Showing papers by "CHU Ambroise Paré published in 2020"
TL;DR: This nationwide registry of Sarcoma patients with histology reviewed by sarcoma experts shows that the incidence of sarcomas and TIM is higher than reported, and that tumors with an incidence<106/year have a much lower access to clinical trials.
Abstract: Background Since 2010, NETSARC and RREPS collected and reviewed prospectively all cases of sarcomas and tumors of intermediate malignancy (TIM) nationwide Methods The nationwide incidence of sarcoma or TIM (2013-2016), confirmed by expert pathologists using WHO classification are presented Yearly variations and correlation with published clinical trials was analyzed Results 139 histological subtypes are reported among the 25172 patients with sarcomas (n=18710, 64%) or TIM (n=6460, 36%), respectively n=5838, n=6153, n=6654, and n=6527 yearly from 2013 to 2016 Over these 4 years, the yearly incidence of sarcomas and TIM was therefore 797, 249 and 951/106/year, above that previously reported GIST, liposarcoma, leiomyosarcomas, undifferentiated sarcomas represented 13%, 13%, 11% and 11% of tumors Only GIST, as a single entity had a yearly incidence above 10/million/year There were respectively 30, 63 and 66 different histological subtypes of sarcomas or TIM with an incidence ranging from 10 to 1/106, 1-01/106, or Conclusions This nationwide registry of sarcoma patients with histology reviewed by sarcoma experts shows that the incidence of sarcoma and TIM is higher than reported, and that tumors with an incidence
71 citations
University of California, Los Angeles1, University of Massachusetts Medical School2, Michigan State University3, University of Washington4, University of Colorado Denver5, Johns Hopkins University6, Stanford University7, Loyola University Chicago8, Icahn School of Medicine at Mount Sinai9, Rutgers University10, University of Hamburg11, University of Messina12, University of Texas Health Science Center at Houston13, Louisiana State University14, Northwestern University15, Kyung Hee University16, Harvard University17, CHU Ambroise Paré18, Cornell University19, Hofstra University20, University of British Columbia21, Indiana University22, University of Utah23, National Autonomous University of Mexico24, University of Texas Health Science Center at San Antonio25, Columbia University26, Wayne State University27, University of Auckland28, Yeshiva University29, University of Zurich30, NorthShore University HealthSystem31, Virginia Commonwealth University32, University of California, San Francisco33, Post Graduate Institute of Medical Education and Research34, University of Iowa35, Boston University36, Mayo Clinic37, University of Arizona38, Saint Louis University39
TL;DR: In this article, the authors conducted a cross-sectional, self-reported study of central venous access line teams in hospitals afflicted with the COVID-19 pandemic and found that the line cart was used by 35 (59%) of the hospitals.
15 citations
TL;DR: The need for training programmes of physicians involved in digestive oncology on nutrition and adapted physical activity and their desire for more effective training on these two topics is evaluated.
Abstract: Objectives Sarcopenia, present in more than 50% of digestive oncology patients, has a negative impact on clinical outcomes. Nutrition and adapted physical activity are two major interventions for the management of sarcopenia. However, young hepato-gastroenterologists, oncologists and surgeons in France have limited awareness on these topics. We aimed to evaluate the need for training programmes of physicians (residents and senior doctors) involved in digestive oncology on nutrition and adapted physical activity. Methods A 42-question survey was developed, by a working group of clinicians, dieticians and adapted physical activity teachers, to assess five areas related to demographics of respondents, nutrition practices, nutrition training, adapted physical activity practices and adapted physical activity training. The national survey was undertaken between April and July of 2019. Results 230 physicians participated in the survey; 34% were hepato-gastroenterologists, 31% were oncologists, 23% were surgeons and 40% were residents. Sixty-one per cent of participants had received training in nutrition and only 21% in adapted physical activity. Ninety per cent of the physicians expressed their desire for more effective training on these two topics. Disparities in clinical practices were observed between hepato-gastroenterologists, oncologists and surgeons. Conclusions More initial and continuing training on nutrition and adapted physical activity is needed for French physicians in the current digestive oncology clinical practice.
10 citations
TL;DR: Strategy of serial RT-PCR test must be rigorously evaluated before adoption by clinicians, and patients suspected of COVID19 with higher inflammatory biological findings expected higher risk of false negative CO VID19 RT- PCR test.
Abstract: Background:
Since December 2019, Coronavirus 2019 (Covid-19) emerged in Wuhan city in China, and rapidly spread throughout China, Asia and worldwide. Recently, concerns emerged about specificity of PCR testing especially sensibility. We hypothesis first that clinical and/or biological and/or radiological characteristics of patients with first false negative COVID19 RT-PCR test despite final diagnosis of COVID-19 are different from patients with first positive COVID19 RT-PCR test.
Methods:
Case / control study in which patients with first negative COVID19 RT-PCR test were matched to patients with first positive COVID-19 RT-PCR test on age, gender and ward/ICU location at time of RT-PCR test.
Results:
Between March 30, and June 22, 2020, 82 cases and 80 controls were included. Neither proportion of death at hospital discharge, nor duration of hospital length stay differed between patients Cases and Controls (respectively P=0.53 and P=0.79). In multivariable analysis, fatigue and/or malaise (aOR: 0.16 [0.03 ; 0.81]; P=0.0266), headache (aOR: 0.07
[0.01 ; 0.49]; P=0.0066) were associated with lower risk of false negative whereas platelets upper than 207 per 10.3.mm-3 (aOR: 3.81 [1.10 ; 13.16]; P=0.0344), and CRP>79.8 mg.L-1 (aOR: 4.00 [1.21 ; 13.19]; P=0.0226) were associated with higher risk of false negative.
Interpretation:
Patients suspected of COVID19 with higher inflammatory biological findings expected higher risk of false negative COVID19 RT-PCR test. Strategy of serial RT-PCR test must be rigorously evaluated before adoption by clinicians.
2 citations