Chandka Medical College

About: Chandka Medical College is a education organization based out in Larkana, Pakistan. It is known for research contribution in the topics: Medicine & Population. The organization has 106 authors who have published 108 publications receiving 1170 citations.

Medico-Legal Cases (MLC) Presented at a Tertiary Care Center and Acute Symptoms of Post-Traumatic Stress Disorder among the Survivors

Abstract: Objectives: An observational, prospective study was conducted to determine the incidence and risk factors associated with victims of physical assault and symptoms of post-traumatic stress disorder (PTSD). Material & Methods: All the registered medico-legal cases reported to the emergency department of Gambat hospital were included in the study. The data was collected on a predefined questionnaire including age, gender, mode of injury, weapon of the injury, type of assault (blunt or penetrating), firearm injuries, and road traffic accidents from medico-legal registers. Impact of Event Scale (IES) was used to assess Post-traumatic stress disorder. Results: The mean age (SD) of victims was 29.3 (10.25) years. Blunt injuries were experienced by 47 (31.33%) victims. The majority of the victims suffered road traffic collision injuries, 59 (39.33%). Forty-eight (32%) victims had substantially higher IES scores (above 37) that confirmed severe PTSD that may contribute to the suppression of the immune system’s functioning among survivors. The majority of the victims were between 18 and 40 years. Conclusion: The most common cases were related to road traffic collisions followed by blunt injuries. The incidence rate of PTSD was also prevalent in these individuals. Thus, strategies should be developed to prevent such incidents and those who suffer from such traumatic events must be offered psychiatric consultation.

Comparison of Lipid Profile in Patients With and Without Subclinical Hypothyroidism.

Abstract: INTRODUCTION Thyroid hormone affects lipid metabolism. Various studies have shown a contradictory relationship between lipid profile (LP) and subclinical hypothyroidism (SCH). Currently, there is a scarcity of regional data on the relationship between LP and SCH. METHODS This longitudinal study was conducted in the internal medicine and cardiology units of a tertiary care hospital in Pakistan from September 2019 to March 2021. A total of 900 participants, of either gender and between the ages of 40 to 70 years, were enrolled in the study. Blood samples were sent to the laboratory to determine lipid and thyroid parameters. Participants were divided into two groups based on the presence of SCH. RESULTS In our study, 179 (19.8%) participants had SCH. Total cholesterol (TC) and low-density lipoprotein (LDL) was significantly higher in participants with SCH compared to participants without SCH (228.41 ± 35.21 mg/dL vs. 171.21 ± 30.21 mg/dL; p-value: <0.00001) and (131.65 ± 28.22 mg/dL vs. 89.26 ± 18.52 mg/dL; p-value: <0.0001), respectively. CONCLUSION In conclusion, this study found an increased incidence of dyslipidemias in patients with SCH. It is associated with elevated TC and LDL levels, which are risk factors for cardiovascular disease and mortality.

Efficacy of low dose intra-dermal hepatitis B vaccination schedule.

Abstract: Efficacy of low-dose, intra-dermal hepatitis B vaccination was assessed among sixty-one doctors and paramedical staff of Chandka Medical College Hospital, Larkana. Subjects were randomly divided into two groups. Group-A (n = 25) received 20 micrograms of purified Hepatitis B Surface Antigen (Euvax B, LG Chemicals) by i.m. injection in the deltoid by 0, 1 and 6 schedule while group B (n = 36) received 5 micrograms intra-dermally by same schedule. The mean value of HBsAb titers checked 4 weeks after the last dose in group A were 158.6 +/- 51.8 mlU/ml and that in Group B were 68.2 +/- 26.6 mlU/ml (p < 0.0001; 95% C.I. 69.2 and 111.5). Number of subjects attaining the protective titers of 10 mlU/ml in group A was 95.7% and that in group B was 90.9% (p = 0.5). We conclude that 5 micrograms intradermal hepatitis B vaccination is effective.

Modern grave robbers

Abstract: What would you do if human bones were an essential part of your medical course but your university could not afford them? Three medics from Pakistan present some ways out of the dilemma The practice of robbing graves to facilitate scientific study of bones and cadavers is nothing new in medicine. In the early 18th century, Britain witnessed a booming trade of exhumed human bodies controlled by grave robbers when anatomy and dissection of the human body became an integral part in study of modern medicine. Because exhuming bodies was considered to be a sacrilege, grave diggers--also known as body snatchers, resurrectionists, or sack ''em up men--became associated with anatomy and surgery departments of medical schools. The practice still persists in many countries across the world, especially developing countries.1–5 In countries such as Pakistan, medical institutions may not be able to afford scientific tools, including bones required for anatomical studies. In Pakistan, anatomy and osteology form a major part of exams and carry a large percentage of marks. There's a widespread belief among students that if you don't have important learning resources your academic career may be jeopardised and without proper anatomical knowledge you are an “incomplete” doctor. However, bones in medical schools are in short supply, and there aren't enough for students to study.6 Medical faculties allow students to study bones only during routine hours and forbid students from taking bones out of the college building. Students therefore feel the necessity to obtain skeletons themselves, as they aren't able to understand osteology in such short spans of time to get a clear picture of human anatomy. As a result, students …

Changing pattern of fabricated injuries in Larkana region.

Abstract: Background: Man has been egotist by nature and from Ancient time man has been endeavouring to bring under power other human beings. With the passage of time and growth of civilization this trend has been increased. Now there are more dangerous ways of violence and torture in use for twisting and turning people around. Inflection of fabricated injuries is one of the ways for fulfilment of his lust. Incidence of fabricated injuries is related with crime rate in any society, and this practice is carried out through out the world. Fabricated Injury is a major problem which forensic expert/causality medical officer face during their duty. Very little literature is available regarding study of fabricated injuries and no authentic criteria has so for been developed for labelling an injury as fabricated one. Methodology: The present study is about 130 challenged medico-legal cases in Larkana Division which were studied in special medical board held in the Department of Urology Chandka Medical College Larkana. Out of 130 cases 50 were proved to be fabricated. Results: The total number of challenged cases was 130, out of these 50 (38.46%) cases were of fabricated injuries. Out of 50 fabricated cases, 46 (92%) were males and 4 (8%) were female, thus the male to female ratio was approximately 11:1. Maximum cases (25) were from Larkana District, 15 cases were from Shikarpur and 10 cases from Jacobabad. The majority of fabricated injuries from Larkana District were nose injuries as o ut of 25 fabricated injuries from Larkana district 10 were nasal injuries, while from district Jacobabad and Shikarpur there was no nasal fabricated injury. Conclusion: Most of the fabricated injuries are caused on accessible part of the body like arms, legs, abdomen, chest etc. The pattern of fabricated injuries is changing in Larkana District as out of 25 fabricated injuries in this district 10 were nasal injuries while in District Jacobabad and Shikarpur there was no nasal fabricated injury. Keywords : Ancient, Fabricated, Injuries, Torture, Endeavouring, Authentic, Egotist