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Child In Need Institute

NonprofitKolkata, West Bengal, India
About: Child In Need Institute is a nonprofit organization based out in Kolkata, West Bengal, India. It is known for research contribution in the topics: Population & Public health. The organization has 29 authors who have published 25 publications receiving 388 citations. The organization is also known as: CINI.

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Journal ArticleDOI
TL;DR: Evidence supports the acceptability of phenobarbital as a first-line drug for childhood epilepsy in rural settings in developing countries.

126 citations

Journal ArticleDOI
TL;DR: Women from northeast India, particularly from Manipur, appear less susceptible to HPV16/18 infection and related cervical lesions compared to those from West Bengal, where such proneness was prominently evident at age ≤30 years.
Abstract: Human papillomavirus (HPV) DNA in cervical scrape samples of married women from Manipur (n= 692) and Sikkim (n= 415) in northeast India was determined and compared with that of women from West Bengal (n= 1112) in eastern India by polymerase chain reaction. HPV prevalence was lower in Manipur (7.4%) than in Sikkim (12.5%), which was closely followed by West Bengal (12.9%). HPV18 was predominant in Manipur (2.03%) and strikingly lower (0.2%) in Sikkim and West Bengal (0.9%), while the reverse was true for HPV16. The proportion of HPV16/18 infections in Manipur (3.3%, 22/672) and Sikkim (3.89%, 14/359) were comparable and significantly lower compared to that in West Bengal (7.8%, 79/1007) among women having normal cervical cytology. Such prevalence was similar among all age groups in Manipur: increased with age for women in Sikkim and dropped with age for those in West Bengal similar to that reported previously. At age ≤30 years, HPV16/18 prevalence in Manipur (3.3%) and Sikkim (2.5%) was comparable but was significantly lower (P 30 years and equally among those in West Bengal aged ≤30 or >30 years. Thus, women from northeast India, particularly from Manipur, appear less susceptible to HPV16/18 infection and related cervical lesions compared to those from West Bengal, where such proneness was prominently evident at age ≤30 years.

67 citations

Journal ArticleDOI
TL;DR: The data show that these Indian Muslim women are equally susceptible to HPV16/18 infection and for the development of abnormal cytology, which justifies the need to screen women of all religions for cervical cancer.
Abstract: Muslim women are known to have lower incidences of cervical cancer and/or human papillomavirus (HPV) infection. Here we aim to determine any association that may be present between the oncogenic HPV16/18 infections and abnormal cytological lesions along with demographic and other attributes among Indian Muslim women (n = 478) and compare with the neighboring Hindus (n = 534) from a prospective cohort study. Agewise distribution of both subject-groups is similar. HPV16/18 infection is present in 9.6% Muslims and 7.5% Hindu women. Jointly atypical cells of undetermined significance (a typical cells of undetermined significance) and HPV16/18 are present in seven Muslim and two Hindu women. No high squamous intraepithelial lesions or cervical cancer is detected at the baseline. HPV16/18 infections show trends that varied with age, a nonlinear trend among Muslim women. In Hindu women the prevalence is highest at age ≤24 years, which linearly drops with increasing age. Abnormal cytology increases significantly in both religion-groups with increasing age. The data show that these Indian Muslim women are equally susceptible to HPV16/18 infection and for the development of abnormal cytology. There is a paucity in epidemiological data, which justifies the need to screen women of all religions for cervical cancer (that includes oncogenic HPV testing).

36 citations

Journal ArticleDOI
TL;DR: This study aimed to explore the attitude of affluent, urban Indian parents towards the HPV vaccine and the social structure in India will not permit vaccination of this age‐group without parental approval.
Abstract: AIM: The human papillomavirus (HPV) vaccine is recommended for adolescent girls and young women; however the social structure in India will not permit vaccination of this age-group without parental approval. Our study aimed to explore the attitude of affluent urban Indian parents towards the HPV vaccine. METHODS: Well-to-do married couples with at least one daughter between 9-26 years of age were interviewed using a questionnaire in two parts. The first part was to assess their attitude to vaccination in general and their knowledge of cervical cancer; the second part was to assess their acceptance of the HPV vaccine. An educational fact sheet about cervical cancer and the HPV vaccine was administered in between the two parts. RESULTS: Of the 522 participants 27% of men and 24% of women agreed to vaccinate their daughters against a cancer initially. After going through the fact sheet 74% of both men and women were in favor of vaccination. CONCLUSIONS: The HPV vaccine seems to be well accepted among this subgroup of population if appropriately educated. (c) 2011 The Authors. Journal of Obstetrics and Gynaecology Research (c) 2011 Japan Society of Obstetrics and Gynecology.

34 citations

Journal ArticleDOI
22 Jun 2018-BMJ Open
TL;DR: The primary hypothesis is that infants receiving LEAP-CP will have greater scaled scores on the Pediatric Evaluation of Disability Inventory—Computer Adaptive Test (mobility domain) at 18 months compared with health advice.
Abstract: Introduction Cerebral palsy (CP) is the most common childhood physical disability, with 80% estimated to be in low-middle-income countries. This study aims to (1) determine the accuracy of General Movements (GMs)/Hammersmith Infant Neurological Examination (HINE) for detecting CP at 18 months corrected age (CA); (2) determine the effectiveness of a community-based parent-delivered early intervention for infants at high risk of CP in West Bengal, India (Learning through Everyday Activities with Parents for infants with CP; LEAP-CP). Methods This study comprises two substudies: (1) a study of the predictive validity of the GMs and HINE for detecting CP; (2) randomised, double-blinded controlled trial of a novel intervention delivered through peer trainers (Community Disability Workers, CDW) compared with health advice (15 fortnightly visits). 142 infants at high risk of CP (‘absent fidgety’ GMs; ‘high risk score’ on HINE) aged 12–40 weeks CA will be recruited to the intervention substudy, with infants randomised based on a computer-generated sequence. Researchers will be masked to group allocation, and caregivers and CDWs naive to intervention status. Visits will include therapeutic modules (goal-directed active motor/cognitive strategies and LEAP-CP games) and parent education. Health advice is based on the Integrated Management of Childhood Illness, WHO. Infants will be evaluated at baseline, post intervention and 18 months CA. The primary hypothesis is that infants receiving LEAP-CP will have greater scaled scores on the Pediatric Evaluation of Disability Inventory—Computer Adaptive Test (mobility domain) at 18 months compared with health advice. Secondary outcomes include infant functional motor, cognitive, visual and communication development; infant growth; maternal mental health. Ethics and dissemination This study is approved through appropriate Australian and Indian ethics committees (see in text) with families providing written informed consent. Findings from this trial will be disseminated through peer-reviewed journal publications and conference presentations. Trial registration number 12616000653460p; Pre-results.

27 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20211
20201
20193
20181
20171
20162