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Chinese Academy of Sciences

GovernmentBeijing, Beijing, China
About: Chinese Academy of Sciences is a(n) government organization based out in Beijing, Beijing, China. It is known for research contribution in the topic(s): Catalysis & Population. The organization has 421602 authors who have published 634849 publication(s) receiving 14894293 citation(s). The organization is also known as: CAS. more

Topics: Catalysis, Population, Laser more

Showing all 421602 results

Frank B. Hu2501675253464
Zhong Lin Wang2452529259003
Yi Chen2174342293080
Jing Wang1844046202769
Peidong Yang183562144351
Xiaohui Fan183878168522
H. S. Chen1792401178529
Douglas Scott1781111185229
Jie Zhang1784857221720
Pulickel M. Ajayan1761223136241
Feng Zhang1721278181865
Andrea Bocci1722402176461
Yang Yang1712644153049
Lei Jiang1702244135205
Yang Gao1682047146301

Open accessJournal ArticleDOI: 10.1093/BIOINFORMATICS/BTP352
Heng Li1, Bob Handsaker2, Alec Wysoker2, T. J. Fennell2  +5 moreInstitutions (4)
01 Aug 2009-Bioinformatics
Abstract: Summary: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style, compact in size, efficient in random access and is the format in which alignments from the 1000 Genomes Project are released. SAMtools implements various utilities for post-processing alignments in the SAM format, such as indexing, variant caller and alignment viewer, and thus provides universal tools for processing read alignments. Availability: Contact: [email protected] more

Topics: Variant Call Format (62%), Stockholm format (61%), FASTQ format (56%) more

35,747 Citations

Open accessJournal ArticleDOI: 10.1038/35057062
Eric S. Lander1, Lauren Linton1, Bruce W. Birren1, Chad Nusbaum1  +245 moreInstitutions (29)
15 Feb 2001-Nature
Abstract: The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence. more

Topics: Cancer genome sequencing (61%), Hybrid genome assembly (59%), Cancer Genome Project (58%) more

21,023 Citations

Open accessJournal ArticleDOI: 10.1016/S0140-6736(20)30211-7
Nanshan Chen1, Min Zhou2, Xuan Dong1, Jie-Ming Qu2  +10 moreInstitutions (3)
30 Jan 2020-The Lancet
Abstract: In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia. In this retrospective, single-centre study, we included all confirmed cases of 2019-nCoV in Wuhan Jinyintan Hospital from Jan 1 to Jan 20, 2020. Cases were confirmed by real-time RT-PCR and were analysed for epidemiological, demographic, clinical, and radiological features and laboratory data. Outcomes were followed up until Jan 25, 2020. more

12,381 Citations

Open accessJournal ArticleDOI: 10.1038/S41586-020-2012-7
Peng Zhou1, Xing-Lou Yang1, Xian Guang Wang2, Ben Hu1  +25 moreInstitutions (3)
03 Feb 2020-Nature
Abstract: Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats1–4. Previous studies have shown that some bat SARSr-CoVs have the potential to infect humans5–7. Here we report the identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China. The epidemic, which started on 12 December 2019, had caused 2,794 laboratory-confirmed infections including 80 deaths by 26 January 2020. Full-length genome sequences were obtained from five patients at an early stage of the outbreak. The sequences are almost identical and share 79.6% sequence identity to SARS-CoV. Furthermore, we show that 2019-nCoV is 96% identical at the whole-genome level to a bat coronavirus. Pairwise protein sequence analysis of seven conserved non-structural proteins domains show that this virus belongs to the species of SARSr-CoV. In addition, 2019-nCoV virus isolated from the bronchoalveolar lavage fluid of a critically ill patient could be neutralized by sera from several patients. Notably, we confirmed that 2019-nCoV uses the same cell entry receptor—angiotensin converting enzyme II (ACE2)—as SARS-CoV. Characterization of full-length genome sequences from patients infected with a new coronavirus (2019-nCoV) shows that the sequences are nearly identical and indicates that the virus is related to a bat coronavirus. more

Topics: Coronavirus (67%), Betacoronavirus (54%), Deltacoronavirus (51%) more

12,056 Citations

Open accessJournal ArticleDOI: 10.1056/NEJMOA2001316
Qun Li1, Xuhua Guan1, Peng Wu2, Xiaoye Wang1  +43 moreInstitutions (6)
Abstract: Background The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the... more

Topics: Coronavirus (54%)

10,234 Citations

No. of papers from the Institution in previous years

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Institution's top 5 most impactful journals


6K papers, 8.9K citations

Chinese Science Bulletin

4.9K papers, 73.5K citations

Scientific Reports

4.7K papers, 141.5K citations

RSC Advances

4.3K papers, 77.3K citations

Science of The Total Environment

3.9K papers, 96.5K citations

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