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Institution

Cochrane Collaboration

NonprofitOxford, United Kingdom
About: Cochrane Collaboration is a nonprofit organization based out in Oxford, United Kingdom. It is known for research contribution in the topics: Systematic review & Randomized controlled trial. The organization has 1995 authors who have published 3928 publications receiving 382695 citations.


Papers
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Journal ArticleDOI
09 Jan 2013-BMJ
TL;DR: The SPIRIT 2013 Explanation and Elaboration paper provides important information to promote full understanding of the checklist recommendations and strongly recommends that this explanatory paper be used in conjunction with the SPIRit Statement.
Abstract: High quality protocols facilitate proper conduct, reporting, and external review of clinical trials. However, the completeness of trial protocols is often inadequate. To help improve the content and quality of protocols, an international group of stakeholders developed the SPIRIT 2013 Statement (Standard Protocol Items: Recommendations for Interventional Trials). The SPIRIT Statement provides guidance in the form of a checklist of recommended items to include in a clinical trial protocol. This SPIRIT 2013 Explanation and Elaboration paper provides important information to promote full understanding of the checklist recommendations. For each checklist item, we provide a rationale and detailed description; a model example from an actual protocol; and relevant references supporting its importance. We strongly recommend that this explanatory paper be used in conjunction with the SPIRIT Statement. A website of resources is also available (www.spirit-statement.org). The SPIRIT 2013 Explanation and Elaboration paper, together with the Statement, should help with the drafting of trial protocols. Complete documentation of key trial elements can facilitate transparency and protocol review for the benefit of all stakeholders.

3,108 citations

Journal ArticleDOI
TL;DR: The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden, finding that CVDs remain a major cause of health loss for all regions of the world.

2,525 citations

Journal ArticleDOI
TL;DR: In patients with ruptured intracranial aneurysms suitable for both treatments, endovascular coiling is more likely to result in independent survival at 1 year than neurosurgical clipping; the survival benefit continues for at least 7 years.

2,305 citations


Authors

Showing all 2000 results

NameH-indexPapersCitations
Douglas G. Altman2531001680344
John P. A. Ioannidis1851311193612
Jasvinder A. Singh1762382223370
George A. Wells149941114256
Shah Ebrahim14673396807
Holger J. Schünemann141810113169
Paul G. Shekelle132601101639
Peter Tugwell129948125480
Jeremy M. Grimshaw123691115126
Peter Jüni12159399254
John J. McGrath120791124804
Arne Astrup11486668877
Mike Clarke1131037164328
Rachelle Buchbinder11261394973
Ian Roberts11271451933
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
202210
2021289
2020288
2019215
2018213