Institution
Collège de France
Education•Paris, France•
About: Collège de France is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Dopamine. The organization has 6541 authors who have published 11983 publications receiving 648742 citations. The organization is also known as: College de France.
Topics: Population, Dopamine, Dopaminergic, Receptor, Neural crest
Papers published on a yearly basis
Papers
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TL;DR: A model of the mapping between the numerical symbols and the representations of numerosity on the number line is developed, which shows responses increase monotonically with numerosity, but underestimate the actual numerosity.
342 citations
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TL;DR: The FRET method used to measure the stabilization and selectivity of quadruplex ligands towards the human telomeric G-quadruplex is analysed and the stabilization value depends on the nature of the fluorescent tags, the incubation buffer, and the method chosen for T(m) calculation, complicating a direct comparison of the results obtained by different laboratories.
342 citations
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TL;DR: Developments in molecular and supramolecular design and engineering open perspectives towards the realization of molecular photonic, electronic and ionic devices, that would perform highly selective recognition, reaction and transfer operations for signal and information processing at the molecular level.
Abstract: Supramolecular chemistry is the chemistry of the intermolecular bond, covering the structures and functions of the entities formed by association of two or more chemical species Molecular recognition in the supermolecules formed by receptor-substrate binding rests on the principles of molecular complementarity, as found in spherical and tetrahedral recognition, linear recognition by co-receptors, metallo-receptors, amphilic receptors and anion coordination Supramolecular catalysis by receptors bearing reactive groups effects bond cleavage reactions as well as synthetic bond formation via co-catalysis Lipophilic receptor molecules act as selective carriers for various substrates and allow the setting up of coupled transport processes linked to electron and proton gradients or to light Whereas endo-receptors bind substrates in molecular cavities by convergent interactions, exo-receptors rely on interactions between the surfaces of the receptor and the substrate; thus new types of receptors such as the metallonucleates may be designed In combination with polymolecular assemblies, receptors, carriers and catalysts may lead to molecular and supramolecular devices, defined as structurally organized and functionally integrated chemical systems built on supramolecular architectures Their recognition, transfer and transformation features are analyzed specifically from the point of view of molecular devices that would operate via photons, electrons or ions, thus defining the fields of molecular photonics, electronics and ionics Introduction of photosensitive groups yields photoactive receptors for the design of light conversion and charge separation centres Redox active polyolefinic chains represent molecular wires for electron transfer through membranes Tubular mesophases formed by stacking of suitable macrocyclic receptors may lead to ion channels Molecular self-assembling occurs with acyclic ligands that form complexes with a double helical structure Such developments in molecular and supramolecular design and engineering open perspectives towards the realization of molecular photonic, electronic and ionic devices, that would perform highly selective recognition, reaction and transfer operations for signal and information processing at the molecular level
342 citations
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TL;DR: The Monod-Wyman-Changeux model is reexamined on the basis of a variety of regulatory proteins with known X-ray structures, raising new questions concerning the dynamics of the allosteric transitions and more complex supramolecular ensembles.
Abstract: The Monod-Wyman-Changeux (MWC) model was conceived in 1965 to account for the signal transduction and cooperative properties of bacterial regulatory enzymes and hemoglobin. It was soon extended to pharmacological receptors for neurotransmitters and other macromolecular entities involved in intracellular and intercellular communications. Five decades later, the two main hypotheses of the model are reexamined on the basis of a variety of regulatory proteins with known X-ray structures: (a) Regulatory proteins possess an oligomeric structure with symmetry properties, and (b) the allosteric interactions between topographically distinct sites are mediated by a conformational transition established between a few preestablished states with conservation of symmetry and ligand-directed conformational selection. Several well-documented examples are adequately represented by the MWC model, yet a few possible exceptions are noted. New questions are raised concerning the dynamics of the allosteric transitions and more...
340 citations
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TL;DR: In this article, a spectral interpretation of the critical zeros of the Riemann zeta function is given as an absorption spectrum, while eventual noncritical zeros appear as resonances.
Abstract: We give a spectral interpretation of the critical zeros of the Riemann zeta function as an absorption spectrum, while eventual noncritical zeros appear as resonances. We give a geometric interpretation of the explicit formulas of number theory as a trace formula on the noncommutative space of Adele classes. This reduces the Riemann hypothesis to the validity of the trace formula and eliminates the parameter
$ \delta $
of our previous approach.
340 citations
Authors
Showing all 6597 results
Name | H-index | Papers | Citations |
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Pierre Chambon | 211 | 884 | 161565 |
Irving L. Weissman | 201 | 1141 | 172504 |
David R. Williams | 178 | 2034 | 138789 |
Kari Alitalo | 174 | 817 | 114231 |
Pierre Bourdieu | 153 | 592 | 194586 |
Stanislas Dehaene | 149 | 456 | 86539 |
Howard L. Weiner | 144 | 1047 | 91424 |
Alain Fischer | 143 | 770 | 81680 |
Yves Agid | 141 | 669 | 74441 |
Michel Foucault | 140 | 499 | 191296 |
Jean-Pierre Changeux | 138 | 672 | 76462 |
Jean-Marie Tarascon | 136 | 853 | 137673 |
K. Ganga | 132 | 272 | 99004 |
Jacques Delabrouille | 131 | 354 | 94923 |
G. Patanchon | 128 | 241 | 87233 |