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Institution

Charles University in Prague

EducationPrague, Czechia
About: Charles University in Prague is a education organization based out in Prague, Czechia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 32392 authors who have published 74435 publications receiving 1804208 citations.


Papers
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Journal ArticleDOI
A. Adare1, C. A. Aidala2, C. A. Aidala3, N. N. Ajitanand4  +384 moreInstitutions (56)
TL;DR: Measurements of azimuthal dihadron correlations near midrapidity in d+Au collisions at RHIC and the LHC complement recent analyses by experiments involving central p+Pb collisions at √(s(NN))=5.02 TeV, which have indicated strong anisotropic long-range correlations in angular distributions of hadron pairs.
Abstract: The PHENIX collaboration at the Relativistic Heavy Ion Collider (RHIC) reports measurements of azimuthal dihadron correlations near midrapidity in d + Au collisions at root s(NN) = 200 GeV. These measurements complement recent analyses by experiments at the Large Hadron Collider (LHC) involving central p + Pb collisions at root s(NN) = 5.02 TeV, which have indicated strong anisotropic long-range correlations in angular distributions of hadron pairs. The origin of these anisotropies is currently unknown. Various competing explanations include parton saturation and hydrodynamic flow. We observe qualitatively similar, but larger, anisotropies in d + Au collisions at RHIC compared to those seen in p + Pb collisions at the LHC. The larger extracted upsilon(2) values in d + Au are consistent with expectations from hydrodynamic calculations owing to the larger expected initial-state eccentricity compared with that from p + Pb collisions. When both are divided by an estimate of the initial-state eccentricity the scaled anisotropies follow a common trend with multiplicity that may extend to heavy ion data at RHIC and the LHC, where the anisotropies are widely thought to arise from hydrodynamic flow.

254 citations

Book ChapterDOI
TL;DR: Cladocera is a primarily-freshwater monophyletic group, an important component of the microcrustacean zooplankton, and can be expected to harbour extensive cryptic diversity.
Abstract: Cladocera is a primarily-freshwater monophyletic group, an important component of the microcrustacean zooplankton. They inhabit most types of continental fresh and saline water habitats, occurring more abundantly in both temporary and permanent stagnant waters. Cladocera is an ancient group of Palaeozoic origin. About 620 species are currently known, but we estimate that the real number of species is 2–4 times higher. A number of currently-recognised widespread species can be expected to harbour extensive cryptic diversity.

254 citations

Journal ArticleDOI
TL;DR: Autologous HSCT suggest positive early results in the management of progressive MS and is feasible and is being utilised in the planning of future trials to reduce transplant related mortality.
Abstract: Rationale Phase I/II studies of autologous hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) were initiated, based on results of experimental transplantation in animal models of multiple sclerosis and clinical observations in patients treated concomitantly for malignant disease. Patients Eighty-five patients with progressive MS were treated with autologous HSCT in 20 centers and reported to the autoimmune disease working party of the European Group for Blood and Marrow Transplantation (EBMT). 52 (61 %) were female, median age was 39 [20-58] years. The median interval from diagnosis to transplant was 7 [1-26] years. Patients suffered from severe disease with a median EDSS score of 6.5 [4.5-8.5]. Active disease prior to transplant was documented in 79 of 82 evaluable cases. Results The stem cell source was bone marrow in 6 and peripheral blood in 79, and stem cells were mobilized into peripheral blood using either cyclophosphamide combined with growth factors or growth factors alone. Three patients experienced transient neurological complications during the mobilization phase. The high dose regimen included combination chemotherapy, with or without anti-lymphocyte antibodies or, with or without, total body irradiation. The stem cell transplants were purged of lymphocytes in 52 patients. Median follow-up was 16 [3-59] months. There were 7 deaths, 5 due to toxicity and infectious complications, 2 with neurological deterioration. The risk of death of any cause at 3 years was 10 (±7)% (95 % confidence interval). Neurological deterioration during transplant was observed in 22 patients; this was transient in most but was associated with MS progression in 6 patients. Neurological improvement by ≥ 1 point in the EDSS score was seen in 18 (21 %) patients. Confirmed progression-free survival was 74 (±12)% at 3 years being 66 (±23)% in patients with primary progressive MS but higher in patients with secondary progressive or relapsing-remitting MS, 78 (±13)%; p = 0.59. The probability of confirmed disease progression was 20 (±11)%. MRI data were available in 78 patients before transplant showing disease activity (gadolinium enhancing, new or enlarging lesions) in 33 %. Posttransplant MRI showed activity at any time in 5/61 (8 %) evaluable cases. Conclusion Autologous HSCT suggest positive early results in the management of progressive MS and is feasible. These multicentre data suggest an association with significant mortality risks especially in some patient groups and are being utilised in the planning of future trials to reduce transplant related mortality.

254 citations

Journal ArticleDOI
TL;DR: In this article, a survey of boron-doped diamond electrodes for in vitro/in vivo sensing, or electrochemical detection coupled to conventional or chip-based electrophoretic detection systems is presented.
Abstract: This review with 194 references summarizes the recent progress in the development and applications of boron-doped diamond film electrodes in electroanalysis of organic compounds. It is based on the survey of 106 papers listed in a comprehensive table devoted to batch voltammetric and liquid flow amperometric methods using boron-doped diamond electrodes. The varieties in their construction, surface pre-treatment and electroanalytical methods used are discussed. Special attention is paid to miniaturized boron-doped diamond electrodes for in vitro/in vivo sensing, or electrochemical detection coupled to conventional or chip-based electrophoretic detection systems. Further, possibilities and limitations of surface modification are discussed.

253 citations

Proceedings ArticleDOI
01 Sep 2015
TL;DR: The WMT15 shared task as discussed by the authors included a standard news translation task, a metrics task, tuning task, and a task for run-time estimation of machine translation quality, and an automatic post-editing task.
Abstract: This paper presents the results of the WMT15 shared tasks, which included a standard news translation task, a metrics task, a tuning task, a task for run-time estimation of machine translation quality, and an automatic post-editing task. This year, 68 machine translation systems from 24 institutions were submitted to the ten translation directions in the standard translation task. An additional 7 anonymized systems were included, and were then evaluated both automatically and manually. The quality estimation task had three subtasks, with a total of 10 teams, submitting 34 entries. The pilot automatic postediting task had a total of 4 teams, submitting 7 entries.

253 citations


Authors

Showing all 32719 results

NameH-indexPapersCitations
Ronald C. Petersen1781091153067
P. Chang1702154151783
Vaclav Vrba141129895671
Milos Lokajicek139151198888
Christopher D. Manning138499147595
Yves Sirois137133495714
Rupert Leitner136120190597
Gerald M. Reaven13379980351
Roberto Sacchi132118689012
S. Errede132148198663
Mark Neubauer131125289004
Peter Kodys131126285267
Panos A Razis130128790704
Vit Vorobel13091979444
Jehad Mousa130122686564
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023203
2022554
20214,838
20204,793
20194,421
20183,991