Institution
Charité
Healthcare•Berlin, Germany•
About: Charité is a healthcare organization based out in Berlin, Germany. It is known for research contribution in the topics: Population & Transplantation. The organization has 30624 authors who have published 64507 publications receiving 2437322 citations. The organization is also known as: Charite & Charité – University Medicine Berlin.
Topics: Population, Transplantation, Medicine, Cancer, Immune system
Papers published on a yearly basis
Papers
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TL;DR: A neurophysiological predictor of BCI performance is proposed which can be determined from a two minute recording of a 'relax with eyes open' condition using two Laplacian EEG channels.
606 citations
TL;DR: It is suggested that this novel syndrome of X-linked psychomotor retardation is due to a defect in T3 entry into neurons through MCT8, resulting in impaired T3 action and metabolism.
606 citations
TL;DR: Successful reconstitution of CD4(+) T cells at the systemic level as well as in the gut mucosal immune system after CCR5Δ32/Δ 32 stem cell transplantation is demonstrated, suggesting that cure of HIV has been achieved in this patient.
605 citations
TL;DR: In the German health-care system, in which hospital capacities have not been overwhelmed by the COVID-19 pandemic, mortality has been high for patients receiving mechanical ventilation, particularly for patients aged 80 years or older and those requiring dialysis, and has been considerably lower for patients younger than 60 years.
604 citations
TL;DR: This work reports monoallelic frameshift or missense mutations and one 3′ UTR variant of TREX1 present in 9/417 individuals with systemic lupus erythematosus but absent in 1,712 controls, and demonstrates that two mutant TREx1 alleles alter subcellular targeting.
Abstract: TREX1 acts in concert with the SET complex in granzyme A–mediated apoptosis, and mutations in TREX1 cause Aicardi-Goutieres syndrome and familial chilblain lupus. Here, we report monoallelic frameshift or missense mutations and one 3′ UTR variant of TREX1 present in 9/417 individuals with systemic lupus erythematosus but absent in 1,712 controls (P = 4.1 × 10−7). We demonstrate that two mutant TREX1 alleles alter subcellular targeting. Our findings implicate TREX1 in the pathogenesis of SLE.
604 citations
Authors
Showing all 30787 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| JoAnn E. Manson | 270 | 1819 | 258509 |
| Yi Chen | 217 | 4342 | 293080 |
| David J. Hunter | 213 | 1836 | 207050 |
| Raymond J. Dolan | 196 | 919 | 138540 |
| John P. A. Ioannidis | 185 | 1311 | 193612 |
| Stefan Schreiber | 178 | 1233 | 138528 |
| Kenneth C. Anderson | 178 | 1138 | 126072 |
| Eric J. Nestler | 178 | 748 | 116947 |
| Klaus Rajewsky | 154 | 504 | 88793 |
| Charles B. Nemeroff | 149 | 979 | 90426 |
| Andreas Pfeiffer | 149 | 1756 | 131080 |
| Rinaldo Bellomo | 147 | 1714 | 120052 |
| Jean Bousquet | 145 | 1288 | 96769 |
| Christopher Hill | 144 | 1562 | 128098 |
| Holger J. Schünemann | 141 | 810 | 113169 |