China University of Political Science and Law

About: China University of Political Science and Law is a education organization based out in Beijing, China. It is known for research contribution in the topics: China & Population. The organization has 1005 authors who have published 1087 publications receiving 5922 citations. The organization is also known as: Peking College of Political Science and Law & CUPL.

A global analysis of Y-chromosomal haplotype diversity for 23 STR loci

Abstract: In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.

Democratization and the Middle Class in China The Middle Class’s Attitudes toward Democracy

Abstract: Do the middle classes in authoritarian, late-developing countries support democratization? Among scholars, there seems no clear consensus on this question. To fill this gap, this article examines the case of the middle class in China, based on data collected from a probability-sample survey. The findings from this study indicate (1) the middle class does not necessarily support democratization in authoritarian developing countries, (2) there is a negative correlation between the middle class’s dependence on the state and its support for democracy, and (3) the middle class’s perceived social and economic well-being is also negatively associated with its democratic support.

Scalable and Privacy-Preserving Data Sharing Based on Blockchain

Abstract: With the development of network technology and cloud computing, data sharing is becoming increasingly popular, and many scholars have conducted in-depth research to promote its flourish. As the scale of data sharing expands, its privacy protection has become a hot issue in research. Moreover, in data sharing, the data is usually maintained in multiple parties, which brings new challenges to protect the privacy of these multi-party data. In this paper, we propose a trusted data sharing scheme using blockchain. We use blockchain to prevent the shared data from being tampered, and use the Paillier cryptosystem to realize the confidentiality of the shared data. In the proposed scheme, the shared data can be traded, and the transaction information is protected by using the (p, t)-threshold Paillier cryptosystem. We conduct experiments in cloud storage scenarios and the experimental results demonstrate the efficiency and effectiveness of the proposed scheme.

From resilience to resistance: A reconstruction of the strengths perspective in social work practice

Abstract: Many practice models in social work focus primarily on the concepts associated with resilience. By contrast, resistance and rebellion, important strategies of the disadvantaged, are often neglected...

Traumatic brain injury dysregulates microRNAs to modulate cell signaling in rat hippocampus.

Abstract: Traumatic brain injury (TBI) is a common cause for cognitive and communication problems, but the molecular and cellular mechanisms are not well understood. Epigenetic modifications, such as microRNA (miRNA) dysregulation, may underlie altered gene expression in the brain, especially hippocampus that plays a major role in spatial learning and memory and is vulnerable to TBI. To advance our understanding of miRNA in pathophysiological processes of TBI, we carried out a time-course microarray analysis of microRNA expression profile in rat ipsilateral hippocampus and examined histological changes, apoptosis and synapse ultrastructure of hippocampus post moderate TBI. We found that 10 out of 156 reliably detected miRNAs were significantly and consistently altered from one hour to seven days after injury. Bioinformatic and gene ontology analyses revealed 107 putative target genes, as well as several biological processes that might be initiated by those dysregulated miRNAs. Among those differentially expressed microRNAs, miR-144, miR-153 and miR-340-5p were confirmed to be elevated at all five time points after TBI by quantitative RT-PCR. Western blots showed three of the predicated target proteins, calcium/calmodulin-dependent serine protein kinase (CASK), nuclear factor erythroid 2-related factor 2 (NRF2) and alpha-synuclein (SNCA), were concurrently down- regulated, suggesting that miR-144, miR-153 and miR-340-5p may play important roles collaboratively in the pathogenesis of TBI-induced cognitive and memory impairments. These microRNAs might serve as potential targets for progress assessment and intervention against TBI to mitigate secondary damage to the brain.