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Institution

Chandka Medical College

EducationLarkana, Pakistan
About: Chandka Medical College is a education organization based out in Larkana, Pakistan. It is known for research contribution in the topics: Population & Outpatient clinic. The organization has 106 authors who have published 108 publications receiving 1170 citations.


Papers
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Journal ArticleDOI
07 Oct 2020-Cureus
TL;DR: It is emphasized that PD, apart from all the motor signs and symptoms, can also present as skin problems, and hence, a multi-disciplinary approach should be taken while managing PD.
Abstract: Background and objective Parkinson's disease (PD) is a common neurodegenerative disorder. There are various manifestations of PD. Among them, motor dysfunction has been studied in many research studies; however, few studies are available related to the dermatological manifestations of PD. This study was conducted with the aim to shed light on various skin conditions that occur in PD. Methods This cross-sectional study was conducted at a tertiary care hospital in Pakistan for a period of nine months; 107 patients with PD were included after obtaining informed consent. A self-administrated questionnaire was used to record demographic data and dermatological findings. Results Among the various dermatological manifestations, patients with PD most commonly presented with seborrheic dermatitis (46.7%) and rosacea (10.2%). Other manifestations included bullous pemphigoid (7.4%) and melanoma (4.6%). Conclusion The study revealed several dermatological manifestations of PD, which usually get overlooked by neurologists. Through this study, we want to emphasize that PD, apart from all the motor signs and symptoms, can also present as skin problems, and hence, a multi-disciplinary approach should be taken while managing PD.

2 citations

Journal ArticleDOI
11 Oct 2019-Cureus
TL;DR: A case of an elderly gentleman presenting with progressive paraplegia, whose diagnosis was delayed as the previous physicians and radiologists missed the underlying key features of SDAVF on magnetic resonance imaging of the spine.
Abstract: Spinal dural arteriovenous fistula (SDAVF) is the most common spinal vascular anomaly. It should always be considered in the differential diagnoses in a patient with progressive paraplegia or quadriplegia. We present a case of an elderly gentleman presenting with progressive paraplegia. The diagnosis was delayed as the previous physicians and radiologists missed the underlying key features of SDAVF on magnetic resonance imaging of the spine. Every neurologist and radiologist should be aware of these signs as SDAVF is mostly a treatable condition.

2 citations

Journal ArticleDOI
17 Jun 2021-Cureus
TL;DR: In this paper, the authors compared the risk of cardiovascular diseases among patients with rheumatoid arthritis (RA) and type 2 diabetes mellitus (DM) and found that RA is a prominent risk factor for cardiovascular events.
Abstract: Introduction Patients with rheumatoid arthritis (RA) have a higher risk of cardiovascular diseases (CVDs) when compared to the general population, with most deaths attributed to myocardial infarctions (MI). However, patients with RA do not get the same attention in terms of cardiovascular screening as compared to other diseases, like diabetes mellitus (DM). Therefore, this study aims to compare the risk of CVD among patients with RA and DM. Methods This prospective study was carried out in Pakistan's two tertiary care hospitals. A total of 750 participants were enrolled in three groups with a 1:1:1 ratio; patients with RA, type 2 DM, and the control group. Patients were observed for 12 months or until the development of a major adverse cardiovascular event (MACE), whichever occurred first. Results Both fatal (12.66% vs. 13.48%; p-value: 0.79) and non-fatal (3.93% vs. 4.35%; p-value: 0.82) MI was comparable between both RA and DM group. However, compared to the control group, non-fatal MI (12.66% vs. 5.58%; p-value: 0.01) was significantly higher in the RA group. Conclusion Our study shows that RA and DM have an equal risk of cardiovascular (CV) events. It is important that RA should be considered as a prominent risk factor for CV events. The management of these patients should be multidisciplinary, including cardiologists.

2 citations

Journal ArticleDOI
05 Jul 2020-Cureus
TL;DR: A case of aHUS associated with Clostridium difficile infection in a 60-year-old female patient that was successfully treated with eculizumab is presented.
Abstract: Atypical hemolytic uremic syndrome (aHUS), defines as non-Shiga toxin HUS, is thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, consumptive thrombocytopenia, and renal impairment aHUS is associated with high morbidity and mortality, necessitating the need for an early diagnosis to limit target organ damage Mutations or autoantibodies against specific complement factors over-activate the complement system forming microthrombi aHUS has the potential to cause multi-organ system dysfunction, but it predominantly affects the kidneys aHUS is treated with eculizumab, a terminal blocker of the complement system Clostridium difficile infection is a rare precipitant of aHUS We present a case of aHUS associated with Clostridium difficile infection in a 60-year-old female patient that was successfully treated with eculizumab

2 citations

Journal ArticleDOI
26 Sep 2020-Cureus
TL;DR: LNF has a significant impact on health-related quality of life and it is important for the physician to consider the impact of GERD in daily life.
Abstract: INTRODUCTION Gastroesophageal reflux disease (GERD) affects various elements of life including sleep, daily and social functioning, and physical and emotional activities. This study aims to determine the impact of laparoscopic Nissen's fundoplication (LNF) on health-related quality of life. METHODS This prospective study was conducted in a tertiary care hospital, Pakistan, from Jan 2019 to Feb 2020. Forty-seven participants completed the study. All patients completed the Gastroesophageal Reflux Disease Health-Related Quality of Life (GERD-HRQoL) questionnaire both pre-operatively and three months after LNF. RESULTS There was significant difference in pre- and post-operative median Health-Related Quality of Life score (p value: 0.0073). There was improvement in items related to heartburn in HRQoL questionnaire, while questions related to swallowing and bloating either showed no change or worsening. CONCLUSION LNF has a significant impact on health-related quality of life. It is important for the physician to consider the impact of GERD in daily life. Management goals for GERD should also include improvement in quality of life of the patient.

2 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202127
20209
201910
20188
20177
20166