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Institution

Chinese Center for Disease Control and Prevention

GovernmentBeijing, China
About: Chinese Center for Disease Control and Prevention is a government organization based out in Beijing, China. It is known for research contribution in the topics: Population & Acquired immunodeficiency syndrome (AIDS). The organization has 16037 authors who have published 15098 publications receiving 423452 citations. The organization is also known as: China CDC & CCDC.


Papers
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Journal ArticleDOI
TL;DR: This A/H1N1 epidemic has not caused public panic yet, but the knowledge of A/ H1n1 in residents is not optimistic, and public education campaign may take the side effects of vaccine and the knowledge about the state's vaccination strategy into account.
Abstract: China is at greatest risk of the Pandemic (H1N1) 2009 due to its huge population and high residential density. The unclear comprehension and negative attitudes towards the emerging infectious disease among general population may lead to unnecessary worry and even panic. The objective of this study was to investigate the Chinese public response to H1N1 pandemic and provide baseline data to develop public education campaigns in response to future outbreaks. A close-ended questionnaire developed by the Chinese Center for Disease Control and Prevention was applied to assess the knowledge, attitudes and practices (KAP) of pandemic (H1N1) 2009 among 10,669 responders recruited from seven urban and two rural areas of China sampled by using the probability proportional to size (PPS) method. 30.0% respondents were not clear whether food spread H1N1 virusand. 65.7% reported that the pandemic had no impact on their life. The immunization rates of the seasonal flu and H1N1vaccine were 7.5% and 10.8%, respectively. Farmers and those with lower education level were less likely to know the main transmission route (cough or talk face to face). Female and those with college and above education had higher perception of risk and more compliance with preventive behaviors. Relationships between knowledge and risk perception (OR = 1.69; 95%CI 1.54-1.86), and knowledge and practices (OR = 1.57; 95%CI 1.42-1.73) were found among the study subjects. With regard to the behavior of taking up A/H1N1 vaccination, there are several related factors found in the current study population, including the perception of life disturbed (OR = 1.29; 95%CI 1.11-1.50), the safety of A/H1N1 vaccine (OR = 0.07; 95%CI 0.04-0.11), the knowledge of free vaccination policy (OR = 7.20; 95%CI 5.91-8.78), the state's priority vaccination strategy(OR = 1.33; 95%CI 1.08-1.64), and taking up seasonal influenza vaccine behavior (OR = 4.69; 95%CI 3.53-6.23). This A/H1N1 epidemic has not caused public panic yet, but the knowledge of A/H1N1 in residents is not optimistic. Public education campaign may take the side effects of vaccine and the knowledge about the state's vaccination strategy into account.

117 citations

Journal ArticleDOI
21 Feb 2013-PLOS ONE
TL;DR: The findings showed a strong association between HFMD and meteorological factors, which may assist in predicting HFMD incidence and children years old were more susceptible to HFMD.
Abstract: Objective Hand, foot, and mouth disease (HFMD) has posed a great threat to the health of children and become a public health priority in China. This study aims to investigate the epidemiological characteristics, spatial-temporal patterns, and risk factors of HFMD in Guangdong Province, China, and to provide scientific information for public health responses and interventions. Methods HFMD surveillance data from May 2008 to December 2011were provided by the Chinese Center for Disease Control and Prevention. We firstly conducted a descriptive analysis to evaluate the epidemic characteristics of HFMD. Then, Kulldorff scan statistic based on a discrete Poisson model was used to detect spatial-temporal clusters. Finally, a spatial paneled model was applied to identify the risk factors. Results A total of 641,318 HFMD cases were reported in Guangdong Province during the study period (total population incidence: 17.51 per 10,000). Male incidence was higher than female incidence for all age groups, and approximately 90% of the cases were children years old. Spatial-temporal cluster analysis detected four most likely clusters and several secondary clusters (P<0.001) with the maximum cluster size 50% and 20% respectively during 2008–2011. Monthly average temperature, relative humidity, the proportion of population years, male-to-female ratio, and total sunshine were demonstrated to be the risk factors for HFMD. Conclusion Children years old, especially boys, were more susceptible to HFMD and we should take care of their vulnerability. Provincial capital city Guangzhou and the Pearl River Delta regions had always been the spatial-temporal clusters and future public health planning and resource allocation should be focused on these areas. Furthermore, our findings showed a strong association between HFMD and meteorological factors, which may assist in predicting HFMD incidence.

117 citations

Journal ArticleDOI
TL;DR: Ngb overexpression reduced superoxide anion generation after H/R, whereas glutathione levels were significantly improved compared with WT controls, suggesting that Ngb is neuroprotective against hypoxia, in part by improving mitochondria function and decreasing oxidative stress.
Abstract: Neuroglobin (Ngb) is a recently discovered tissue globin with a high affinity for oxygen that is widely and specifically expressed in neurons of vertebrate central and peripheral nervous systems. Our laboratory and others have showed Ngb over-expression can protect neurons against hypoxic/ischemic insults, but the underlying mechanisms remain poorly understood. In this study, we examined the effects of Ngb over-expression on mitochondrial function, oxidative stress and neurotoxicity in primary cortical neurons following hypoxia/reoxygenation (H/R). Ngb over-expressing transgenic neurons (Ngb-Tg) were significantly protected against H/R-induced cell death. Rates of decline in ATP levels, MTT reduction and mitochondrial membrane potential were significantly ameliorated in Ngb-Tg neurons. Furthermore, Ngb overexpression reduced superoxide anion generation after H/R, whereas glutathione levels were significantly improved compared to WT controls. Taken together, these data suggest that Ngb is neuroprotective against hypoxia, in part by improving mitochondria function and decreasing oxidative stress.

117 citations

Journal ArticleDOI
TL;DR: In this paper, LaCoO3/Al2O3 (LCA) was utilized as a heterogeneous catalyst to activate peroxymonosulfate (PMS) to degrade atrazine (ATZ).

117 citations

Journal ArticleDOI
TL;DR: Excessive drinking, frequent drinking and binge drinking behaviour have reached epidemic proportions among current drinkers in China, and culturally appropriate public health strategies to reduce hazardous drinking behaviour are needed.
Abstract: Aim To obtain information on drinking behaviour and to examine the associations between frequency of drinking, usual daily drinking quantity and binge drinking behaviour among Chinese residents aged 15-69 years. Design A multi-stage clustering sampling method was used to select a nationally representative sample and data were collected as part of the China Chronic Disease and Risk Factor Surveillance by face-to-face interview. Setting Respondents were selected randomly from 160 counties/districts scattered over 31 provinces/autonomous regions/municipalities between August and October, 2007. Participants Weighted analyses included 49 527 Chinese residents (aged 15-69 years). Measurements Prevalence of current drinking and usual daily quantity, median number of annual binge drinking episodes, proportions of excessive drinking, frequent drinking and binge drinking among current drinkers were the main measurements. Results The prevalence of male, female and total current drinking was 55.6%, 15.0% and 35.7%, respectively. On average, male drinkers consumed 47.8 g alcohol per drinking day, whereas females consumed 19.1 g. The median numbers of annual binge drinking episodes were 5.6 for male drinkers and 2.4 for females. Among the current drinkers, proportions of excessive drinking, frequent dinking and binge drinking were 62.7%, 26.3%, 57.3% for men and 51.0%, 7.8%, 26.6% for women, respectively. Logistic regressions showed that binge drinking was associated strongly with drinking frequency and drinking quantity increased with drinking frequency for both genders. Conclusions Excessive drinking, frequent drinking and binge drinking behaviour have reached epidemic proportions among current drinkers in China, and culturally appropriate public health strategies to reduce hazardous drinking behaviour are needed. Language: en

117 citations


Authors

Showing all 16076 results

NameH-indexPapersCitations
Richard Peto183683231434
Barry M. Popkin15775190453
Jian Yang1421818111166
Edward C. Holmes13882485748
Jian Li133286387131
Shaobin Wang12687252463
Elaine Holmes11956058975
Jian Liu117209073156
Sherif R. Zaki10741740081
Jun Yang107209055257
Nan Lin10568754545
Li Chen105173255996
Ming Li103166962672
George F. Gao10279382219
Tao Li102248360947
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202283
20211,490
20201,678
20191,244
20181,041