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Institution

Cochin University of Science and Technology

EducationKochi, Kerala, India
About: Cochin University of Science and Technology is a education organization based out in Kochi, Kerala, India. It is known for research contribution in the topics: Thin film & Natural rubber. The organization has 5382 authors who have published 7690 publications receiving 103827 citations. The organization is also known as: CUSAT & Cochin University.


Papers
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Journal ArticleDOI
TL;DR: This paper deals with a continuous review inventory system where arriving demands finding the system out of stock, leave the service area and repeat their request after some random time, which introduces a natural alternative to classical approaches based either on lost demand models or on backlogged models.
Abstract: This paper deals with a continuous review (s,S) inventory system where arriving demands finding the system out of stock, leave the service area and repeat their request after some random time. This assumption introduces a natural alternative to classical approaches based either on lost demand models or on backlogged models. The stochastic model formulation is based on a bidimensional Markov process which is numerically solved to investigate the essential operating characteristics of the system. An optimal design problem is also considered.

67 citations

Journal ArticleDOI
TL;DR: Analytical results for the number of busy servers and waiting customers at pre-arrival and arbitrary epochs and a recursive relation for the partial binomial moments and explicit expressions for the marginal binomial Moments both in transient and steady states are obtained.
Abstract: This paper considers an infinite server queue in discrete time in which arrivals are in batches of variable size X and service is provided in batches of fixed size R. We obtain analytical results for the number of busy servers and waiting customers at pre-arrival and arbitrary epochs. For the number of busy servers we obtain a recursive relation for the partial binomial moments and explicit expressions for the marginal binomial moments both in transient and steady states. Special cases are also considered

67 citations

Journal ArticleDOI
TL;DR: In this article, a compact single-feed multiband planar antenna configuration suitable for GPS, DCS, 2.4/5.8 GHz WLAN applications is presented.
Abstract: A compact single-feed multiband planar antenna configuration suitable for GPS, DCS, 2.4/5.8 GHz WLAN applications is presented. The antenna has dimensions 38/spl times/3/spl times/1.6 mm and offers good radiation and reflection characteristics in the above frequency bands. The antenna has a simple geometry and can be easily fed using a 50 /spl Omega/ coaxial probe.

67 citations

Journal ArticleDOI
01 Apr 2011-Traffic
TL;DR: Results showed that the down‐regulation of ezrin activity in macrophages by a dominant‐negative approach caused reduced F‐actin accumulation on maturing phagosomes, and supported the notion that eZrin is necessary for the fusogenic process itself, promoting the transfer of the lysosome content into the phagosomal lumen.
Abstract: Phagosome maturation is defined as the process by which phagosomes fuse sequentially with endosomes and lysosomes to acquire an acidic pH and hydrolases that degrade ingested particles. While the essential role of actin cytoskeleton remodeling during particle internalization is well established, its role during the later stages of phagosome maturation remains largely unknown. We have previously shown that purified mature phagosomes assemble F-actin at their membrane, and that the ezrin-radixin-moesin (ERM) proteins ezrin and moesin participate in this process. Moreover, we provided evidence that actin assembly on purified phagosomes stimulates their fusion with late endocytic compartments in vitro. In this study, we further investigated the role of ezrin in phagosome maturation. We engineered a structurally open form of ezrin and demonstrated that ezrin binds directly to the actin assembly promoting factor N-WASP (Neural Wiskott-Aldrich Syndrome Protein) by its FERM domain. Using a cell-free system, we found that ezrin stimulates F-actin assembly on purified phagosomes by recruiting the N-WASP-Arp2/3 machinery. Accordingly, we showed that the down-regulation of ezrin activity in macrophages by a dominant-negative approach caused reduced F-actin accumulation on maturing phagosomes. Furthermore, using fluorescence and electron microscopy, we found that ezrin is required for the efficient fusion between phagosomes and lysosomes. Live-cell imaging analysis supported the notion that ezrin is necessary for the fusogenic process itself, promoting the transfer of the lysosome content into the phagosomal lumen.

67 citations

Journal ArticleDOI
TL;DR: In this paper, hybrid polymer networks (HPNs) based on unsaturated polyester resin (UPR) and epoxy resins were synthesized by reactive blending, and the physical, mechanical, and thermal properties of the cured blends were compared with those of the control resin.

67 citations


Authors

Showing all 5433 results

NameH-indexPapersCitations
Pulickel M. Ajayan1761223136241
Maxime Dougados134105469979
Sabu Thomas102155451366
Philippe Ravaud10161841409
David P. Salmon9941943935
Jérôme Bertherat8543824794
Luc Mouthon8456426238
Xavier Bertagna7428518738
Alfred Mahr7322922581
Nicolas Roche7262922845
Charles Chapron7137818048
Benoit Terris6123413353
François Goffinet6053214433
Xavier Puéchal6031613240
Pascal Laugier5848210518
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202318
2022106
2021753
2020613
2019503
2018439