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Showing papers by "Concordia University published in 2018"


Journal ArticleDOI
TL;DR: In this paper, the authors present a comprehensive literature review of TiO2 modification techniques that include approaches for overcoming the inherentTiO2 limitations and improving the photocatalytic degradation of VOCs.

667 citations


Journal ArticleDOI
TL;DR: Fog computing is not a substitute for cloud computing but a powerful complement as discussed by the authors, which enables processing at the edge while still offering the possibility to interact with the cloud. But it still faces several challenges, such as the distance between the cloud and the end devices.
Abstract: Cloud computing with its three key facets (i.e., Infrastructure-as-a-Service, Platform-as-a-Service, and Software-as-a-Service) and its inherent advantages (e.g., elasticity and scalability) still faces several challenges. The distance between the cloud and the end devices might be an issue for latency-sensitive applications such as disaster management and content delivery applications. Service level agreements (SLAs) may also impose processing at locations where the cloud provider does not have data centers. Fog computing is a novel paradigm to address such issues. It enables provisioning resources and services outside the cloud, at the edge of the network, closer to end devices, or eventually, at locations stipulated by SLAs. Fog computing is not a substitute for cloud computing but a powerful complement. It enables processing at the edge while still offering the possibility to interact with the cloud. This paper presents a comprehensive survey on fog computing. It critically reviews the state of the art in the light of a concise set of evaluation criteria. We cover both the architectures and the algorithms that make fog systems. Challenges and research directions are also introduced. In addition, the lessons learned are reviewed and the prospects are discussed in terms of the key role fog is likely to play in emerging technologies such as tactile Internet.

598 citations


Journal ArticleDOI
TL;DR: Modifications to reporting standards for scientific publication were accepted by the Publications and Communications Board of APA and supersede the standards included in the 6th edition of the Publication Manual of the American Psychological Association.
Abstract: Following a review of extant reporting standards for scientific publication, and reviewing 10 years of experience since publication of the first set of reporting standards by the American Psychological Association (APA; APA Publications and Communications Board Working Group on Journal Article Reporting Standards, 2008), the APA Working Group on Quantitative Research Reporting Standards recommended some modifications to the original standards. Examples of modifications include division of hypotheses, analyses, and conclusions into 3 groupings (primary, secondary, and exploratory) and some changes to the section on meta-analysis. Several new modules are included that report standards for observational studies, clinical trials, longitudinal studies, replication studies, and N-of-1 studies. In addition, standards for analytic methods with unique characteristics and output (structural equation modeling and Bayesian analysis) are included. These proposals were accepted by the Publications and Communications Board of APA and supersede the standards included in the 6th edition of the Publication Manual of the American Psychological Association (APA, 2010). (PsycINFO Database Record

541 citations


Journal ArticleDOI
23 Aug 2018
TL;DR: In this paper, 29 teams involving 61 analysts used the same data set to address the same research question: whether soccer referees are more likely to give red cards to dark-skin-toned players than to light-skinned-players.
Abstract: Twenty-nine teams involving 61 analysts used the same data set to address the same research question: whether soccer referees are more likely to give red cards to dark-skin-toned players than to light-skin-toned players. Analytic approaches varied widely across the teams, and the estimated effect sizes ranged from 0.89 to 2.93 (Mdn = 1.31) in odds-ratio units. Twenty teams (69%) found a statistically significant positive effect, and 9 teams (31%) did not observe a significant relationship. Overall, the 29 different analyses used 21 unique combinations of covariates. Neither analysts’ prior beliefs about the effect of interest nor their level of expertise readily explained the variation in the outcomes of the analyses. Peer ratings of the quality of the analyses also did not account for the variability. These findings suggest that significant variation in the results of analyses of complex data may be difficult to avoid, even by experts with honest intentions. Crowdsourcing data analysis, a strategy in which numerous research teams are recruited to simultaneously investigate the same research question, makes transparent how defensible, yet subjective, analytic choices influence research results.

396 citations


Journal ArticleDOI
TL;DR: An integrated fuzzy AHP-VIKOR approach-based framework for sustainable global supplier selection that takes sustainability risks from sub-suppliers (i.e., (1 + n) th-tier suppliers) into account is presented in this article.

373 citations


Journal ArticleDOI
TL;DR: In this paper, a meta-analytic analysis of the relationship between the Barnean resource-based view (RBV) and the Penrosean theory is presented, showing that versatile resources are associated with higher levels of growth, whereas VRIN resources are not.

314 citations


Journal ArticleDOI
TL;DR: A novel computationally intelligent-based electrocardiogram (ECG) signal classification methodology using a deep learning (DL) machine that autonomously learns representative and key features of the PAF to be used by a classification module.
Abstract: In this paper, a novel computationally intelligent-based electrocardiogram (ECG) signal classification methodology using a deep learning (DL) machine is developed. The focus is on patient screening and identifying patients with paroxysmal atrial fibrillation (PAF), which represents a life threatening cardiac arrhythmia. The proposed approach operates with a large volume of raw ECG time-series data as inputs to a deep convolutional neural networks (CNN). It autonomously learns representative and key features of the PAF to be used by a classification module. The features are therefore learned directly from the large time domain ECG signals by using a CNN with one fully connected layer. The learned features can effectively replace the traditional ad hoc and time-consuming user’s hand-crafted features. Our experimental results verify and validate the effectiveness and capabilities of the learned features for PAF patient screening. The main advantages of our proposed approach are to simplify the feature extraction process corresponding to different cardiac arrhythmias and to remove the need for using a human expert to define appropriate and critical features working with a large time-series data set. The extensive simulations and case studies conducted indicate that combining the learned features with other classifiers will significantly improve the performance of the patient screening system as compared to an end-to-end CNN classifier. The effectiveness and capabilities of our proposed ECG DL classification machine is demonstrated and quantitative comparisons with several conventional machine learning classifiers are also provided.

312 citations


Proceedings ArticleDOI
27 Feb 2018
TL;DR: In this paper, the authors adopt and incorporate CapsNets for the problem of brain tumor classification to design an improved architecture which maximizes the accuracy of the classification problem at hand.
Abstract: Brain tumor is considered as one of the deadliest and most common form of cancer both in children and in adults. Consequently, determining the correct type of brain tumor in early stages is of significant importance to devise a precise treatment plan and predict patient's response to the adopted treatment. In this regard, there has been a recent surge of interest in designing Convolutional Neural Networks (CNNs) for the problem of brain tumor type classification. However, CNNs typically require large amount of training data and can not properly handle input transformations. Capsule networks (referred to as CapsNets) are brand new machine learning architectures proposed very recently to overcome these shortcomings of CNNs, and posed to revolutionize deep learning solutions. Of particular interest to this work is that Capsule networks are robust to rotation and affine transformation, and require far less training data, which is the case for processing medical image datasets including brain Magnetic Resonance Imaging (MRI) images. In this paper, we focus to achieve the following four objectives: (i) Adopt and incorporate CapsNets for the problem of brain tumor classification to design an improved architecture which maximizes the accuracy of the classification problem at hand; (ii) Investigate the over-fitting problem of CapsNets based on a real set of MRI images; (iii) Explore whether or not CapsNets are capable of providing better fit for the whole brain images or just the segmented tumor, and; (iv) Develop a visualization paradigm for the output of the CapsNet to better explain the learned features. Our results show that the proposed approach can successfully overcome CNNs for the brain tumor classification problem.

304 citations


Journal ArticleDOI
01 May 2018
TL;DR: In this article, the authors call for rigorous strategic environmental and social assessments, raising the bar for environmental protection worldwide, in the Belt and Road Initiative (B2C) and the Asia-Pacific region.
Abstract: The Belt and Road Initiative will greatly influence the future of global trade. However, it may also promote permanent environmental degradation. We call for rigorous strategic environmental and social assessments, raising the bar for environmental protection worldwide.

289 citations


Journal ArticleDOI
TL;DR: MalDozer is proposed, an automatic Android malware detection and family attribution framework that relies on sequences classification using deep learning techniques that can serve as a ubiquitous malware detection system that is not only deployed on servers, but also on mobile and even IoT devices.

280 citations


Journal ArticleDOI
TL;DR: In this paper, the authors investigate the relationship between Corporate Social Responsibility (CSR) and investment efficiency and provide strong and robust evidence that high CSR involvement decreases investment inefficiency and consequently increases investment efficiency.
Abstract: Using a sample of 21,030 US firm-year observations that represents more than 3000 individual firms over the 1998–2012 period, we investigate the relationship between Corporate Social Responsibility (CSR) and investment efficiency. We provide strong and robust evidence that high CSR involvement decreases investment inefficiency and consequently increases investment efficiency. This result is consistent with our expectations that high CSR firms enjoy low information asymmetry and high stakeholder solidarity (stakeholder theory). Moreover, our findings suggest that CSR components that are directly related to firms’ primary stakeholders (e.g. employee relations, product characteristics, environment, and diversity) are more relevant in reducing investment inefficiency compared with those related to secondary stakeholders (e.g. human rights and community involvement). Finally, additional results show that the effect of CSR on investment efficiency is more pronounced during the subprime crisis. Taken together, our results highlight the important role that CSR plays in shaping firms’ investment behaviour and efficiency.

Proceedings ArticleDOI
27 May 2018
TL;DR: The most comprehensive oracle to date that uses triangulation to create a dataset with considerably reduced bias is created, finding that RMiner has a precision of 98% and recall of 87%, which is a significant improvement over the previous state-of-the-art refactoring detection tools.
Abstract: Refactoring detection algorithms have been crucial to a variety of applications: (i) empirical studies about the evolution of code, tests, and faults, (ii) tools for library API migration, (iii) improving the comprehension of changes and code reviews, etc. However, recent research has questioned the accuracy of the state-of-the-art refactoring detection tools, which poses threats to the reliability of their application. Moreover, previous refactoring detection tools are very sensitive to user-provided similarity thresholds, which further reduces their practical accuracy. In addition, their requirement to build the project versions/revisions under analysis makes them inapplicable in many real-world scenarios. To reinvigorate a previously fruitful line of research that has stifled, we designed, implemented, and evaluated RMiner, a technique that overcomes the above limitations. At the heart of RMiner is an AST-based statement matching algorithm that determines refactoring candidates without requiring user-defined thresholds. To empirically evaluate RMiner, we created the most comprehensive oracle to date that uses triangulation to create a dataset with considerably reduced bias, representing 3,188 refactorings from 185 open-source projects. Using this oracle, we found that RMiner has a precision of 98% and recall of 87%, which is a significant improvement over the previous state-of-the-art.

Journal ArticleDOI
TL;DR: Real-time decentralized demand-side management (RDCDSM) will help the microgrid operator to better deal with uncertainties in the system through better planning its day-ahead electricity generation and purchase, thus increasing the quality of power delivery to the customer.
Abstract: The evolution in microgrid technologies as well as the integration of electric vehicles (EVs), energy storage systems (ESSs), and renewable energy sources will all play a significant role in balancing the planned generation of electricity and its real-time use We propose a real-time decentralized demand-side management (RDCDSM) to adjust the real-time residential load to follow a preplanned day-ahead energy generation by the microgrid, based on predicted customers’ aggregate load A deviation from the predicted demand at the time of consumption is assumed to result in additional cost or penalty inflicted on the deviated customers To develop our system, we formulate a game with mixed strategy which in the first phase (ie, prediction phase) allows each customer to process the day ahead raw predicted demand to reduce the anticipated electricity cost by generating a flattened curve for its forecasted future demand Then, in the second stage (ie, allocation phase), customers play another game with mixed strategy to mitigate the deviation between the instantaneous real-time consumption and the day-ahead predicted one To achieve this, customers exploit renewable energy and ESSs and decide optimal strategies for their charging/discharging, taking into account their operational constraints RDCDSM will help the microgrid operator to better deal with uncertainties in the system through better planning its day-ahead electricity generation and purchase, thus increasing the quality of power delivery to the customer We evaluate the performance of our method against a centralized allocation and an existing decentralized EV charge control noncooperative game method both of which rely on a day ahead demand prediction without any refinement We run simulations with various microgrid configurations, by varying the load and generated power, and compare the outcomes

Journal ArticleDOI
TL;DR: The finite-time multivariable terminal sliding mode control and composite-loop design are pursued to enable integration into the FTC, which can ensure the safety of the postfault vehicle in a timely manner.
Abstract: This paper proposes a fault-tolerant control (FTC) scheme for a hypersonic gliding vehicle to counteract actuator faults and model uncertainties. Starting from the kinematic and aerodynamic models of the hypersonic vehicle, the control-oriented model subject to actuator faults is built. The observers are designed to estimate the information of actuator faults and model uncertainties, and to guarantee the estimation errors for converging to zero in fixed settling time. Subsequently, the finite-time multivariable terminal sliding mode control and composite-loop design are pursued to enable integration into the FTC, which can ensure the safety of the postfault vehicle in a timely manner. Simulation studies of a six degree-of-freedom nonlinear model of the hypersonic gliding vehicle are carried out to manifest the effectiveness of the investigated FTC system.

Journal ArticleDOI
TL;DR: A comprehensive overview of macro-encapsulated PCM and its integration into building envelopes is provided and a number of important issues have seldom been addressed such as material selection and PCM melting processes at a component level, and optimal locations at a system level.

Journal ArticleDOI
TL;DR: In this article, phase change materials (PCMs) have been considered as a useful passive method to absorb the excessive heat during day time and release the stored heat during night time.

Posted Content
TL;DR: In this paper, the authors adopt and incorporate CapsNets for the problem of brain tumor classification to design an improved architecture which maximizes the accuracy of the classification problem at hand.
Abstract: Brain tumor is considered as one of the deadliest and most common form of cancer both in children and in adults. Consequently, determining the correct type of brain tumor in early stages is of significant importance to devise a precise treatment plan and predict patient's response to the adopted treatment. In this regard, there has been a recent surge of interest in designing Convolutional Neural Networks (CNNs) for the problem of brain tumor type classification. However, CNNs typically require large amount of training data and can not properly handle input transformations. Capsule networks (referred to as CapsNets) are brand new machine learning architectures proposed very recently to overcome these shortcomings of CNNs, and posed to revolutionize deep learning solutions. Of particular interest to this work is that Capsule networks are robust to rotation and affine transformation, and require far less training data, which is the case for processing medical image datasets including brain Magnetic Resonance Imaging (MRI) images. In this paper, we focus to achieve the following four objectives: (i) Adopt and incorporate CapsNets for the problem of brain tumor classification to design an improved architecture which maximizes the accuracy of the classification problem at hand; (ii) Investigate the over-fitting problem of CapsNets based on a real set of MRI images; (iii) Explore whether or not CapsNets are capable of providing better fit for the whole brain images or just the segmented tumor, and; (iv) Develop a visualization paradigm for the output of the CapsNet to better explain the learned features. Our results show that the proposed approach can successfully overcome CNNs for the brain tumor classification problem.

Journal ArticleDOI
TL;DR: In this article, the authors investigated the role of materialism in participation in sharing-based programs of the sharing economy cross culturally and found that under certain circumstances, both in America and India, materialism will lead to greater participation in the sharing market.

Journal ArticleDOI
TL;DR: This study intends to help researchers to have an overview of the state-of-the-art in PMS and CS methods and more importantly, to provide directions for optimal powertrain and power management controller designs for cost-effective and environmental-friendly vehicles.
Abstract: This paper comprehensively reviews power management strategies (PMS) and component sizing (CS) methods for hybrid vehicles with more than one energy storage system (ESS). The PMS aims to coordinate the power flow among different ESSs while meeting the drive commands and other constraints; whereas, CS is used to optimize the combination of the components to compose a cost-effective powertrain. However, these two aspects are usually coupled such that it is not reasonable to discuss them separately from a system-level design perspective. Therefore, this review briefly discusses the popular PMS, followed by a detailed CS review in different aspects, including the classic and optimization-based with their own subtypes. In addition, several case studies belonging to different optimization structures are also reviewed in detail to demonstrate the features and the main conclusions of each method. As the comparison results show that with the proper CS methods, the hybrid powertrain witness a large fuel saving compared to their conventional counterparts. Furthermore, factors or issues that affect the performance of the PMS and CS methods are discussed. Meanwhile, the future research trends in PMS and CS are elaborated. This study intends to help researchers to have an overview of the state-of-the-art in PMS and CS methods and more importantly, to provide directions for optimal powertrain and power management controller designs for cost-effective and environmental-friendly vehicles.

Journal ArticleDOI
TL;DR: The proposed study is one of the first few to be conducted in the Canadian context for green supply chain barrier analysis for electronic goods sector and the barriers are investigated through causality and prominence relations which can help decision-makers, policy planners and managers of organisations in addressing those critical few for making green supply network practices a success.
Abstract: Green supply chain management (GSCM) involves consideration of environmental impacts of all the processes involved in a typical supply chain to minimise their negative consequences. In this paper, ...

Journal ArticleDOI
TL;DR: In this article, a Ka-band inset-fed microstrip patches linear antenna array is presented for 5G applications in different countries, which employs 16 elements in an H-plane new configuration.
Abstract: A Ka-band inset-fed microstrip patches linear antenna array is presented for the fifth generation (5G) applications in different countries. The bandwidth is enhanced by stacking parasitic patches on top of each inset-fed patch. The array employs 16 elements in an H-plane new configuration. The radiating patches and their feed lines are arranged in an alternating out-of-phase 180° rotating sequence to decrease the mutual coupling and improve the radiation pattern symmetry. A (24.4%) measured bandwidth (24.35–31.13 GHz) is achieved with −15 dB reflection coefficients and 20 dB mutual coupling between the elements. With uniform amplitude distribution, a maximum broadside gain of 19.88 dBi is achieved. Scanning the main beam to 49.5° from the broadside achieved 18.7 dBi gain with −12.1 dB sidelobe level. These characteristics are in good agreement with the simulations, rendering the antenna to be a good candidate for 5G applications.

Journal ArticleDOI
TL;DR: This article proposes to improve the performance of the existing relay-assisted FSO systems by relaxing both of these highly restrictive assumptions through the integration of UAVs as buffer-aided moving relays into the conventional relay- assistance systems.
Abstract: Relay-assisted FSO systems were proposed as a means for remedying the effects of the various atmospheric impairments on the quality of the FSO signal. Conventional relay-assisted FSO systems, however, are designed around two basic assumptions: relays are buffer-free, and relays are stationary. This article proposes to improve the performance of the existing relay-assisted FSO systems by relaxing both of these highly restrictive assumptions through the integration of UAVs as buffer-aided moving relays into the conventional relay-assisted FSO systems. Specifically, two possible simple integration scenarios are proposed and analyzed through simulation. The obtained simulation results demonstrate the great potential associated with the proposed highly promising, innovative, hybrid FSO architecture. Given that high performance gains are observed under small buffer sizes, it becomes conceivable to employ buffer-aided moving relaying UAVs to serve a variety of other purposes. This includes, for instance, having these UAVs oversee the operation of amateur drones for potential misbehavior or wrongdoing within the area of their deployment.

Journal ArticleDOI
TL;DR: Results of the challenge highlighted that automatic algorithms, including the recent machine learning methods, are still trailing human expertise on both detection and delineation criteria, and it is demonstrated that computing a statistically robust consensus of the algorithms performs closer tohuman expertise on one score (segmentation) although still trailing on detection scores.
Abstract: We present a study of multiple sclerosis segmentation algorithms conducted at the international MICCAI 2016 challenge. This challenge was operated using a new open-science computing infrastructure. This allowed for the automatic and independent evaluation of a large range of algorithms in a fair and completely automatic manner. This computing infrastructure was used to evaluate thirteen methods of MS lesions segmentation, exploring a broad range of state-of-theart algorithms, against a high-quality database of 53 MS cases coming from four centers following a common definition of the acquisition protocol. Each case was annotated manually by an unprecedented number of seven different experts. Results of the challenge highlighted that automatic algorithms, including the recent machine learning methods (random forests, deep learning, …), are still trailing human expertise on both detection and delineation criteria. In addition, we demonstrate that computing a statistically robust consensus of the algorithms performs closer to human expertise on one score (segmentation) although still trailing on detection scores.

Journal ArticleDOI
TL;DR: It is shown how traditional practices for intrusion detection in IoT are unsuitable due to their inherent features providing poor coverage of the IoT domain, and a proposal for future directions in IoT based IDS is presented and evaluated.
Abstract: The Internet-of-Things (IoT) is rapidly becoming ubiquitous. However the heterogeneous nature of devices and protocols in use, the sensitivity of the data contained within, as well as the legal and privacy issues, make security for the IoT a growing research priority and industry concern. With many security practices being unsuitable due to their resource intensive nature, it is deemed important to include second line defences into IoT networks. These systems will also need to be assessed for their efficacy in a variety of different network types and protocols. To shed light on these issues, this paper is concerned with advancements in intrusion detection practices in IoT. It provides a comprehensive review of current intrusion detection systems (IDSs) for IoT technologies, focusing on architecture types. A proposal for future directions in IoT based IDS are then presented and evaluated. We show how traditional practices are unsuitable due to their inherent features providing poor coverage of the IoT domain. In order to develop a secure, robust and optimized solution for these networks, the current research for intrusion detection in IoT will need to move in a different direction. An example of which is proposed in order to illustrate how malicious nodes might be passively detected.

Journal ArticleDOI
TL;DR: There has been a recent embrace of contextual thinking in the organizational sciences as mentioned in this paper, and the added value of a contextual approach is illustrated by how context can shape personality, how it affects the emergence of work designs, and how it benefits the study of organizational demography.
Abstract: Although scholars in the field of organizational behavior have raised concerns about a lack of contextual appreciation, there has been a recent embrace of contextual thinking in the organizational sciences. In this review, I discuss several recent theories and measures of context. The added value of a contextual approach is illustrated by how context can shape personality, how it affects the emergence of work designs, and how it benefits the study of organizational demography. Future research topics include context cue sensitivity, the way context is shaped, the mediators of context effects, and the breadth and limits of contextual impact. A recurrent theme is that although context enables a demarcation of what is distinctive about situations, it also permits integration across research areas and levels of analysis, identifying what they have in common as settings for organizational behavior.

Journal ArticleDOI
TL;DR: Experimental and computational analyses showed that both secondary metabolism and regulation are key factors that are significant in the delineation of Aspergillus species.
Abstract: Aspergillus section Nigri comprises filamentous fungi relevant to biomedicine, bioenergy, health, and biotechnology. To learn more about what genetically sets these species apart, as well as about potential applications in biotechnology and biomedicine, we sequenced 23 genomes de novo, forming a full genome compendium for the section (26 species), as well as 6 Aspergillus niger isolates. This allowed us to quantify both inter- and intraspecies genomic variation. We further predicted 17,903 carbohydrate-active enzymes and 2,717 secondary metabolite gene clusters, which we condensed into 455 distinct families corresponding to compound classes, 49% of which are only found in single species. We performed metabolomics and genetic engineering to correlate genotypes to phenotypes, as demonstrated for the metabolite aurasperone, and by heterologous transfer of citrate production to Aspergillus nidulans. Experimental and computational analyses showed that both secondary metabolism and regulation are key factors that are significant in the delineation of Aspergillus species.

Journal ArticleDOI
TL;DR: The impact of the recent financial crisis on the relation between a firm’s risk and social performance (SP) using a sample of non-financial U.S. firms covering the period 1991–2012 is examined.
Abstract: This paper examines the impact of the recent financial crisis (2008–2009) on the relation between a firm’s risk and social performance (SP) using a sample of non-financial U.S. firms covering the period 1991–2012. We find that the relation between SP and risk is significantly different in the crisis period (post-crisis period) compared to the pre-crisis period. SP reduces volatility during the financial crisis. The risk reduction potential of SP is mainly due to the strengths component of SP. Since the relation of risk is stronger with SP strengths than SP concerns, this implies an asymmetric relation between these SP components and a firm’s risk. Specifically, strengths act as a risk reduction tool during an adverse economic environment.

Journal ArticleDOI
TL;DR: In this article, a theoretical framework for how venture uncertainty, venture quality, and investor opportunity set interrelate is developed to evaluate the performance of initial coin offer (ICO) campaigns.
Abstract: Initial Coin Offerings (ICOs) are a new and unregulated form of crowdfunding that raises funds through a blockchain by selling venture-related tokens or coins in exchange for legal tender or cryptocurrencies. In this paper, we establish token or coin tradability as the primary ICO success measure, and we develop a theoretical framework for how venture uncertainty, venture quality, and investor opportunity set interrelate. We use the largest available dataset to date, consisting of 1,009 ICOs from 2015 to March 2018. Our data highlights that venture uncertainty (not being on Github and Telegram, shorter whitepapers, higher percentage of tokens distributed) is negatively correlated, while higher venture quality (better connected CEOs and larger team size) is positively correlated, with ICO success. Moreover, providing a hard cap in a pre-ICO can help investors measure success in the pre-sale. This is another positive signal of funding success.

Journal ArticleDOI
TL;DR: This focused review takes a cognitive neuroscience of aging perspective in interpreting cognitive motor dual-task findings, and considers the importance of identifying the neural circuits that are engaged by the cognitive task in relation to those that are engage during motor task performance.
Abstract: A substantial corpus of evidence suggests that the cognitive involvement in postural control and gait increases with aging. A large portion of such studies were based on dual-task experimental designs, which typically use the simultaneous performance of a motor task (e.g., static or dynamic balancing, walking) and a continuous cognitive task (e.g., mental arithmetic, tone detection). This focused review takes a cognitive neuroscience of aging perspective in interpreting cognitive motor dual-task findings. Specifically, we consider the importance of identifying the neural circuits that are engaged by the cognitive task in relation to those that are engaged during motor task performance. Following the principle of neural overlap, dual-task interference should be greatest when the cognitive and motor tasks engage the same neural circuits. Moreover, the literature on brain aging in general, and models of dedifferentiation and compensation, in particular, suggest that in cognitive motor dual-task performance, the cognitive task engages different neural substrates in young as compared to older adults. Also considered is the concept of multisensory aging, and the degree to which the age-related decline of other systems (e.g., vision, hearing) contribute to cognitive load. Finally, we discuss recent work on focused cognitive training, exercise and multimodal training of older adults and their effects on postural and gait outcomes. In keeping with the principle of neural overlap, the available cognitive training research suggests that targeting processes such as dividing attention and inhibition lead to improved balance and gait in older adults. However, more studies are needed that include functional neuroimaging during actual, upright performance of gait and balance tasks, in order to directly test the principle of neural overlap, and to better optimize the design of intervention studies to improve gait and posture.

Journal ArticleDOI
Didac Carmona-Gutierrez1, Maria A. Bauer1, Andreas Zimmermann1, Andrés Aguilera2, Nicanor Austriaco3, Kathryn R. Ayscough4, Rena Balzan5, Shoshana Bar-Nun6, Antonio Barrientos7, Peter Belenky8, Marc Blondel9, Ralf J. Braun10, Michael Breitenbach10, William Wc Burhans11, Sabrina Büttner12, Sabrina Büttner1, Duccio Cavalieri13, Michael Chang14, Katrina Kf Cooper15, Manuela Côrte-Real16, Vítor Costa17, Vítor Costa18, Christophe Cullin19, Ian W. Dawes20, Jörn Dengjel21, Martin Mb Dickman22, Tobias Eisenberg1, Birthe Fahrenkrog23, Nicolas Fasel24, Kai-Uwe Fröhlich1, Ali Gargouri, Sergio Giannattasio25, Paola Goffrini26, Campbell W. Gourlay27, Chris M. Grant28, Michael Mt Greenwood29, Nicoletta Guaragnella25, Thomas Heger, Jürgen J. Heinisch30, Eva Herker31, Johannes M. Herrmann32, Sebastian J. Hofer1, Antonio Jiménez-Ruiz33, Helmut Jungwirth1, Katharina Kainz1, Dimitrios P. Kontoyiannis34, Paula Ludovico16, Paula Ludovico35, Stéphen Manon19, Enzo Martegani36, Cristina Mazzoni37, Lynn La Megeney38, Lynn La Megeney39, Christa Meisinger40, Jens Nielsen41, Jens Nielsen42, Thomas Nyström43, Heinz Hd Osiewacz44, Tiago Tf Outeiro, Hay-Oak Park45, Tobias Pendl1, Dina Petranovic42, Stéphane Picot46, Peter Polčic47, Ted Powers48, Mark Ramsdale49, Mark Rinnerthaler50, Patrick Rockenfeller1, Patrick Rockenfeller27, Christoph Ruckenstuhl1, Raffael Schaffrath51, María Segovia52, Fedor Ff Severin53, Amir Sharon6, Stephan J. Sigrist54, Cornelia Sommer-Ruck1, Maria João Sousa16, Johan Jm Thevelein55, Karin Thevissen55, Vladimir I. Titorenko56, Michel Mb Toledano57, Mick F. Tuite27, F-Nora Vögtle40, Benedikt Westermann10, Joris Winderickx55, Silke Wissing, Stefan Wölfl58, Zhaojie J Zhang59, Richard Y. Zhao60, Bing Zhou61, Lorenzo Galluzzi62, Lorenzo Galluzzi63, Guido Kroemer, Frank Madeo1 
University of Graz1, Spanish National Research Council2, Providence College3, University of Sheffield4, University of Malta5, Tel Aviv University6, University of Miami7, Brown University8, French Institute of Health and Medical Research9, University of Bayreuth10, Roswell Park Cancer Institute11, Stockholm University12, University of Florence13, University Medical Center Groningen14, Rowan University15, University of Minho16, Instituto de Biologia Molecular e Celular17, University of Porto18, University of Bordeaux19, University of New South Wales20, University of Fribourg21, Texas A&M University22, Université libre de Bruxelles23, University of Lausanne24, National Research Council25, University of Parma26, University of Kent27, University of Manchester28, Royal Military College of Canada29, University of Osnabrück30, Heinrich Pette Institute31, Kaiserslautern University of Technology32, University of Alcalá33, University of Texas MD Anderson Cancer Center34, RMIT University35, University of Milano-Bicocca36, Sapienza University of Rome37, University of Ottawa38, Ottawa Hospital Research Institute39, University of Freiburg40, Technical University of Denmark41, Chalmers University of Technology42, University of Gothenburg43, Goethe University Frankfurt44, Ohio State University45, Centre national de la recherche scientifique46, Comenius University in Bratislava47, University of Minnesota48, University of Exeter49, University of Salzburg50, University of Kassel51, University of Málaga52, Moscow State University53, Free University of Berlin54, Katholieke Universiteit Leuven55, Concordia University56, Université Paris-Saclay57, Heidelberg University58, University of Wyoming59, University of Maryland, Baltimore60, Tsinghua University61, Cornell University62, Paris Descartes University63
TL;DR: Unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria are proposed.
Abstract: Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cel-lular demise. However, the investigation of yeast cell death is a relatively young field, and a widely accepted set of concepts and terms is still missing. Here, we propose unified criteria for the defi-nition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria. Specifically, we provide consensus guidelines on the differ-ential definition of terms including apoptosis, regulated necrosis, and autophagic cell death, as we refer to additional cell death rou-tines that are relevant for the biology of (at least some species of) yeast. As this area of investigation advances rapidly, changes and extensions to this set of recommendations will be implemented in the years to come. Nonetheless, we strongly encourage the au-thors, reviewers and editors of scientific articles to adopt these collective standards in order to establish an accurate framework for yeast cell death research and, ultimately, to accelerate the pro-gress of this vibrant field of research.