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Institution

Clinical Emergency Hospital Bucharest

HealthcareBucharest, Romania
About: Clinical Emergency Hospital Bucharest is a healthcare organization based out in Bucharest, Romania. It is known for research contribution in the topics: Population & Medicine. The organization has 381 authors who have published 276 publications receiving 2188 citations. The organization is also known as: Floreasca Hospital & Spitalul Floreasca.


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Journal Article
TL;DR: In this vision, the POP–Q system may reach the importance and recognition of the TNM system use in oncology, because, although is not very simple as a concept, it helps defining the features of a prolapse at a level of completeness not reached by any other system to date.
Abstract: This paper briefly describes the POP–Q system, by comparison with other staging systems, analyzing its main features and the concept behind it

222 citations

Journal ArticleDOI
TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to natural disasters.
Abstract: [This corrects the article DOI: 10.1186/s13054-016-1208-6.].

180 citations

Journal ArticleDOI
TL;DR: Omadacycline was noninferior to moxifloxacin for the treatment of community‐acquired bacterial pneumonia in adults and investigator‐assessed clinical response at a post‐treatment evaluation 5 to 10 days after the last dose.
Abstract: Background Omadacycline, a new once-daily aminomethylcycline antibiotic agent that can be administered intravenously or orally, reaches high concentrations in pulmonary tissues and is acti...

132 citations

Journal ArticleDOI
TL;DR: Tigecycline appeared safe and achieved cure rates similar to LEV in hospitalized patients with CAP, and microbiologic efficacy and susceptibility to TGC for CAP bacteria were significantly higher in TGC than in LEV.

107 citations

Journal Article
TL;DR: Analyzing cardiac dysfunctions occurring after spinal cord injury (SCI) finds that proper prophylaxis, including nonpharmacologic and pharmacological strategies and cardiac rehabilitation diminish occurrence of the cardiac dysfunction following SCI.
Abstract: The aim of this article is to analyze cardiac dysfunctions occurring after spinal cord injury (SCI). Cardiac dysfunctions are common complications following SCI. Cardiovascular disturbances are the leading causes of morbidity and mortality in both acute and chronic stages of SCI. We reviewed epidemiology of cardiac disturbances after SCI, and neuroanatomy and pathophysiology of autonomic nervous system, sympathetic and parasympathetic. SCI causes disruption of descendent pathways from central control centers to spinal sympathetic neurons, originating into intermediolateral nuclei of T1-L2 spinal cord segments. Loss of supraspinal control over sympathetic nervous system results in reduced overall sympathetic activity below the level of injury and unopposed parasympathetic outflow through intact vagal nerve. SCI associates significant cardiac dysfunction. Impairment of autonomic nervous control system, mostly in patients with cervical or high thoracic SCI, causes cardiac dysrrhythmias, especially bradycardia and, rarely, cardiac arrest, or tachyarrhytmias and hypotension. Specific complication dependent on the period of time after trauma like spinal shock and autonomic dysreflexia are also reviewed. Spinal shock occurs during the acute phase following SCI and is a transitory suspension of function and reflexes below the level of the injury. Neurogenic shock, part of spinal shock, consists of severe bradycardia and hypotension. Autonomic dysreflexia appears during the chronic phase, after spinal shock resolution, and it is a life-threatening syndrome of massive imbalanced reflex sympathetic discharge occurring in patients with SCI above the splanchnic sympathetic outflow (T5-T6). Besides all this, additional cardiac complications, such as cardiac deconditioning and coronary heart disease may also occur. Proper prophylaxis, including nonpharmacologic and pharmacological strategies and cardiac rehabilitation diminish occurrence of the cardiac dysfunction following SCI. Each type of cardiac disturbance requires specific treatment.

95 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20239
202219
202141
202057
201931
201814