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Institution

Chandka Medical College

EducationLarkana, Pakistan
About: Chandka Medical College is a(n) education organization based out in Larkana, Pakistan. It is known for research contribution in the topic(s): Population & Outpatient clinic. The organization has 106 authors who have published 108 publication(s) receiving 1170 citation(s).


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Journal ArticleDOI
TL;DR: The study shows that analyzing levels of Al, Cd, and Pb may be useful in hemodialysis patients in evaluating TEs status, and this work determines total content of toxic elements—aluminum (Al), cadmium (Cd), and lead (Pb)—in whole blood and urine samples of male chronic renal failure patients on maintenance heModialysis from 2006 to 2007.
Abstract: The determination of toxic elements in the biological samples of human beings is an important clinical screening procedure. The aim of this work was to determine total content of toxic elements—alu...

116 citations

Journal ArticleDOI
TL;DR: Knowledge about mode of transmission of blood borne pathogens is very low and use of universal precautions can improve with increase in knowledge, but this cannot be said to be a cause for concern.
Abstract: We conducted an assessment of knowledge about blood borne pathogens (BBP) and use of universal precautions at first level care facilities (FLCF) in two districts of Pakistan. We conducted a cross-sectional survey and selected three different types of FLCFs ; public, general practitioners and unqualified practitioners through stratified random sampling technique. At each facility, we interviewed a prescriber, a dispenser, and a housekeeper for knowledge of BBPs transmission and preventive practices, risk perception, and use of universal precautions. We performed multiple linear regression to assess the effect of knowledge score (11 items) on the practice of universal precautions score (4 items- use of gloves, gown, needle recapping, and HBV vaccination). We interviewed 239 subjects. Most of the participants 128 (53%) were recruited from general practitioners clinics and 166 (69.5%) of them were dispensers. Mean (SD) knowledge score was 3.8 (2.3) with median of 4. MBBS prescribers had the highest knowledge score while the housekeepers had the lowest. Mean universal precautions use score was 2.7 ± 2.1. Knowledge about mode of transmission and the work experience alone, significantly predicted universal precaution use in multiple linear regression model (adR2 = 0.093). Knowledge about mode of transmission of blood borne pathogens is very low. Use of universal precautions can improve with increase in knowledge.

85 citations

Journal ArticleDOI
TL;DR: Some new endemic areas of Cutaneous leishmaniasis in Pakistan are reported, and an outbreak of the disease was observed in the region recently.
Abstract: Background Cutaneous leishmaniasis (CL) is endemic in Pakistan and is widely spreading. Recently, an outbreak of the disease was observed in the region. We report some new endemic areas of CL in the country. Methods A total of 1210 cases of CL who visited our department from 1996 to 2001 are reported. Among them, 760 were residents of the Jacobabad, Larkana, and Dadu districts of Sindh province and had never previously traveled to endemic areas. These districts have never been reported/recognized as endemic for CL. Others were residents of endemic areas of Balochistan province. Diagnosis was made on clinical presentation; a giemsa-stained smear test and histopathological results. All the cases were treated with the meglumine antimoniate 600 mg/day (adults) and 15 mg/kg/day (children) intramuscularly for 20 consecutive days. Results All the patients were aged between 2.5 months and 65 years. Three hundred and ninety-two patients were females and 368 were males. Duration of the disease ranged from 2 to 18 months. Most of the patients had a single lesion on the face and/or extremities. Clinically, the disease was classified as: dry papular type, 407 cases; dry ulcerative type, 335 cases; and wet ulcerative type, 18 cases. No cases of muco-cutaneous or visceral leishmaniasis were found during this period. Smear testing was positive in 845 cases, while 365 cases were histopathologically positive. An ultrastructural study was performed using specimens of a few of the cases. Leishmania parasites were detected in the dermal tissues as well as in the macrophages. Conclusions We propose that the Jacobabad, Larkana and Dadu districts could be considered endemic for CL. Wet- and dry-type lesions indicate the presence of both Leishmania tropica and L. major in this tropical region.

81 citations

Journal ArticleDOI
TL;DR: No significant difference was observed in arrest of bleeding in the two groups, but episodes of early rebleeding, blood transfusions, and hospital stay was significantly less in group B.
Abstract: OBJECTIVE: Efficacy of endoscopic variceal sclerotherapy (EVS) alone and in combination with octreotide in controlling acute variceal bleeding and preventing early rebleeding was compared in a double-blind study. METHODS: Consecutive patients presenting with variceal bleeding with low-risk liver cirrhosis were randomized into two groups. Group A received EVS with 3–5 ml of ethanolamine oleate per varix and placebo injection at 50 μg/h; group B received the combined therapy of EVS and octreotide 50 μg/h continuously for 5 days. A total of 70 patients (mean age, 38.4 ± 8.6 yr) were selected for the study, which included 56 men (mean age, 37.9 ± 8.5 yr) and 14 women (mean age, 40.6 ± 9.0 yr). Thirty-five patients were allocated in each group. RESULTS: In group A bleeding was controlled in 30 patients (85.7%) and in group B in 33 (94.3%) (p = 0.24). The number of patients who rebled during the first 5 days after sclerotherapy was eight (22.9%) and two (5.7%) in groups A and B, respectively (p = 0.04). The mean packs of blood transfused to the patients of groups A and B were 2.1 ± 1.2 packs and 1.5 ± 0.7 packs, respectively (p = 0.03). The mean hospital stay of group A was 6.6 ± 1.3 days, whereas that in group B was 5.9 ± 1.2 days (p = 0.04). One patient from each group died during the course of the study. CONCLUSIONS: No significant difference was observed in arrest of bleeding in the two groups, but episodes of early rebleeding, blood transfusions, and hospital stay was significantly less in group B.

59 citations

Journal ArticleDOI
TL;DR: For the proper evaluation of skeletal age in a given region, a longitudinal study on individuals in that region to establish normal standards is necessary.
Abstract: Skeletal maturity in 750 normal Pakistani children (400 males, 350 females) aged 1–18 y was determined by the Greulich–Pyle atlas system. Male children during first year and female children during first 2 y of life matured in conformity with Greulich–Pyle standards. After that period mean bone ages were lower than the American standards up to 15 y in males and 13 y in females (at or around puberty), which may be due to malnutrition, ill health or other environmental factors. After puberty bone ages were higher than the American standards indicating earlier maturity in Pakistani than Western children. Hence for the proper evaluation of skeletal age in a given region, a longitudinal study on individuals in that region to establish normal standards is necessary.

54 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202127
20209
201910
20188
20177
20166