of mucormycosis and strongly recommend continuing treatment until complete response demonstrated on imaging and permanent reversal of predisposing factors.
725 citations
TL;DR: In this review, attention is paid to metallothioneins as small, cysteine-rich and heavy metal-binding proteins, which participate in an array of protective stress responses, which plays a key role in regulation of zinc levels and distribution in the intracellular space.
Abstract: Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause the molecule to become highly reactive. The free radicals are also known to play a dual role in biological systems, as they can be either beneficial or harmful for living systems. It is clear that there are numerous mechanisms participating on the protection of a cell against free radicals. In this review, our attention is paid to metallothioneins (MTs) as small, cysteine-rich and heavy metal-binding proteins, which participate in an array of protective stress responses. The mechanism of the reaction of metallothioneins with oxidants and electrophilic compounds is discussed. Numerous reports indicate that MT protects cells from exposure to oxidants and electrophiles, which react readily with sulfhydryl groups. Moreover, MT plays a key role in regulation of zinc levels and distribution in the intracellular space. The connections between zinc, MT and cancer are highlighted.
640 citations
Authors
Showing all 2149 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Jiří Friml | 95 | 290 | 37954 |
| Martin Pumera | 87 | 768 | 37404 |
| Jiří Šponer | 73 | 329 | 19600 |
| Frank Van Breusegem | 70 | 190 | 24885 |
| Jan Novak | 70 | 320 | 16150 |
| Michal Otyepka | 66 | 345 | 17943 |
| Ingo Schubert | 65 | 248 | 13557 |
| René Kizek | 61 | 672 | 16554 |
| Riet De Rycke | 60 | 161 | 10688 |
| Vojtech Adam | 55 | 611 | 14442 |
| Jan M. Macak | 55 | 189 | 13559 |
| Eva Benková | 54 | 107 | 18212 |
| Dmitriy M. Chudakov | 51 | 110 | 11968 |
| František Foret | 50 | 212 | 8617 |
| Martin A. Lysak | 49 | 138 | 9571 |