Chonbuk National University

About: Chonbuk National University is a education organization based out in Jeonju, South Korea. It is known for research contribution in the topics: Apoptosis & Nanofiber. The organization has 14820 authors who have published 28884 publications receiving 554131 citations.

Antimicrobial synergistic effect of linolenic acid and monoglyceride against Bacillus cereus and Staphylococcus aureus.

Abstract: The antimicrobial effect of linolenic acid with or without monoglyceride (glycerol laurate or glycerol myristate) against six food-borne microorganisms was determined in broth medium. Minimum inhibitory concentration of linolenic acid on Bacillus cereus and Staphylococcus aureus was 20 and 50 ppm, respectively. The growth of B. cereus treated with linolenic acid at 10 ppm with 10 ppm monoglyceride was more inhibitory than that of linolenic acid alone, and the viable cell population was reduced 2-4 log cycles compared to that of the control. When linolenic acid was added at that level, the adenosine triphosphate (ATP) concentration of extracellular fluid was drastically increased compared with that of the control, and the combined effect with monoglyceride was higher than that with linolenic acid alone. However, the intracellular ATP concentration decreased compared with that of the control. From these results, we concluded that linolenic acid has a strong antimicrobial activity against B. cereus and S. aureus, and that linolenic acid combined with monoglyceride showed stronger antimicrobial activity than using linolenic acid alone.

Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy.

Abstract: Pericytes are distinctive regulators of angiogenesis and are adumbrated to provide vessel stability and control of endothelial proliferation. The present article spotlights the persona of pericytes in physiological angiogenesis, recruitment of pericytes and different mechanisms of pericyte depletion. Developing retina appears particularly dependent on pericytes, and pericyte loss is considered as hallmark of early diabetic retinopathies. Several factors are contemplated to be engaged in pericyte conscription including angiopoietin-1 and its receptor tyrosine kinase Tie-2, vascular endothelial growth factor-A and its receptor flk-1 and the platelet-derived growth factor PDGF-B/PDGF-beta system. At present, the mechanisms by which diabetes persuade apoptosis in the retinal microvasculature remain indecisive, albeit oxidative stress, formation of advanced glycation end products , upregulation of protein kinase C, increased polyol pathway flux and focal leukostasis may be important. In this context, accelerated microvascular cell death may become a constructive surrogate end-point in pharmacological studies of experimental diabetic.

Reduced graphene oxide (RGO)-supported NiCo₂O₄ nanoparticles: an electrocatalyst for methanol oxidation.

Abstract: The design and development of cheap, highly active, and durable non-platinum (Pt)-based electrocatalysts for methanol electrooxidation is highly desirable, but is a challenging task. In this paper, we demonstrate the application of a hydrothermally synthesized NiCo2O4–reduced graphene oxide (RGO) composite as an electrocatalyst for the electrochemical oxidation of methanol in alkaline pH. The physicochemical properties of the NiCo2O4–RGO composite were investigated via Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Raman spectroscopy (RS), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) measurements. The physical characterization methods confirm the deposition of NiCo2O4 nanoparticles on the RGO surface. The TEM image shows that the NiCo2O4 nanoparticles with an average size of ∼10 nm are distributed over the RGO surface. Compared to RGO and NiCo2O4 nanoparticles, the NiCo2O4–RGO-based electrode shows excellent electrocatalytic activity for the oxidation of methanol in alkaline pH. On the NiCo2O4–RGO-based electrode, the oxidation of methanol occurs at ∼0.6 V with a higher catalytic current density, and the response is highly stable. The excellent electrocatalytic activity of the NiCo2O4–RGO composite is attributed to the synergistic effects between the NiCo2O4 nanoparticles and RGO. Since the NiCo2O4–RGO composite shows a highly stable response during methanol oxidation reaction, it is a very promising material to be used as an electrocatalyst in the development of high performance non-Pt based alkaline fuel cells.

One-step synthesis of robust nitrogen-doped carbon dots: acid-evoked fluorescence enhancement and their application in Fe3+ detection

Abstract: Robust and highly fluorescent N-doped carbon dots (CDs) are obtained from a hybrid source, alginic acid and ethanediamine. During a hydrothermal process, the raw materials are propelled to form nano-sized particles; these resultant CDs possess desirable functional groups on the particle surface. We have further investigated their optical performance under various pH conditions as well as their capacity for sensing metal ions. The N-doped CDs especially exhibit remarkable acid-evoked fluorescence enhancement under acidic conditions. Finally, the as-prepared CDs are tested for their ability to detect Fe3+ in acidic pure water and urban river water media, and the fluorescence-quenching mechanism and recovery properties of the CD/Fe3+ mixture are also investigated.

Medical image fusion via an effective wavelet-based approach

Abstract: A novel wavelet-based approach for medical image fusion is presented, which is developed by taking into not only account the characteristics of human visual system (HVS) but also the physical meaning of the wavelet coefficients. After the medical images to be fused are decomposed by the wavelet transform, different-fusion schemes for combining the coefficients are proposed: coefficients in low-frequency band are selected with a visibility-based scheme, and coefficients in high-frequency bands are selected with a variance based method. To overcome the presence of noise and guarantee the homogeneity of the fused image, all the coefficients are subsequently performed by a window-based consistency verification process. The fused image is finally constructed by the inverse wavelet transform with all composite coefficients. To quantitatively evaluate and prove the performance of the proposed method, series of experiments and comparisons with some existing fusion methods are carried out in the paper. Experimental results on simulated and real medical images indicate that the proposed method is effective and can get satisfactory fusion results.