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Institution

Charles University in Prague

EducationPrague, Czechia
About: Charles University in Prague is a education organization based out in Prague, Czechia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 32392 authors who have published 74435 publications receiving 1804208 citations.


Papers
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Journal ArticleDOI
TL;DR: Wright et al. as mentioned in this paper show that wiele korzyści wynikających z dzialania witaminy D na organizm czlowieka na wszystkichetapach jego zycia wiekszośc badan epidemiologicznych sugeruje, ze niedobor witaminą D, ktore przeslano do czlonkow Komitetu Naukowego konfere
Abstract: Wstep: Wyniki badan z ostatnich lat dokumentują wiele korzyści wynikających z dzialania witaminy D na organizm czlowieka na wszystkichetapach jego zycia Wiekszośc badan epidemiologicznych sugeruje, ze niedobor witaminy D jest powszechny wśrod mieszkancow EuropyŚrodkowej Naturalną konsekwencją tej sytuacji jest koniecznośc ciąglego uświadamiania spoleczenstwu oraz środowisku medycznemu,jaką role odgrywa witamina D w rozwoju i funkcjonowaniu organizmu ludzkiego Metody: Na podstawie przeglądu danych literaturowych Polski Zespol Wielodyscyplinarny opracowal tezy dotyczące zasad suplementacjiwitaminą D, ktore przeslano do czlonkow Komitetu Naukowego konferencji „Witamina D — minimum, maksimum, optimum”,19–20 Październik, 2012, Warszawa W trakcie powyzszej konferencji z udzialem 550 delegatow oraz Ekspertow roznych dziedzin medycynyomowiono i przedyskutowano propozycje wytycznych suplementacji witaminą D populacji Europy Środkowej Wyniki: W efekcie przeprowadzonych dyskusji Zespol Ekspertow opracowal wytyczne suplementacji witaminą D dla wszystkich grupwiekowych populacji Europy Środkowej Określono rowniez kryteria diagnostyczne charakteryzujące stan zaopatrzenia organizmu w witamine D: deficyt witaminy D ustalono jako stezenie 25(OH)D < 20 ng/mL (< 50 nmol/L)], suboptymalne zaopatrzenie jako stezenie25(OH)D wynoszące 20–30 ng/mL (50–75 nmol/L), a stezenie 30–50 ng/mL (75–125 nmol/L) uznano za docelowe dla zapewnienia efektuplejotropowego witaminy D Wnioski: Poprawa obecnego stanu zaopatrzenia witaminy D w grupach dzieci, mlodziezy, osob aktywnych zawodowo i seniorowpowinna zostac wlączona do priorytetow polityki zdrowotnej spoleczenstw Europy Środkowej

415 citations

Journal ArticleDOI
J. Abraham1, P. Abreu2, Marco Aglietta3, Marco Aglietta4  +480 moreInstitutions (79)
TL;DR: In this paper, the Pierre Auger Observatory data was used to confirm the anisotropy of the arrival direction of the highest-energy cosmic rays with the highest energy, which are correlated with the positions of relatively nearby active galactic nuclei (AGN) at a confidence level of more than 99%.

415 citations

Journal ArticleDOI
TL;DR: This review is focused upon contemporary information on the changes in leaf structure, water relations and photosynthesis during acclimatization of plantlets to ex vitro conditions and some ways of improving plant survival and for the speeding up of acclimation.
Abstract: The special conditions during in vitro culture result in the formation of plantlets of abnormal morphology, anatomy and physiology. After ex vitro transfer, these plantlets might easily be impaired by sudden changes in environmental conditions, and so need a period of acclimatization to correct the abnormalities. This review is focused upon contemporary information on the changes in leaf structure, water relations and photosynthesis during acclimatization of plantlets to ex vitro conditions. It also describes some ways of improving plant survival and for the speeding up of acclimatization.

414 citations

Journal ArticleDOI
Claus Meyer1, Julia Hofmann1, Thomas Burmeister2, Daniela Gröger2, T S Park3, Mariana Emerenciano, M. Pombo De Oliveira, Aline Renneville4, Patrick Villarese5, Elizabeth Macintyre5, Hélène Cavé5, Emmanuelle Clappier5, K. Mass-Malo5, Jan Zuna6, Jan Trka6, E De Braekeleer7, M. De Braekeleer7, S H Oh8, Grigory Tsaur, L Fechina, V H J van der Velden9, J J M van Dongen9, Eric Delabesse, Renata Binato, Mara Silva, AM Kustanovich, Olga V. Aleinikova, Marian H. Harris10, T Lund-Aho, Vesa Juvonen11, Olaf Heidenreich12, Josef Vormoor12, William W.L. Choi13, Marie Jarošová, A. Kolenova14, Clara Bueno15, Pablo Menendez15, S. Wehner1, Cornelia Eckert2, Pascaline Talmant16, Sylvie Tondeur, Eric Lippert, E. Launay17, Catherine Henry17, Paola Ballerini18, H. Lapillone18, Mary Callanan19, Jean Michel Cayuela5, Charles Herbaux, Giovanni Cazzaniga20, P. M. Kakadiya21, Stefan K. Bohlander21, Martina Ahlmann, Jong Rak Choi22, Paula Gameiro23, Dongsoon Lee24, Juergen Krauter25, Pascale Cornillet-Lefebvre, G te Kronnie26, Beat W. Schäfer27, S. Kubetzko27, Cristina N. Alonso, U. Zur Stadt28, Rosemary Sutton29, N. C. Venn29, Shai Izraeli30, Luba Trakhtenbrot31, H. O. Madsen32, P. Archer33, Jeremy Hancock33, Nuno Cerveira34, Manuel R. Teixeira34, L Lo Nigro35, Anja Möricke36, Martin Stanulla36, Martin Schrappe36, Lukasz Sedek37, Tomasz Szczepański37, Christian M. Zwaan9, Eva A. Coenen9, M.M. van den Heuvel-Eibrink9, Sabine Strehl38, Michael Dworzak38, Renate Panzer-Grümayer38, Theodor Dingermann1, Thomas Klingebiel1, Rolf Marschalek1 
30 Apr 2013-Leukemia
TL;DR: Long-distance inverse-polymerase chain reaction was used to characterize the chromosomal rearrangement of individual acute leukemia patients and revealed a total of 121 different MLL rearrangements, of which 79 TPGs are now characterized at the molecular level.
Abstract: Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are associated with high-risk infant, pediatric, adult and therapy-induced acute leukemias. We used long-distance inverse-polymerase chain reaction to characterize the chromosomal rearrangement of individual acute leukemia patients. We present data of the molecular characterization of 1590 MLL-rearranged biopsy samples obtained from acute leukemia patients. The precise localization of genomic breakpoints within the MLL gene and the involved translocation partner genes (TPGs) were determined and novel TPGs identified. All patients were classified according to their gender (852 females and 745 males), age at diagnosis (558 infant, 416 pediatric and 616 adult leukemia patients) and other clinical criteria. Combined data of our study and recently published data revealed a total of 121 different MLL rearrangements, of which 79 TPGs are now characterized at the molecular level. However, only seven rearrangements seem to be predominantly associated with illegitimate recombinations of the MLL gene (∼90%): AFF1/AF4, MLLT3/AF9, MLLT1/ENL, MLLT10/AF10, ELL, partial tandem duplications (MLL PTDs) and MLLT4/AF6, respectively. The MLL breakpoint distributions for all clinical relevant subtypes (gender, disease type, age at diagnosis, reciprocal, complex and therapy-induced translocations) are presented. Finally, we present the extending network of reciprocal MLL fusions deriving from complex rearrangements.

414 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek4  +2815 moreInstitutions (169)
TL;DR: In this article, a search for new phenomena in final states with an energetic jet and large missing transverse momentum was performed using 20.3 fb(-1) of root s = 8 TeV data collected in 2012.
Abstract: Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb(-1) of root s = 8 TeV data collected in 2012 ...

414 citations


Authors

Showing all 32719 results

NameH-indexPapersCitations
Ronald C. Petersen1781091153067
P. Chang1702154151783
Vaclav Vrba141129895671
Milos Lokajicek139151198888
Christopher D. Manning138499147595
Yves Sirois137133495714
Rupert Leitner136120190597
Gerald M. Reaven13379980351
Roberto Sacchi132118689012
S. Errede132148198663
Mark Neubauer131125289004
Peter Kodys131126285267
Panos A Razis130128790704
Vit Vorobel13091979444
Jehad Mousa130122686564
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023203
2022554
20214,838
20204,793
20194,421
20183,991