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Institution

Chung Yuan Christian University

EducationTaoyuan City, Taiwan
About: Chung Yuan Christian University is a education organization based out in Taoyuan City, Taiwan. It is known for research contribution in the topics: Membrane & Fuzzy logic. The organization has 9819 authors who have published 11623 publications receiving 213139 citations. The organization is also known as: Tiong-gôan-tāi-ha̍k & CYCU.


Papers
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Journal ArticleDOI
TL;DR: The optimized PSBMA surface graft layer in overall charge neutrality has a high hydration capability and the best antifouling, anticoagulant, and antihemolytic activities when comes into contact with human blood.
Abstract: Development of nonfouling membranes to prevent nonspecific protein adsorption and platelet adhesion is critical for many biomedical applications. It is always a challenge to control the surface graft copolymerization of a highly polar monomer from the highly hydrophobic surface of a fluoropolymer membrane. In this work, the blood compatibility of poly(vinylidene fluoride) (PVDF) membranes with surface-grafted electrically neutral zwitterionic poly(sulfobetaine methacrylate) (PSBMA), from atmospheric plasma-induced surface copolymerization, was studied. The effect of surface composition and graft morphology, electrical neutrality, hydrophilicity and hydration capability on blood compatibility of the membranes were determined. Blood compatibility of the zwitterionic PVDF membranes was systematically evaluated by plasma protein adsorption, platelet adhesion, plasma-clotting time, and blood cell hemolysis. It was found that the nonfouling nature and hydration capability of grafted PSBMA polymers can be effectively controlled by regulating the grafting coverage and charge balance of the PSBMA layer on the PVDF membrane surface. Even a slight charge bias in the grafted zwitterionic PSBMA layer can induce electrostatic interactions between proteins and the membrane surfaces, leading to surface protein adsorption, platelet activation, plasma clotting and blood cell hemolysis. Thus, the optimized PSBMA surface graft layer in overall charge neutrality has a high hydration capability and the best antifouling, anticoagulant, and antihemolytic activities when comes into contact with human blood.

291 citations

Journal ArticleDOI
TL;DR: Ethanol extracts showed anti-fungal activities in vitro against dermatophytes such as Trichophyton rubrum, Trichopterton mentagrophytes, Epidermophyton floccosum, and Microsporum canis.

291 citations

Journal ArticleDOI
TL;DR: After maternal age, pre-pregnant BMI, and parity were adjusted, increased PBDEs in breast milk was related with decreased birth outcome, particularly for birth weight and length, chest circumference, and Quetelet's index of infants.

281 citations

Journal ArticleDOI
TL;DR: A nonlinear mathematical model to consider production scheduling and vehicle routing with time windows for perishable food products in the same framework to maximize the expected total profit of the supplier is proposed.

281 citations

Journal ArticleDOI
TL;DR: It is indicated that when shortage is allowed, the model leads to lower average total cost, and a comparison of policies is made.

265 citations


Authors

Showing all 9844 results

NameH-indexPapersCitations
Simon Lin12675469084
Xiaodong Li104130049024
Yu Wang92168747472
Leaf Huang9235025867
Duu-Jong Lee9197937292
Yen Wei8564925805
Ru-Shi Liu8273826699
Kazuhiko Ishihara7771324795
Gwo-Hshiung Tzeng7746526807
Huan-Tsung Chang7640521476
Hari M. Srivastava76112642635
Jianhua Yang7455427839
Yen Wei6830917527
Hsisheng Teng6721314408
Kevin C.-W. Wu6627815193
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202315
202271
2021590
2020633
2019569
2018514