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Institution

Clemson University

EducationClemson, South Carolina, United States
About: Clemson University is a education organization based out in Clemson, South Carolina, United States. It is known for research contribution in the topics: Population & Control theory. The organization has 20556 authors who have published 42518 publications receiving 1170779 citations. The organization is also known as: Clemson Agricultural College of South Carolina.


Papers
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Journal ArticleDOI
01 Sep 2011-Mbio
TL;DR: A novel random matrix theory (RMT)-based conceptual framework is described to discern phylogenetic molecular ecological networks of microbial communities based on high-throughput metagenomic sequencing data, among the first to document that the network interactions among different phylogenetic populations in soil microbial communities were substantially changed by a global change such as an elevated CO2 level.
Abstract: Understanding the interactions among different species and their responses to environmental changes, such as ele- vated atmospheric concentrations of CO2, is a central goal in ecology but is poorly understood in microbial ecology. Here we describe a novel random matrix theory (RMT)-based conceptual framework to discern phylogenetic molecular ecological net- works using metagenomic sequencing data of 16S rRNA genes from grassland soil microbial communities, which were sampled from a long-term free-air CO2enrichment experimental facility at the Cedar Creek Ecosystem Science Reserve in Minnesota. Our experimental results demonstrated that an RMT-based network approach is very useful in delineating phylogenetic molecu- lar ecological networks of microbial communities based on high-throughput metagenomic sequencing data. The structure of the identified networks under ambient and elevated CO 2levels was substantially different in terms of overall network topology, net- work composition, node overlap, module preservation, module-based higher-order organization, topological roles of individual nodes, and network hubs, suggesting that the network interactions among different phylogenetic groups/populations were markedly changed. Also, the changes in network structure were significantly correlated with soil carbon and nitrogen contents, indicating the potential importance of network interactions in ecosystem functioning. In addition, based on network topology, microbial populations potentially most important to community structure and ecosystem functioning can be discerned. The novel approach described in this study is important not only for research on biodiversity, microbial ecology, and systems micro- biology but also for microbial community studies in human health, global change, and environmental management. IMPORTANCE The interactions among different microbial populations in a community play critical roles in determining ecosys- tem functioning, but very little is known about the network interactions in a microbial community, owing to the lack of appro- priate experimental data and computational analytic tools. High-throughput metagenomic technologies can rapidly produce a massive amount of data, but one of the greatest difficulties is deciding how to extract, analyze, synthesize, and transform such a vast amount of information into biological knowledge. This study provides a novel conceptual framework to identify microbial interactions and key populations based on high-throughput metagenomic sequencing data. This study is among thefirst to doc- ument that the network interactions among different phylogenetic populations in soil microbial communities were substantially changed by a global change such as an elevated CO2level. The framework developed will allow microbiologists to address re- search questions which could not be approached previously, and hence, it could represent a new direction in microbial ecology research.

708 citations

Journal ArticleDOI
TL;DR: In this paper, a theoretical framework for the Galerkin finite element approximation to the steady state fractional advection dispersion equation is presented, and appropriate fractional derivative spaces are defined and shown to be equivalent to the usual fractional dimension Sobolev spaces Hs.
Abstract: In this article a theoretical framework for the Galerkin finite element approximation to the steady state fractional advection dispersion equation is presented. Appropriate fractional derivative spaces are defined and shown to be equivalent to the usual fractional dimension Sobolev spaces Hs. Existence and uniqueness results are proven, and error estimates for the Galerkin approximation derived. Numerical results are included that confirm the theoretical estimates. © 2005 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2005

707 citations

Journal ArticleDOI
01 Aug 2020-Obesity
TL;DR: The aim of this study was to test the hypothesis that youths with obesity, when removed from structured school activities and confined to their homes during the coronavirus disease 2019 pandemic will display unfavorable trends in lifestyle behaviors.
Abstract: OBJECTIVE: The aim of this study was to test the hypothesis that youths with obesity, when removed from structured school activities and confined to their homes during the coronavirus disease 2019 pandemic, will display unfavorable trends in lifestyle behaviors. METHODS: The sample included 41 children and adolescents with obesity participating in a longitudinal observational study located in Verona, Italy. Lifestyle information including diet, activity, and sleep behaviors was collected at baseline and 3 weeks into the national lockdown during which home confinement was mandatory. Changes in outcomes over the two study time points were evaluated for significance using paired t tests. RESULTS: There were no changes in reported vegetable intake; fruit intake increased (P = 0.055) during the lockdown. By contrast, potato chip, red meat, and sugary drink intakes increased significantly during the lockdown (P value range, 0.005 to < 0.001). Time spent in sports activities decreased by 2.30 (SD 4.60) h/wk (P = 0.003), and sleep time increased by 0.65 (SD 1.29) h/d (P = 0.003). Screen time increased by 4.85 (SD 2.40) h/d (P < 0.001). CONCLUSIONS: Recognizing these adverse collateral effects of the coronavirus disease 2019 pandemic lockdown is critical in avoiding depreciation of weight control efforts among youths afflicted with excess adiposity. Depending on duration, these untoward lockdown effects may have a lasting impact on a child's or adolescent's adult adiposity level.

706 citations

Journal ArticleDOI
TL;DR: In this paper, the authors argue that complexity theory focuses leadership efforts on behaviors that enable organizational effectiveness, as opposed to determining or guiding effectiveness, and develop a definition of organizational complexity and apply it to leadership science, discuss strategies for enabling complexity and effectiveness.
Abstract: This paper asks how complexity theory informs the role of leadership in organizations. Complexity theory is a science of complexly interacting systems; it explores the nature of interaction and adaptation in such systems and how they influence such things as emergence, innovation, and fitness. We argue that complexity theory focuses leadership efforts on behaviors that enable organizational effectiveness, as opposed to determining or guiding effectiveness. Complexity science broadens conceptualizations of leadership from perspectives that are heavily invested in psychology and social psychology (e.g., human relations models) to include processes for managing dynamic systems and interconnectivity. We develop a definition of organizational complexity and apply it to leadership science, discuss strategies for enabling complexity and effectiveness, and delve into the relationship between complexity theory and other currently important leadership theories. The paper concludes with a discussion of possible implications for research strategies in the social sciences.

706 citations

Journal ArticleDOI
TL;DR: The results indicate that commercial inkjet printing technology can be used to create viable cellular patterns with a resolution of 350 microm through the deposition of biologically active proteins.

703 citations


Authors

Showing all 20718 results

NameH-indexPapersCitations
Yury Gogotsi171956144520
Philip S. Yu1481914107374
Aaron Dominguez1471968113224
Danny Miller13351271238
Marco Ajello13153558714
David C. Montefiori12992070049
Frank L. Lewis114104560497
Jianqing Fan10448858039
Wei Chen103143844994
Ken A. Dill9940141289
Gerald Schubert9861434505
Rod A. Wing9833347696
Feng Chen95213853881
Jimin George9433162684
François Diederich9384346906
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202363
2022253
20212,407
20202,362
20192,080
20181,978