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Institution

Clinical Trial Service Unit

About: Clinical Trial Service Unit is a based out in . It is known for research contribution in the topics: Population & Stroke. The organization has 428 authors who have published 1387 publications receiving 181920 citations.
Topics: Population, Stroke, Prospective cohort study, Cancer, Randomized controlled trial
Papers published on a yearly basis
Papers
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Journal Article•DOI•
In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

[...]

Anthony H. Goldstone1, Susan M. Richards2, H M Lazarus3, Martin S. Tallman4, Georgina Buck2, Adele K. Fielding1, Alan Kenneth Burnett5, R Chopra6, Peter H. Wiernik7, Letizia Foroni1, Elizabeth Paietta7, Mark R. Litzow8, David I. Marks, Jill Durrant2, Andrew McMillan9, Ian M. Franklin10, Selina M. Luger11, Niculae Ciobanu, Jacob M. Rowe12 •
University College London1, Clinical Trial Service Unit2, University Hospitals of Cleveland3, Northwestern University4, Cardiff University5, National Health Service6, New York Medical College7, Mayo Clinic8, University of Nottingham9, University of Glasgow10, University of Pennsylvania11, Technion – Israel Institute of Technology12
16 Nov 2006-Blood
TL;DR: Matched related allogeneic transplantations for ALL in first complete remission provide the most potent antileukemic therapy and considerable survival benefit for standard-risk patients, but the transplantation-related mortality for high-risk older patients was unacceptably high and abrogated the reduction in relapse risk.

698 citations

Journal Article•DOI•
Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort: A Long-Term Follow-Up Study (LEGACY)

[...]

Rajeev K. Pathak1, Melissa E. Middeldorp1, Megan Meredith1, A. Mehta2, Rajiv Mahajan1, Christopher X. Wong3, Darragh Twomey1, Adrian D. Elliott1, Jonathan M. Kalman4, Walter P. Abhayaratna2, Dennis H. Lau1, Prashanthan Sanders1 •
Royal Adelaide Hospital1, Australian National University2, Clinical Trial Service Unit3, Royal Melbourne Hospital4
26 May 2015-Journal of the American College of Cardiology
TL;DR: Long-term sustained weight loss is associated with significant reduction of AF burden and maintenance of sinus rhythm and in multivariate analyses, weight loss and weight fluctuation were independent predictors of outcomes.

682 citations

Journal Article•DOI•
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study

[...]

Peter J. Campbell1, Linda M. Scott1, Georgina Buck2, Keith Wheatley3, Clare L. East4, Joanne T Marsden1, Audrey Duffy1, Elaine M. Boyd4, Anthony J. Bench4, Michael A. Scott4, George S. Vassiliou4, Donald Milligan, Steve Smith5, Wendy N. Erber4, David Bareford6, Bridget S. Wilkins7, John T. Reilly8, Claire N. Harrison9, Anthony R. Green1, Anthony R. Green4 •
University of Cambridge1, Clinical Trial Service Unit2, University of Birmingham3, National Health Service4, Torbay Hospital5, Russells Hall Hospital6, Royal Victoria Infirmary7, University of Sheffield8, St Thomas' Hospital9
03 Dec 2005-The Lancet
TL;DR: The results suggest that JAK2 V617F-positive essential thrombocythaemia and polycythaemia vera form a biological continuum, with the degree of erythrocytosis determined by physiological or genetic modifiers.

655 citations

Journal Article•DOI•
Global Effects of Smoking, of Quitting, and of Taxing Tobacco

[...]

Prabhat Jha1, Richard Peto2•
University of Toronto1, Clinical Trial Service Unit2
01 Jan 2014-The New England Journal of Medicine
TL;DR: The magnitude of the disease burden from cigarette smoking worldwide and strategies to limit smoking are reviewed.
Abstract: Cigarette smoking is a major cause of illness and death This article reviews both the magnitude of the disease burden from cigarette smoking worldwide and strategies to limit smoking

649 citations

Journal Article•DOI•
Tobacco use in 3 billion individuals from 16 countries: an analysis of nationally representative cross-sectional household surveys.

[...]

Gary A. Giovino1, Sara A. Mirza2, Jonathan M. Samet3, Prakash C. Gupta, Martin J. Jarvis4, Neeraj Bhala5, Richard Peto5, Witold Zatonski, Jason Hsia2, Jeremy Morton2, Krishna Palipudi2, Samira Asma2 •
State University of New York System1, Centers for Disease Control and Prevention2, University of Southern California3, University College London4, Clinical Trial Service Unit5
18 Aug 2012-The Lancet
TL;DR: The first wave of GATS showed high rates ofsmoking in men, early initiation of smoking in women, and low quit ratios, reinforcing the view that efforts to prevent initiation and promote cessation of tobacco use are needed to reduce associated morbidity and mortality.

642 citations

Authors

Showing all 428 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Richard Peto183683231434
Cornelia M. van Duijn1831030146009
Rory Collins162489193407
Naveed Sattar1551326116368
Timothy J. Key14680890810
John Danesh135394100132
Andrew J.S. Coats12782094490
Valerie Beral11447153729
Mike Clarke1131037164328
Robert Clarke11151290049
Robert U. Newton10975342527
Richard Gray10980878580
Braxton D. Mitchell10255849599
Naomi E. Allen10136437057
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2021136
2020116
2019122
201894
2017106
201688