Chung-Ang University

About: Chung-Ang University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Thin film. The organization has 13381 authors who have published 26978 publications receiving 416735 citations. The organization is also known as: CAU & Chung.

Fuzzy adaptive turbulent particle swarm optimization

Abstract: In this paper, we introduce turbulence in the particle swarm optimization (TPSO) and illustrate how this approach could be used for function optimization problems involving high dimensions. The proposed algorithm uses a minimum velocity threshold to control the velocity of particles. TPSO mechanism is similar to a turbulent pump, which supplies some power to the swarm system to explore new search spaces (better solutions). The minimum velocity threshold of the particles is tuned adoptively by using a fuzzy logic controller, which is further called as fuzzy adaptive TPSO (FATPSO). We evaluate and compare the performance of SPSO (Standard PSO), TPSO and FATPSO. Empirical results clearly demonstrate that the performance of SPSO degrades remarkably with the increase in the dimensions of the problem, while the influence is very little in the case of TPSO and FATPSO.

Amniotic membrane transplantation in infectious corneal ulcer.

Abstract: Purpose.To evaluate the efficacy of amniotic membrane transplantation in the management of treated infectious corneal ulcer in which inflammatory reactions were responsible for corneal damage.Method.A prospective study of 21 consecutive eyes (21 patients) was performed. Sufficient antibacterial, ant

Ocular Surface Discomfort and Demodex: Effect of Tea Tree Oil Eyelid Scrub in Demodex Blepharitis

Abstract: The purpose of this study was to evaluate the relation between ocular discomfort and ocular Demodex infestation, and therapeutic effects of tea tree oil (TTO) in Demodex blepharitis patients. Three hundred and thirty-five patients with ocular discomfort were evaluated for ocular Demodex infestation and subjective symptoms with ocular surface discomfort index (OSDI) score. Among them, Demodex-infested patients were randomized to receive either eyelid scrubbing with TTO (TTO group,106 patients) or without TTO (Control group, 54 patients) for 1 month. Demodex were found in 84% of patients with ocular discomfort. The number of Demodex was significantly correlated with age (P = 0.04) and OSDI score (P = 0.024). After eyelid scrub treatment, Demodex count was reduced from 4.0 ± 2.5 to 3.2 ± 2.3 in the TTO group (P = 0.004) and from 4.3 ± 2.7 to 4.2 ± 2.5 in the control group (P = 0.27). Also, OSDI score was reduced from 34.5 ± 10.7 to 24.1 ± 11.9 in the TTO group (P = 0.001) and from 35.3 ± 11.6 to 27.5 ± 12.8 in the control group (P = 0.04). In conclusion, Demodex number showed a significant positive correlation with age and subjective ocular discomfort. The tea tree oil eyelid scrub treatment is effective for eliminating ocular Demodex and improving subjective ocular symptoms.

Routing in Flying Ad Hoc Networks: A Comprehensive Survey

Abstract: The use of unmanned aerial vehicles (UAVs) is attracting considerable interest in academic research, commercial, and military applications. Multi-UAV systems organized in an ad hoc fashion called a flying ad hoc network (FANET) can cooperatively and collaboratively accomplish complex missions more efficiently compared to single large UAV systems. However, the unique features of FANETs such as high mobility, low node density, and high frequency of topology changes introduce challenges to the communication design, especially routing. Thus, the routing requirements of FANETs surpass those of MANETs or VANETs. In this paper, we present UAV classification, communication and application architectures, and an exhaustive survey of the existing routing protocols for flying ad hoc networks. Furthermore, we highlight the key features, strengths and weaknesses, and different mobility models used for the performance evaluation of the existing FANET routing protocols. More importantly, a proposed taxonomy and a review on the existing FANET routing protocols are presented. Finally, we highlight the existing challenges and open research issues.

Reduction of Hypoxia-Induced Transcription through the Repression of Hypoxia-Inducible Factor-1α/Aryl Hydrocarbon Receptor Nuclear Translocator DNA Binding by the 90-kDa Heat-Shock Protein Inhibitor Radicicol

Abstract: Under low oxygen tension, cells increase the transcription of specific genes involved in angiogenesis, erythropoiesis, and glycolysis. Hypoxia-induced gene expression depends primarily on stabilization of the alpha subunit of hypoxia-inducible factor-1 (HIF-1alpha), which acts as a heterodimeric trans-activator with the nuclear protein known as the aryl hydrocarbon receptor nuclear translocator (Arnt). The resulting heterodimer (HIF-1alpha/Arnt) interacts specifically with the hypoxia-responsive element (HRE), thereby increasing transcription of the genes under HRE control. Our results indicate that the 90-kDa heat-shock protein (Hsp90) inhibitor radicicol reduces the hypoxia-induced expression of both endogenous vascular endothelial growth factor (VEGF) and HRE-driven reporter plasmids. Radicicol treatment (0.5 microg/ml) does not significantly change the stability of the HIF-1alpha protein and does not inhibit the nuclear localization of HIF-1alpha. However, this dose of radicicol significantly reduces HRE binding by the HIF-1alpha/Arnt heterodimer. Our results, the first to show that radicicol specifically inhibits the interaction between the HIF-1alpha/Arnt heterodimer and HRE, suggest that Hsp90 modulates the conformation of the HIF-1alpha/Arnt heterodimer, making it suitable for interaction with HRE. Furthermore, we demonstrate that radicicol reduces hypoxia-induced VEGF expression to decrease hypoxia-induced angiogenesis.