Institution
Chonbuk National University
Education•Jeonju, South Korea•
About: Chonbuk National University is a education organization based out in Jeonju, South Korea. It is known for research contribution in the topics: Apoptosis & Graphene. The organization has 14820 authors who have published 28884 publications receiving 554131 citations.
Topics: Apoptosis, Graphene, Nanofiber, Population, Electrospinning
Papers published on a yearly basis
Papers
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TL;DR: In this article, a simple, rapid and high-yield synthesis of Ce-doped ZnO nanoparticles using solution combustion method and its application for photocatalytic degradation was reported.
137 citations
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TL;DR: The ompX and ompA deletion mutants showed significantly reduced invasion of human enterocyte-like epithelial Caco-2 and human intestinal epithelial INT-407 cells, and significantly fewer mutant cells were recovered from the livers and spleens of rat pups, suggesting that OmpX & A are involved in basolateral invasion by C. sakazakii.
Abstract: Cronobacter sakazakii is an opportunistic pathogen that actively invades host eukaryotic cells. To identify invasion factors responsible for the intestinal translocation of C. sakazakii, we constructed for the first time outer membrane protein X (OmpX) and A (OmpA) deletion mutants using the lambda Red recombination system. The ompX and ompA deletion mutants showed significantly reduced invasion of human enterocyte-like epithelial Caco-2 and human intestinal epithelial INT-407 cells, and significantly fewer mutant cells were recovered from the livers and spleens of rat pups. Furthermore, compared with intact target cells, the invasion and initial association potentials of the mutants increased at a rate similar to that of the wild type in tight-junction-disrupted target cells, suggesting that OmpX and OmpA are involved in basolateral invasion by C. sakazakii. This is the first report of C. sakazakii virulence determinants that are essential for basolateral invasion and that may be critical for the virulence of C. sakazakii.
137 citations
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TL;DR: In this article, the morphology of ZnO materials could be controlled by changing the capping agent at constant alkali solution in hydrothermal process, which resulted in significantly improved PV performance with the overall conversion efficiency.
137 citations
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TL;DR: Evidence is provided that TERT is inducible in postmitotic neurons after ischemic brain injury and prevents NMDA neurotoxicity through shift of the cytosolic free Ca2+ into the mitochondria, and thus plays a protective role in ameliorating isChemic neuronal cell death.
Abstract: The catalytic subunit of telomerase reverse transcriptase (TERT) protects dividing cells from replicative senescence in vitro. Here, we show that expression of TERT mRNA is induced in the ipsilateral cortical neurons after occlusion of the middle cerebral artery in adult mice. Transgenic mice that overexpress TERT showed significant resistance to ischemic brain injury. Among excitotoxicity, oxidative stress, and apoptosis comprising of routes of ischemic neuronal death, NMDA receptor-mediated excitotoxicity was reduced in forebrain cell cultures overexpressing TERT. NMDA-induced accumulation of cytosolic free Ca2+ ([Ca2+]c) was reduced in forebrain neurons from TERT transgenic mice, which was attributable to the rapid flow of [Ca2+]c into the mitochondria from the cytosol without change in Ca2+ influx and efflux through the plasma membrane. The present study provides evidence that TERT is inducible in postmitotic neurons after ischemic brain injury and prevents NMDA neurotoxicity through shift of the cytosolic free Ca2+ into the mitochondria, and thus plays a protective role in ameliorating ischemic neuronal cell death.
137 citations
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TL;DR: Food consumption, efficiency of conversion of ingested and digested food, relative growth rate, and consumption index values declined significantly, but at the same time an increase in approximate digestibility was also observed.
137 citations
Authors
Showing all 14943 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hyun-Chul Kim | 176 | 4076 | 183227 |
Andrew Ivanov | 142 | 1812 | 97390 |
Dong-Chul Son | 138 | 1370 | 98686 |
C. Haber | 135 | 1507 | 98014 |
Tae Jeong Kim | 132 | 1420 | 93959 |
Alessandro Cerri | 129 | 1244 | 103225 |
Paul M. Vanhoutte | 127 | 868 | 62177 |
Jason Nielsen | 125 | 893 | 72688 |
Chi Lin | 125 | 1313 | 102710 |
Paul Lujan | 123 | 1255 | 76799 |
Young Hee Lee | 122 | 1168 | 61107 |
Min Suk Kim | 119 | 975 | 66214 |
Alexandre Sakharov | 119 | 582 | 56771 |
Yang-Kook Sun | 117 | 781 | 58912 |
Rui L. Reis | 115 | 1608 | 63223 |