Institution
Chinese Center for Disease Control and Prevention
Government•Beijing, China•
About: Chinese Center for Disease Control and Prevention is a government organization based out in Beijing, China. It is known for research contribution in the topics: Population & Acquired immunodeficiency syndrome (AIDS). The organization has 16037 authors who have published 15098 publications receiving 423452 citations. The organization is also known as: China CDC & CCDC.
Topics: Population, Acquired immunodeficiency syndrome (AIDS), Virus, Vaccination, Men who have sex with men
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors used Fe3O4 magnetic nanoparticles (MNP) as a nano-probe to detect the glycoprotein of Ebola virus (EBOV) as low as 1 ng/mL, which is 100 times more sensitive than the standard strip method.
279 citations
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National Institutes of Health1, National Health Research Institutes2, Seoul National University3, National University of Singapore4, Yeshiva University5, Tianjin Medical University6, Fudan University7, University of Hong Kong8, Vanderbilt University9, Kyungpook National University10, Academia Sinica11, Korea University12, Nanjing Medical University13, Westat14, Kindai University15, Chonnam National University16, National Yang-Ming University17, Yale University18, China Medical University (PRC)19, Peking Union Medical College20, Anhui Medical University21, Agency for Science, Technology and Research22, Chang Gung University23, Huazhong University of Science and Technology24, Memorial Sloan Kettering Cancer Center25, National Taiwan University26, Chinese Center for Disease Control and Prevention27, Kaohsiung Medical University28, National Cheng Kung University29, National Cancer Research Institute30, China Medical University (Taiwan)31, Utrecht University32, Memorial Hospital of South Bend33
TL;DR: It is observed that there is no evidence of association for lung cancer at 15q25 in never-smoking women in Asia, providing strong evidence that this locus is not associated with lung cancer independent of smoking.
Abstract: To identify common genetic variants that contribute to lung cancer susceptibility, we conducted a multistage genome-wide association study of lung cancer in Asian women who never smoked. We scanned 5,510 never-smoking female lung cancer cases and 4,544 controls drawn from 14 studies from mainland China, South Korea, Japan, Singapore, Taiwan and Hong Kong. We genotyped the most promising variants (associated at P < 5 × 10(-6)) in an additional 1,099 cases and 2,913 controls. We identified three new susceptibility loci at 10q25.2 (rs7086803, P = 3.54 × 10(-18)), 6q22.2 (rs9387478, P = 4.14 × 10(-10)) and 6p21.32 (rs2395185, P = 9.51 × 10(-9)). We also confirmed associations reported for loci at 5p15.33 and 3q28 and a recently reported finding at 17q24.3. We observed no evidence of association for lung cancer at 15q25 in never-smoking women in Asia, providing strong evidence that this locus is not associated with lung cancer independent of smoking.
279 citations
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TL;DR: A ferret model was used to evaluate the infectivity and transmissibility of A/Shanghai/2/2013 (SH2), a human H7N9 virus isolate, which showed limited capacity for airborne infectivity but efficiently transmitted between ferrets via direct contact, but less efficiently by airborne exposure.
Abstract: The emergence of the H7N9 influenza virus in humans in Eastern China has raised concerns that a new influenza pandemic could occur. Here, we used a ferret model to evaluate the infectivity and transmissibility of A/Shanghai/2/2013 (SH2), a human H7N9 virus isolate. This virus replicated in the upper and lower respiratory tracts of the ferrets and was shed at high titers for 6 to 7 days, with ferrets showing relatively mild clinical signs. SH2 was efficiently transmitted between ferrets via direct contact, but less efficiently by airborne exposure. Pigs were productively infected by SH2 and shed virus for 6 days but were unable to transmit the virus to naive pigs or ferrets. Under appropriate conditions, human-to-human transmission of the H7N9 virus may be possible.
278 citations
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TL;DR: Lifestyle intervention in people with impaired glucose tolerance delayed the onset of type 2 diabetes and reduced the incidence of cardiovascular events, microvascular complications, and cardiovascular and all-cause mortality, and increased life expectancy.
278 citations
01 Jan 2011
TL;DR: This review focuses on the development of HLA-B*5701 genetic screening as a means of preventing drug hypersensitivity reactions and the international current research situation.
Abstract: Abacavir hypersensitivity reactions(ABC HSR) is a multi-organ hypersensitivity syndrome caused by abacavir which has been prescribed for the treatment of HIV infection in the West.In 2001 a strong predictive association of carriage of HLA-B*5701 allele with abacavir hypersensitivity reactions was described.Afterwards,a large number of studies were designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to abacavir.This review focuses on the development of HLA-B*5701 genetic screening as a means of preventing drug hypersensitivity reactions and the international current research situation.
275 citations
Authors
Showing all 16076 results
Name | H-index | Papers | Citations |
---|---|---|---|
Richard Peto | 183 | 683 | 231434 |
Barry M. Popkin | 157 | 751 | 90453 |
Jian Yang | 142 | 1818 | 111166 |
Edward C. Holmes | 138 | 824 | 85748 |
Jian Li | 133 | 2863 | 87131 |
Shaobin Wang | 126 | 872 | 52463 |
Elaine Holmes | 119 | 560 | 58975 |
Jian Liu | 117 | 2090 | 73156 |
Sherif R. Zaki | 107 | 417 | 40081 |
Jun Yang | 107 | 2090 | 55257 |
Nan Lin | 105 | 687 | 54545 |
Li Chen | 105 | 1732 | 55996 |
Ming Li | 103 | 1669 | 62672 |
George F. Gao | 102 | 793 | 82219 |
Tao Li | 102 | 2483 | 60947 |