Institution
Charles University in Prague
Education•Prague, Czechia•
About: Charles University in Prague is a education organization based out in Prague, Czechia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 32392 authors who have published 74435 publications receiving 1804208 citations.
Topics: Population, Large Hadron Collider, Czech, Magnetization, Transplantation
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University of Texas Southwestern Medical Center1, University of Glasgow2, Harvard University3, Novartis4, Université de Montréal5, Medical University of South Carolina6, University of Iceland7, University of Western Ontario8, Charles University in Prague9, Saarland University10, Stellenbosch University11, University of Santiago de Compostela12, National Yang-Ming University13, Comenius University in Bratislava14, University of Latvia15, University of Gothenburg16, Universidad Autónoma de Santo Domingo17, University of Paris18, Nanjing Medical University19, Khon Kaen University20, Catholic University of Daegu21, Dokuz Eylül University22, National University of Cordoba23, Semmelweis University24, Central University of Venezuela25, Wrocław Medical University26, University of Eastern Finland27, University of São Paulo28, Aarhus University29, University of Porto30, University of Leicester31, Cleveland Clinic32, University of California, San Francisco33, Katholieke Universiteit Leuven34, Carol Davila University of Medicine and Pharmacy35
TL;DR: Angiotensin-neprilysin inhibition prevents the clinical progression of surviving patients with heart failure more effectively than angiotens in-converting enzyme inhibition.
Abstract: Background—Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known about the effect of drugs ...
532 citations
Charles University in Prague1, Google2, University of Trento3, National Institute of Information and Communications Technology4, University of Barcelona5, Polytechnic University of Catalonia6, New York University7, Uppsala University8, University of Stuttgart9, Stanford University10, Brandeis University11, Saarland University12
TL;DR: This shared task combines the shared tasks of the previous five years under a unique dependency-based formalism similar to the 2008 task and describes how the data sets were created and show their quantitative properties.
Abstract: For the 11th straight year, the Conference on Computational Natural Language Learning has been accompanied by a shared task whose purpose is to promote natural language processing applications and evaluate them in a standard setting. In 2009, the shared task was dedicated to the joint parsing of syntactic and semantic dependencies in multiple languages. This shared task combines the shared tasks of the previous five years under a unique dependency-based formalism similar to the 2008 task. In this paper, we define the shared task, describe how the data sets were created and show their quantitative properties, report the results and summarize the approaches of the participating systems.
531 citations
University of Cologne1, Charles University in Prague2, Heidelberg University3, Masaryk University4, University of Tübingen5, University of Ulm6, Charité7, Ludwig Maximilian University of Munich8, University of Würzburg9, University of Hamburg10, University of Duisburg-Essen11, Leipzig University12, University of Münster13, University of Salzburg14, University Hospital Regensburg15, Saarland University16
TL;DR: Treatment with six cycles of BEACOPP(escalated) followed by PET-guided radiotherapy was more effective in terms of freedom from treatment failure and less toxic than eight cycles of the same chemotherapy regimen, and should be the treatment of choice for advanced stage Hodgkin's lymphoma.
528 citations
TL;DR: This work mapped cis- and trans-regulatory control elements for expression of thousands of genes across the genome in the BXH/HXB panel of rat recombinant inbred strains and generated a data set of 73 candidate genes for hypertension that merit testing in human populations.
Abstract: Integration of genome-wide expression profiling with linkage analysis is a new approach to identifying genes underlying complex traits. We applied this approach to the regulation of gene expression in the BXH/HXB panel of rat recombinant inbred strains, one of the largest available rodent recombinant inbred panels and a leading resource for genetic analysis of the highly prevalent metabolic syndrome. In two tissues important to the pathogenesis of the metabolic syndrome, we mapped cis- and trans-regulatory control elements for expression of thousands of genes across the genome. Many of the most highly linked expression quantitative trait loci are regulated in cis, are inherited essentially as monogenic traits and are good candidate genes for previously mapped physiological quantitative trait loci in the rat. By comparative mapping we generated a data set of 73 candidate genes for hypertension that merit testing in human populations. Mining of this publicly available data set is expected to lead to new insights into the genes and regulatory pathways underlying the extensive range of metabolic and cardiovascular disease phenotypes that segregate in these recombinant inbred strains.
527 citations
Max Planck Society1, Yerevan Physics Institute2, Centre national de la recherche scientifique3, University of Hamburg4, Humboldt University of Berlin5, Durham University6, École Polytechnique7, University of Paris8, Dublin Institute for Advanced Studies9, University of Montpellier10, Joseph Fourier University11, DSM12, North-West University13, Ruhr University Bochum14, Charles University in Prague15, University of Namibia16
TL;DR: In this paper, a very high-energy γ-ray emission from the Galactic Centre region has been measured using HESS, the High Energy Stereoscopic System recently constructed in Namibia, South West Africa.
Abstract: Events at the centre of our Galaxy are key to our understanding of high-energy processes in the Universe, since it contains examples of virtually every type of exotic object known to astronomers. The very-high-energy γ-ray emission from the Galactic Centre region has now been measured using HESS, the High Energy Stereoscopic System recently constructed in Namibia, South West Africa. HESS operates at energies above the regime accessible to satellite-based detectors, taking γ-ray astronomy into new territory. The results show that these clouds are glowing in very high energy γ-rays. The glow is caused by constant bombardment of the clouds by cosmic rays — probably protons and nuclei — produced close to the central black hole or in the expanding blast waves of supernova explosions. The source of Galactic cosmic rays (with energies up to 1015 eV) remains unclear, although it is widely believed that they originate in the shock waves of expanding supernova remnants1,2. At present the best way to investigate their acceleration and propagation is by observing the γ-rays produced when cosmic rays interact with interstellar gas3. Here we report observations of an extended region of very-high-energy (> 1011 eV) γ-ray emission correlated spatially with a complex of giant molecular clouds in the central 200 parsecs of the Milky Way. The hardness of the γ-ray spectrum and the conditions in those molecular clouds indicate that the cosmic rays giving rise to the γ-rays are likely to be protons and nuclei rather than electrons. The energy associated with the cosmic rays could have come from a single supernova explosion around 104 years ago.
527 citations
Authors
Showing all 32719 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Ronald C. Petersen | 178 | 1091 | 153067 |
| P. Chang | 170 | 2154 | 151783 |
| Vaclav Vrba | 141 | 1298 | 95671 |
| Milos Lokajicek | 139 | 1511 | 98888 |
| Christopher D. Manning | 138 | 499 | 147595 |
| Yves Sirois | 137 | 1334 | 95714 |
| Rupert Leitner | 136 | 1201 | 90597 |
| Gerald M. Reaven | 133 | 799 | 80351 |
| Roberto Sacchi | 132 | 1186 | 89012 |
| S. Errede | 132 | 1481 | 98663 |
| Mark Neubauer | 131 | 1252 | 89004 |
| Peter Kodys | 131 | 1262 | 85267 |
| Panos A Razis | 130 | 1287 | 90704 |
| Vit Vorobel | 130 | 919 | 79444 |
| Jehad Mousa | 130 | 1226 | 86564 |