scispace - formally typeset
Search or ask a question
Institution

Clemson University

EducationClemson, South Carolina, United States
About: Clemson University is a education organization based out in Clemson, South Carolina, United States. It is known for research contribution in the topics: Population & Control theory. The organization has 20556 authors who have published 42518 publications receiving 1170779 citations. The organization is also known as: Clemson Agricultural College of South Carolina.


Papers
More filters
Journal ArticleDOI
TL;DR: In this paper, the authors investigate the control framework that results from a lean manufacturing strategic initiative and develop a theoretical framework that assists in understanding the control choices, accounting practices, and organizational structure associated with lean manufacturing.

190 citations

Journal ArticleDOI
TL;DR: The e-ASTROGAM (enhanced ASTROGAM) project as mentioned in this paper is a breakthrough Observatory space mission, with a detector composed by a Silicon tracker, a calorimeter, and an anticoincidence system, dedicated to the study of the non-thermal Universe in the photon energy range from 0.3 MeV to 3 GeV.
Abstract: e-ASTROGAM (‘enhanced ASTROGAM’) is a breakthrough Observatory space mission, with a detector composed by a Silicon tracker, a calorimeter, and an anticoincidence system, dedicated to the study of the non-thermal Universe in the photon energy range from 0.3 MeV to 3 GeV – the lower energy limit can be pushed to energies as low as 150 keV, albeit with rapidly degrading angular resolution, for the tracker, and to 30 keV for calorimetric detection. The mission is based on an advanced space-proven detector technology, with unprecedented sensitivity, angular and energy resolution, combined with polarimetric capability. Thanks to its performance in the MeV-GeV domain, substantially improving its predecessors, e-ASTROGAM will open a new window on the non-thermal Universe, making pioneering observations of the most powerful Galactic and extragalactic sources, elucidating the nature of their relativistic outflows and their effects on the surroundings. With a line sensitivity in the MeV energy range one to two orders of magnitude better than previous generation instruments, e-ASTROGAM will determine the origin of key isotopes fundamental for the understanding of supernova explosion and the chemical evolution of our Galaxy. The mission will provide unique data of significant interest to a broad astronomical community, complementary to powerful observatories such as LIGO-Virgo-GEO600-KAGRA, SKA, ALMA, E-ELT, TMT, LSST, JWST, Athena, CTA, IceCube, KM3NeT, and the promise of eLISA.

190 citations

Journal ArticleDOI
TL;DR: In this article, the authors identify and test key factors that can be associated with time to recall a product and their relationship with recall strategies, source of the defect and supply chain position of the recalling firm.

190 citations

Journal ArticleDOI
TL;DR: The effects of CB2 receptor agonists on TNF‐α‐induced proliferation, migration and signal transduction in human coronary artery smooth muscle cells (HCASMCs) are investigated.
Abstract: Background and purpose: Vascular smooth muscle proliferation and migration triggered by inflammatory stimuli are involved in the development and progression of atherosclerosis and restenosis. Cannabinoids may modulate cell proliferation in various cell types through cannabinoid 2 (CB2) receptors. Here, we investigated the effects of CB2 receptor agonists on TNF-α-induced proliferation, migration and signal transduction in human coronary artery smooth muscle cells (HCASMCs). Experimental approach: HCASMCs were stimulated with TNF-α. Smooth muscle proliferation was determined by the extent of BrdU incorporation and the migration was assayed by modified Boyden chamber. CB2 and/or CB1 receptor expressions were determined by immunofluorescence staining, western blotting, RT-PCR, real-time PCR and flow cytometry. Key results: Low levels of CB2 and CB1 receptors were detectable in HCASMCs compared to the high levels of CB2 receptors expressed in THP-1 monocytes. TNF-α triggered up to ∼80% increase (depending on the method used) in CB2 receptor mRNA and/or protein expression in HCASMCs, and induced Ras, p38 MAPK, ERK 1/2, SAPK/JNK and Akt activation, while increasing proliferation and migration. The CB2 agonists, JWH-133 and HU-308, dose-dependently attenuated these effects of TNF-α. Conclusions and implications: Since the above-mentioned TNF-α-induced phenotypic changes are critical in the initiation and progression of atherosclerosis and restenosis, our findings suggest that CB2 agonists may offer a novel approach in the treatment of these pathologies by decreasing vascular smooth muscle proliferation and migration. British Journal of Pharmacology (2008) 153, 347–357; doi:10.1038/sj.bjp.0707569; published online 12 November 2007

189 citations

Journal ArticleDOI
TL;DR: This article proposes a framework to infuse a unique human-like ability, building and actively repairing trust, into autonomous systems, and proposes a model to guide the design of future autonomy.
Abstract: Modern interactions with technology are increasingly moving away from simple human use of computers as tools to the establishment of human relationships with autonomous entities that carry out acti...

189 citations


Authors

Showing all 20718 results

NameH-indexPapersCitations
Yury Gogotsi171956144520
Philip S. Yu1481914107374
Aaron Dominguez1471968113224
Danny Miller13351271238
Marco Ajello13153558714
David C. Montefiori12992070049
Frank L. Lewis114104560497
Jianqing Fan10448858039
Wei Chen103143844994
Ken A. Dill9940141289
Gerald Schubert9861434505
Rod A. Wing9833347696
Feng Chen95213853881
Jimin George9433162684
François Diederich9384346906
Network Information
Related Institutions (5)
Texas A&M University
164.3K papers, 5.7M citations

97% related

Pennsylvania State University
196.8K papers, 8.3M citations

96% related

University of Illinois at Urbana–Champaign
225.1K papers, 10.1M citations

96% related

Purdue University
163.5K papers, 5.7M citations

96% related

Michigan State University
137K papers, 5.6M citations

96% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202363
2022253
20212,407
20202,362
20192,080
20181,978