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Institution

Charles University in Prague

EducationPrague, Czechia
About: Charles University in Prague is a education organization based out in Prague, Czechia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 32392 authors who have published 74435 publications receiving 1804208 citations.


Papers
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Journal ArticleDOI
Felix Aharonian1, A. G. Akhperjanian1, A. R. Bazer-Bachi, M. Beilicke1, Wystan Benbow1, David Berge1, Konrad Bernlöhr, Catherine Boisson2, O. Bolz1, V. Borrel, Ilana M. Braun1, F. Breitling, A. M. Brown3, Rolf Bühler1, I. Büsching4, Svenja Carrigan1, P. M. Chadwick3, L.-M. Chounet, R. Cornils1, Luigi Costamante1, B. Degrange, Hugh Dickinson3, A. Djannati-Ataï, L. O'c. Drury5, Guillaume Dubus, Kathrin Egberts1, Dimitrios Emmanoulopoulos6, P. Espigat, F. Feinstein, E. Ferrero6, A. Fiasson, G. Fontaine, Seb. Funk, Stefan Funk1, Y. A. Gallant, B. Giebels, J.F. Glicenstein, P. Goret, C. Hadjichristidis3, D. Hauser1, M. Hauser6, G. Heinzelmann7, Gilles Henri, German Hermann1, Jim Hinton1, Werner Hofmann1, M. Holleran4, Dieter Horns1, A. Jacholkowska, O. C. de Jager4, B. Khélifi, Nu. Komin, A. Konopelko, Karl Kosack1, I. J. Latham3, R. Le Gallou3, Anne Lemiere, M. Lemoine-Goumard, Thomas Lohse, Jean Michel Martin2, Olivier Martineau-Huynh, A. Marcowith, Conor Masterson1, T. J. L. McComb3, M. de Naurois, D. Nedbal1, S. J. Nolan3, A. Noutsos3, K. J. Orford1, J. L. Osborne1, M. Ouchrif, M. Panter1, G. Pelletier, S. Pita, G. Pühlhofer1, Michael Punch, B. C. Raubenheimer4, M. Raue1, S. M. Rayner3, A. Reimer8, Olaf Reimer8, J. Ripken7, L. Rob9, L. Rolland, Gavin Rowell1, V. Sahakian10, L. Saugé, S. Schlenker, Reinhard Schlickeiser8, U. Schwanke, Helene Sol2, D. Spangler3, Felix Spanier8, R. Steenkamp11, C. Stegmann, G. Superina, J.-P. Tavernet, Regis Terrier, C. G. Théoret, M. Tluczykont, C. van Eldik1, G. Vasileiadis, Christo Venter4, P. Vincent, Heinrich J. Völk1, S. J. Wagnern6, Martin Ward3 
TL;DR: In this paper, the Crab nebula was observed with the H.E.S. stereoscopic Cherenkov-telescope array between 2003 and 2005 for a total of 22.9 hours (after data quality selection).
Abstract: The Crab nebula was observed with the H.E.S.S. stereoscopic Cherenkov-telescope array between October 2003 and January 2005 for a total of 22.9 hours (after data quality selection). Observations were made with three operational telescopes in late 2003 and with the complete 4 telescope array in January - February 2004 and October 2004 - January 2005. The observations are discussed and used as an example to detail the flux and spectral analysis procedures of H.E.S.S., and to evaluate the systematic uncertainties in H.E.S.S. flux measurements. The flux and spectrum of gamma-rays from the source are calculated on run-by-run and monthly time-scales, and a correction is applied for long-term variations in the detector sensitivity. Comparisons of the measured flux and spectrum over the observation period, along with the results from a number of different analysis procedures are used to estimate systematic uncertainties in the measurements. The energy spectrum is found to follow a power law with an exponential cutoff, with photon index $\Gamma = 2.39 \pm 0.03\stat$ and cutoff energy $E_{c} = (14.3 \pm 2.1\stat) \textrm{TeV}$ between 440 GeV and 40 TeV. The observed integral flux above 1 TeV is $(2.26 \pm 0.08\stat) \times 10^{-11} cm^{-2} s^{-1}$. The estimated systematic error on the flux measurement is estimated to be 20%, while the estimated systematic error on the spectral slope is 0.1.

699 citations

Journal ArticleDOI
Andrea Cossarizza1, Hyun-Dong Chang, Andreas Radbruch, Andreas Acs2  +459 moreInstitutions (160)
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.
Abstract: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.

698 citations

Journal ArticleDOI
TL;DR: Cangrelor significantly reduced the rate of ischemic events, including stent thrombosis, during PCI, with no significant increase in severe bleeding.
Abstract: Background The intensity of antiplatelet therapy during percutaneous coronary intervention (PCI) is an important determinant of PCI-related ischemic complications. Cangrelor is a potent intravenous adenosine diphosphate (ADP)–receptor antagonist that acts rapidly and has quickly reversible effects. Methods In a double-blind, placebo-controlled trial, we randomly assigned 11,145 patients who were undergoing either urgent or elective PCI and were receiving guideline-recommended therapy to receive a bolus and infusion of cangrelor or to receive a loading dose of 600 mg or 300 mg of clopidogrel. The primary efficacy end point was a composite of death, myocardial infarction, ischemia-driven revascularization, or stent thrombosis at 48 hours after randomization; the key secondary end point was stent thrombosis at 48 hours. The primary safety end point was severe bleeding at 48 hours. Results The rate of the primary efficacy end point was 4.7% in the cangrelor group and 5.9% in the clopidogrel group (adjusted od...

694 citations

Journal ArticleDOI
TL;DR: It is shown that not only are the search queries and the prices connected but there also exists a pronounced asymmetry between the effect of an increased interest in the currency while being above or below its trend value.
Abstract: Digital currencies have emerged as a new fascinating phenomenon in the financial markets. Recent events on the most popular of the digital currencies – BitCoin – have risen crucial questions about behavior of its exchange rates and they offer a field to study dynamics of the market which consists practically only of speculative traders with no fundamentalists as there is no fundamental value to the currency. In the paper, we connect two phenomena of the latest years – digital currencies, namely BitCoin, and search queries on Google Trends and Wikipedia – and study their relationship. We show that not only are the search queries and the prices connected but there also exists a pronounced asymmetry between the effect of an increased interest in the currency while being above or below its trend value.

692 citations


Authors

Showing all 32719 results

NameH-indexPapersCitations
Ronald C. Petersen1781091153067
P. Chang1702154151783
Vaclav Vrba141129895671
Milos Lokajicek139151198888
Christopher D. Manning138499147595
Yves Sirois137133495714
Rupert Leitner136120190597
Gerald M. Reaven13379980351
Roberto Sacchi132118689012
S. Errede132148198663
Mark Neubauer131125289004
Peter Kodys131126285267
Panos A Razis130128790704
Vit Vorobel13091979444
Jehad Mousa130122686564
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023203
2022554
20214,838
20204,793
20194,421
20183,991