Institution
City University London
Education•London, United Kingdom•
About: City University London is a education organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 5735 authors who have published 17285 publications receiving 453290 citations.
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VU University Amsterdam1, University of Bern2, Harvard University3, University of Oxford4, Public Health Research Institute5, University of Wuppertal6, Kyoto University7, University of Amsterdam8, University of New South Wales9, University of Melbourne10, City University London11, University of Gothenburg12, Free University of Berlin13, University of Texas at Austin14, James I University15, Carlos III Health Institute16, Ohio State University17, Northwestern University18, University of Erlangen-Nuremberg19, University Hospitals Bristol NHS Foundation Trust20, University of Bristol21, Trinity College, Dublin22, University of York23, Karolinska Institutet24, Peking Union Medical College25, Linköping University26, University of Regina27, University of Sydney28, McLean Hospital29, University of Lübeck30, University of Zaragoza31, Imperial College London32, University of Nottingham33, University of Hamburg34, Oregon Research Institute35, Australian National University36, The Ohio State University Wexner Medical Center37, Hofstra University38, Stockholm University39, Hull York Medical School40, Tilburg University41, Linnaeus University42
TL;DR: In this article, the authors conducted a systematic review and IPD network meta-analysis and estimated relative treatment effect sizes across different patient characteristics through IPD-network meta-regression, and found that both guided and unguided iCBT were associated with more effectiveness as measured by PHQ-9 scores than control treatments over the short term and the long term.
Abstract: Importance Personalized treatment choices would increase the effectiveness of internet-based cognitive behavioral therapy (iCBT) for depression to the extent that patients differ in interventions that better suit them. Objective To provide personalized estimates of short-term and long-term relative efficacy of guided and unguided iCBT for depression using patient-level information. Data Sources We searched PubMed, Embase, PsycInfo, and Cochrane Library to identify randomized clinical trials (RCTs) published up to January 1, 2019. Study Selection Eligible RCTs were those comparing guided or unguided iCBT against each other or against any control intervention in individuals with depression. Available individual patient data (IPD) was collected from all eligible studies. Depression symptom severity was assessed after treatment, 6 months, and 12 months after randomization. Data Extraction and Synthesis We conducted a systematic review and IPD network meta-analysis and estimated relative treatment effect sizes across different patient characteristics through IPD network meta-regression. Main Outcomes and Measures Patient Health Questionnaire–9 (PHQ-9) scores. Results Of 42 eligible RCTs, 39 studies comprising 9751 participants with depression contributed IPD to the IPD network meta-analysis, of which 8107 IPD were synthesized. Overall, both guided and unguided iCBT were associated with more effectiveness as measured by PHQ-9 scores than control treatments over the short term and the long term. Guided iCBT was associated with more effectiveness than unguided iCBT (mean difference [MD] in posttreatment PHQ-9 scores, −0.8; 95% CI, −1.4 to −0.2), but we found no evidence of a difference at 6 or 12 months following randomization. Baseline depression was found to be the most important modifier of the relative association for efficacy of guided vs unguided iCBT. Differences between unguided and guided iCBT in people with baseline symptoms of subthreshold depression (PHQ-9 scores 5-9) were small, while guided iCBT was associated with overall better outcomes in patients with baseline PHQ-9 greater than 9. Conclusions and Relevance In this network meta-analysis with IPD, guided iCBT was associated with more effectiveness than unguided iCBT for individuals with depression, benefits were more substantial in individuals with moderate to severe depression. Unguided iCBT was associated with similar effectiveness among individuals with symptoms of mild/subthreshold depression. Personalized treatment selection is entirely possible and necessary to ensure the best allocation of treatment resources for depression.
271 citations
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Abstract: This article takes stock of the discourse on ‘political CSR’ (PCSR), reconsiders some of its assumptions, and suggests new directions for what we call ‘PCSR 2.0’. We start with a definition of PCSR, focusing on firms’ contribution to public goods. We then discuss historical antecedents to the debate and outline the original economic and political context. The following section explores emerging changes in the institutional context relevant to PCSR and reconsiders some of the assumptions underlying Habermas’ thesis of the postnational constellation. This highlights some neglected issues in previous works on PCSR, including the influence of nationalism and fundamentalism, the role of various types of business organisations, the return of government regulation, the complexity of institutional contexts, the efficiency of private governance, the financialization and digitalization of the economy, and the relevance of managerial sensemaking. Finally, we discuss the contributions to this special issue and relate them to the newly emerging research agenda.
271 citations
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TL;DR: All three questionnaires indicated that worriers were characterized by an information-seeking, monitoring cognitive style and a tendency to indulge in avoidance coping behaviours, suggesting the development of a clinically useful diagnostic instrument is needed.
270 citations
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TL;DR: Retention interval was manipulated in two recognition-memory experiments in which subjects indicated when recognizing a word whether its recognition was accompanied by some recollective experience (“remember”) or whether it was recognized on the basis of familiarity without any recollectIVE experience ( “know”).
Abstract: Retention interval was manipulated in two recognition-memory experiments in which subjects indicated when recognizing a word whether its recognition was accompanied by some recollective experience (“remember”) or whether it was recognized on the basis of familiarity without any recollective experience (“know”). Experiment 1 showed that between 10 mm and 1 week, “remember” responses declined sharply from an initially higher level, whereas “know” responses remained relatively unchanged. Experiment 2 showed that between 1 week and 6 months, both kinds of responses declined at a similar, gradual rate and that despite quite low levels of performance after 6 months, both kinds of responses still gave rise to accurate discrimination between target words and lures. These findings are discussed in relationship to current ideas about multiple memory systems and processing accounts of explicit and implicit measures of retention.
269 citations
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TL;DR: The paper is an attempt to explore some of the issues underlying scenario-based approaches in requirements engineering and to propose a framework for their classification, a four-dimensional framework which advocates that a scenario- based approach can be well defined by its form, content, purpose and life cycle.
Abstract: The requirements engineering, information systems and software engineering communities recently advocated scenario-based approaches which emphasise the user/system interaction perspective in developing computer systems. Use of examples, scenes, narrative descriptions of contexts, mock-ups and prototypes-all these ideas can be called scenario-based approaches, although exact definitions are not easy beyond stating that these approaches emphasise some description of the real world. Experience seems to tell us that people react to ‘real things’ and that this helps in clarifying requirements. Indeed, the widespread acceptance of prototyping in system development points to the effectiveness of scenario-based approaches. However, we have little understanding about how scenarios should be constructed, little hard evidence about their effectiveness and even less idea about why they work. The paper is an attempt to explore some of the issues underlying scenario-based approaches in requirements engineering and to propose a framework for their classification. The framework is a four-dimensional framework which advocates that a scenario-based approach can be well defined by itsform, content, purpose andlife cycle. Every dimension is itself multifaceted and a metric is associated with each facet. Motivations for developing the framework are threefold: (a) to help in understanding and clarifying existing scenario-based approaches; (b) to situate the industrial practice of scenarios; and (c) to assist researchers develop more innovative scenario-based approaches.
267 citations
Authors
Showing all 5822 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrew M. Jones | 103 | 764 | 37253 |
F. Rauscher | 100 | 605 | 36066 |
Thorsten Beck | 99 | 373 | 62708 |
Richard J. K. Taylor | 91 | 1543 | 43893 |
Christopher N. Bowman | 90 | 639 | 38457 |
G. David Batty | 88 | 451 | 23826 |
Xin Zhang | 87 | 1714 | 40102 |
Richard J. Cook | 84 | 571 | 28943 |
Hugh Willmott | 82 | 310 | 26758 |
Scott Reeves | 82 | 441 | 27470 |
Sarah-Jayne Blakemore | 81 | 211 | 29660 |
Mats Alvesson | 78 | 267 | 38248 |
W. John Edmunds | 75 | 252 | 24018 |
Sheng Chen | 71 | 688 | 27847 |
Christopher J. Taylor | 71 | 415 | 30948 |