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Institution

Chung Yuan Christian University

EducationTaoyuan City, Taiwan
About: Chung Yuan Christian University is a education organization based out in Taoyuan City, Taiwan. It is known for research contribution in the topics: Membrane & Fuzzy logic. The organization has 9819 authors who have published 11623 publications receiving 213139 citations. The organization is also known as: Tiong-gôan-tāi-ha̍k & CYCU.


Papers
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Journal ArticleDOI
TL;DR: A hybrid algorithm to generate a picking sequence for combining picking and packing operations and includes three elements: container selection, loading configuration, and loading/picking sequence is developed.

64 citations

Journal ArticleDOI
TL;DR: In this article, the structure, surface chemistry and electrochemical behaviors of reduced graphene oxides are investigated by Raman spectroscopy, N2 adsorption, temperature-programmed desorption and Fourier transform infrared spectrograms.

64 citations

Journal ArticleDOI
TL;DR: In this paper, a ball-type balancer system installed on the high-speed disk drive in order to reduce radial vibrations of rotors caused by eccentricities of disk's center of gravity and circular runway of the ball balancer was designed.

64 citations

Journal ArticleDOI
TL;DR: In this article, the authors investigated the hydrogen adsorption and storage capacity on various carbon-based ring materials decorated with alkali metal ions by using quantum chemistry calculations, and they showed that the Li+-, Na+-, and K+decorated carbon based molecular complexes with B-and N-substitution enhance the hydrogen storage capacity.
Abstract: The hydrogen adsorption and storage capacity on various carbon-based ring materials decorated with alkali metal ions have been systematically investigated by using quantum chemistry calculations. To improve the bonding ability between H2 molecules and carbon-ring based molecular complexes, we also explain the strategy of modifying the carbon ring materials by substituting carbon element to boron or nitrogen element (up to three atoms). Our calculations show that the Li+-, Na+-, and K+-decorated carbon-based molecular complexes with B- and N-substitution enhance the hydrogen storage capacity. The Mulliken charge analysis is performed to illustrate the interaction between H2 and M+@carbon-ring complex. The number of binding H2 molecules on the M+-carbon-ring complexes (M+ = Li+, Na+, and K+) depends on ionic radii of the metal cations. It is found that corresponding gravimetric density are predicted to be 11.21–13.95 and 10.42–13.24 wt % for the B- and N-substituted complexes, respectively.

64 citations

Journal ArticleDOI
01 Nov 2018-Allergy
TL;DR: Epithelium‐derived thymic stromal lymphopoietin, interleukin, and IL‐33 are implicated in the dysregulation of Th2 immune responses in severe allergic asthma.
Abstract: BACKGROUND Exposure to environmental pollutants promotes Th2 cell responses. Aryl hydrocarbon receptor (AhR) activation aggravates allergic responses. Epithelium-derived thymic stromal lymphopoietin (TSLP), interleukin (IL)-25, and IL-33 are implicated in the dysregulation of Th2 immune responses in severe allergic asthma. METHODS Bronchial biopsies of 28 allergic severe asthma and 6 mild asthma subjects from highly polluted areas were analyzed for AhR nuclear translocation (NT), cytokine expression, and gene activation. Cultured primary epithelial cells were stimulated with diesel exhausted particles (DEP) to determine AhR-mediated IL-33, Il-25, and TSLP synthesis and release. RESULTS Primary bronchial epithelial cells exposed to DEP showed upregulation of IL-33, IL-25, and TSLP. These effects were abolished by knockdown of AhR by siRNA. Increased AhR/ARNT binding to promoters of IL-33, IL-25, and TSLP was found using chromatin immunoprecipitation (ChIP) assay. Allergic severe asthma with high AhR NT had higher bronchial gene and protein expression of IL-33, IL-25, and TSLP. These patients derived clinical benefit from anti-IgE treatment. CONCLUSION Aryl hydrocarbon receptor activation by DEP mediates upregulation of IL-33, IL-25, and TSLP with Th2 activation, potentially linking environmental pollution and allergic severe asthma.

64 citations


Authors

Showing all 9844 results

NameH-indexPapersCitations
Simon Lin12675469084
Xiaodong Li104130049024
Yu Wang92168747472
Leaf Huang9235025867
Duu-Jong Lee9197937292
Yen Wei8564925805
Ru-Shi Liu8273826699
Kazuhiko Ishihara7771324795
Gwo-Hshiung Tzeng7746526807
Huan-Tsung Chang7640521476
Hari M. Srivastava76112642635
Jianhua Yang7455427839
Yen Wei6830917527
Hsisheng Teng6721314408
Kevin C.-W. Wu6627815193
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202315
202271
2021590
2020633
2019569
2018514