Institution
Charles University in Prague
Education•Prague, Czechia•
About: Charles University in Prague is a education organization based out in Prague, Czechia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 32392 authors who have published 74435 publications receiving 1804208 citations.
Topics: Population, Large Hadron Collider, Czech, Magnetization, Transplantation
Papers published on a yearly basis
Papers
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TL;DR: It is shown by combining photoelectron spectroscopy, scanning tunnelling microscopy and density functional theory calculations that Pt single atoms on ceria are stabilized by the most ubiquitous defects on solid surfaces—monoatomic step edges.
Abstract: Single-atom catalysts maximize the utilization of supported precious metals by exposing every single metal atom to reactants. To avoid sintering and deactivation at realistic reaction conditions, single metal atoms are stabilized by specific adsorption sites on catalyst substrates. Here we show by combining photoelectron spectroscopy, scanning tunnelling microscopy and density functional theory calculations that Pt single atoms on ceria are stabilized by the most ubiquitous defects on solid surfaces--monoatomic step edges. Pt segregation at steps leads to stable dispersions of single Pt(2+) ions in planar PtO4 moieties incorporating excess O atoms and contributing to oxygen storage capacity of ceria. We experimentally control the step density on our samples, to maximize the coverage of monodispersed Pt(2+) and demonstrate that step engineering and step decoration represent effective strategies for understanding and design of new single-atom catalysts.
351 citations
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Boston Children's Hospital1, Children's Oncology Group2, St. Jude Children's Research Hospital3, University of Giessen4, Erasmus University Rotterdam5, Umeå University6, Royal Hospital for Sick Children7, Aarhus University Hospital8, Newcastle University9, Ohio State University10, VU University Medical Center11, Jichi Medical University12, Cincinnati Children's Hospital Medical Center13, Charles University in Prague14, Shiga University of Medical Science15, Tokyo Medical and Dental University16, Great Ormond Street Hospital17, First Faculty of Medicine, Charles University in Prague18
TL;DR: Large differences in outcome within 11q23/MLL-rearranged pediatric AML and novel subgroups based on translocation partners that independently predict clinical outcome are identified.
351 citations
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TL;DR: Finite and iterative methods are given, based on results from linear complementarity theory, for computing the exact bounds on the solution of a system of n linear equations in n variables whose coefficients and right-hand sides vary in some real intervals.
349 citations
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National and Kapodistrian University of Athens1, University of Cambridge2, Ludwig Maximilian University of Munich3, Dresden University of Technology4, Leiden University5, Université catholique de Louvain6, University College London7, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico8, University of Pisa9, Karolinska Institutet10, Complutense University of Madrid11, University of Düsseldorf12, Medical University of Vienna13, Charles University in Prague14, Aristotle University of Thessaloniki15, University of Amsterdam16, Academy of Athens17
TL;DR: The EULAR recommendations for the management of LN are updated to facilitate homogenization of patient care and transplantation is the preferred kidney replacement option with immunosuppression guided by transplant protocols and/or extra-renal manifestations.
Abstract: Objective To update the 2012 EULAR/ERA–EDTA recommendations for the management of lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a systematic literature review was performed. Members of a multidisciplinary Task Force voted independently on their level of agreeement with the formed statements. Results The changes include recommendations for treatment targets, use of glucocorticoids and calcineurin inhibitors (CNIs) and management of end-stage kidney disease (ESKD). The target of therapy is complete response (proteinuria 1 g/24 hours despite renin–angiotensin–aldosterone blockade, MMF in combination with glucocorticoids is preferred. Assessment for kidney and extra-renal disease activity, and management of comorbidities is lifelong with repeat kidney biopsy in cases of incomplete response or nephritic flares. In ESKD, transplantation is the preferred kidney replacement option with immunosuppression guided by transplant protocols and/or extra-renal manifestations. Treatment of LN in children follows the same principles as adult disease. Conclusions We have updated the EULAR recommendations for the management of LN to facilitate homogenization of patient care.
349 citations
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TL;DR: Recommendations for the precise estimation of PCR efficiency are proposed: one robust standard curve with at least 3–4 qPCR replicates at each concentration shall be generated, and using a larger volume when constructing serial dilution series reduces sampling error and enables calibration across a wider dynamic range.
349 citations
Authors
Showing all 32719 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ronald C. Petersen | 178 | 1091 | 153067 |
P. Chang | 170 | 2154 | 151783 |
Vaclav Vrba | 141 | 1298 | 95671 |
Milos Lokajicek | 139 | 1511 | 98888 |
Christopher D. Manning | 138 | 499 | 147595 |
Yves Sirois | 137 | 1334 | 95714 |
Rupert Leitner | 136 | 1201 | 90597 |
Gerald M. Reaven | 133 | 799 | 80351 |
Roberto Sacchi | 132 | 1186 | 89012 |
S. Errede | 132 | 1481 | 98663 |
Mark Neubauer | 131 | 1252 | 89004 |
Peter Kodys | 131 | 1262 | 85267 |
Panos A Razis | 130 | 1287 | 90704 |
Vit Vorobel | 130 | 919 | 79444 |
Jehad Mousa | 130 | 1226 | 86564 |